Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS01273  |
| T6SS type | Type Unknown |
| Strain | Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 |
| Replicon (RefSeq) | chromosome (NZ_CP064352) |
| Location | 850912..879397 |
| Function | anti-bacterial |
| Comment | Kp43816 possess T6SS-dependent anti-bacterial activity |
| References | [1] Storey D, McNally A, |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | TssA | TssE | TssF | TssG | TssI | TssJ | TssK | TssL | VasK |
| Number | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| IT767_RS03955 | 846170..846979 | + | 810 | WP_074456609.1 | substrate-binding domain-containing protein | ||
| IT767_RS03960 | 846954..847853 | - | 900 | WP_004152315.1 | LysR family transcriptional regulator | ||
| IT767_RS03965 | 847963..848445 | - | 483 | WP_002910657.1 | cold shock domain-containing protein | ||
| IT767_RS03970 | 848636..849334 | + | 699 | WP_002910654.1 | RluA family pseudouridine synthase | ||
| IT767_RS03975 | 849360..849899 | - | 540 | WP_002910652.1 | DUF2058 domain-containing protein | ||
| IT767_RS03980 | 850014..850343 | - | 330 | WP_038431315.1 | gamma-glutamylcyclotransferase | ||
| T6CP015825 | TssK | IT767_RS03985 (tssK) | 850912..852252 | + | 1341 | WP_004899025.1 | type VI secretion system baseplate subunit TssK |
| T6CP015826 | TssL | IT767_RS03990 | 852249..852902 | + | 654 | WP_004184632.1 | type VI secretion system protein TssL, short form |
| IT767_RS03995 | 852906..854603 | + | 1698 | WP_038431316.1 | OmpA family protein | ||
| IT767_RS04000 | 854787..854911 | + | 125 | pseudogene | hypothetical protein | ||
| T6CP015827 | TssI | IT767_RS04005 (vgrG) | 855062..857761 | + | 2700 | WP_038431318.1 | type VI secretion system tip protein VgrG |
| IT767_RS04010 | 857758..859635 | + | 1878 | WP_038431320.1 | phospholipase | ||
| IT767_RS04015 | 859635..860909 | + | 1275 | WP_038431322.1 | sel1 repeat family protein | ||
| IT767_RS04020 | 860947..862014 | + | 1068 | WP_038431324.1 | sel1 repeat family protein | ||
| IT767_RS04025 | 862183..864054 | + | 1872 | WP_038431326.1 | phospholipase | ||
| IT767_RS04030 | 864054..865325 | + | 1272 | WP_038431327.1 | sel1 repeat family protein | ||
| IT767_RS04035 | 865363..866643 | + | 1281 | pseudogene | sel1 repeat family protein | ||
| IT767_RS04040 | 866690..867745 | + | 1056 | WP_101975837.1 | sel1 repeat family protein | ||
| IT767_RS04045 | 867960..868937 | + | 978 | WP_038431331.1 | hypothetical protein | ||
| IT767_RS04050 | 869027..869290 | + | 264 | WP_016532068.1 | PAAR domain-containing protein | ||
| IT767_RS04055 | 869410..870555 | + | 1146 | WP_038431335.1 | hypothetical protein | ||
| T6CP015828 | VasK | IT767_RS04060 | 870661..874056 | + | 3396 | WP_038431336.1 | type VI secretion protein VasK |
| T6CP015829 | TssF | IT767_RS04065 (tssF) | 874190..875953 | + | 1764 | WP_032411370.1 | type VI secretion system baseplate subunit TssF |
| T6CP015830 | TssG | IT767_RS04070 (tssG) | 875983..876999 | + | 1017 | WP_074182212.1 | type VI secretion system baseplate subunit TssG |
| T6CP015831 | TssJ | IT767_RS04075 (tssJ) | 876980..877516 | + | 537 | WP_004175532.1 | type VI secretion system lipoprotein TssJ |
| T6CP015832 | TssE | IT767_RS04080 (tssE) | 877519..877962 | + | 444 | WP_004175538.1 | type VI secretion system baseplate subunit TssE |
| T6CP015833 | TssA | IT767_RS04085 | 877982..879397 | + | 1416 | WP_038431343.1 | type VI secretion system ImpA family N-terminal domain-containing protein |
| IT767_RS04090 | 879529..880443 | + | 915 | WP_002910453.1 | sugar ABC transporter substrate-binding protein | ||
| IT767_RS04095 | 880527..880856 | + | 330 | WP_020323957.1 | DUF1869 domain-containing protein | ||
| IT767_RS04100 (ychF) | 880939..882030 | - | 1092 | WP_002910443.1 | redox-regulated ATPase YchF | ||
| IT767_RS04105 (pth) | 882148..882732 | - | 585 | WP_004180389.1 | aminoacyl-tRNA hydrolase | ||
| IT767_RS04110 (ychH) | 883005..883280 | + | 276 | WP_002910437.1 | stress-induced protein YchH |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|
Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
|---|