Detailed information of T6SS

Note: only experimentally validated proteins are displayed in the graph.


Summary

T6SS ID T6SS01273 experimental
T6SS type Type Unknown
Strain Klebsiella pneumoniae subsp. pneumoniae ATCC 43816
Replicon (RefSeq) chromosome (NZ_CP064352)
Location 850912..879397
Function anti-bacterial
Comment Kp43816 possess T6SS-dependent anti-bacterial activity
References
[1] Storey D, McNally A, strand M, Sa-Pessoa Graca Santos J, Rodriguez-Escudero I, Elmore B, Palacios L, Marshall H, Hobley L, Molina M, Cid VJ, Salminen TA, Bengoechea JA. et al (2020) Klebsiella pneumoniae type VI secretion system-mediated microbial competition is PhoPQ controlled and reactive oxygen species dependent.. PLoS Pathog. 16(3):e1007969. [PudMed:32191774]
experimental Experimental investigation has been performed.

T6SS components and genome coordinates

ComponentTssATssETssFTssGTssITssJTssKTssLVasK
Number111111111


Component ID Component Locus tag (Gene) Coordinate Strand Size (bp) NCBI ID Product
IT767_RS03955 846170..846979 + 810 WP_074456609.1 substrate-binding domain-containing protein
IT767_RS03960 846954..847853 - 900 WP_004152315.1 LysR family transcriptional regulator
IT767_RS03965 847963..848445 - 483 WP_002910657.1 cold shock domain-containing protein
IT767_RS03970 848636..849334 + 699 WP_002910654.1 RluA family pseudouridine synthase
IT767_RS03975 849360..849899 - 540 WP_002910652.1 DUF2058 domain-containing protein
IT767_RS03980 850014..850343 - 330 WP_038431315.1 gamma-glutamylcyclotransferase
T6CP015825 TssK IT767_RS03985 (tssK) 850912..852252 + 1341 WP_004899025.1 type VI secretion system baseplate subunit TssK
T6CP015826 TssL IT767_RS03990 852249..852902 + 654 WP_004184632.1 type VI secretion system protein TssL, short form
IT767_RS03995 852906..854603 + 1698 WP_038431316.1 OmpA family protein
IT767_RS04000 854787..854911 + 125 pseudogene hypothetical protein
T6CP015827 TssI IT767_RS04005 (vgrG) 855062..857761 + 2700 WP_038431318.1 type VI secretion system tip protein VgrG
IT767_RS04010 857758..859635 + 1878 WP_038431320.1 phospholipase
IT767_RS04015 859635..860909 + 1275 WP_038431322.1 sel1 repeat family protein
IT767_RS04020 860947..862014 + 1068 WP_038431324.1 sel1 repeat family protein
IT767_RS04025 862183..864054 + 1872 WP_038431326.1 phospholipase
IT767_RS04030 864054..865325 + 1272 WP_038431327.1 sel1 repeat family protein
IT767_RS04035 865363..866643 + 1281 pseudogene sel1 repeat family protein
IT767_RS04040 866690..867745 + 1056 WP_101975837.1 sel1 repeat family protein
IT767_RS04045 867960..868937 + 978 WP_038431331.1 hypothetical protein
IT767_RS04050 869027..869290 + 264 WP_016532068.1 PAAR domain-containing protein
IT767_RS04055 869410..870555 + 1146 WP_038431335.1 hypothetical protein
T6CP015828 VasK IT767_RS04060 870661..874056 + 3396 WP_038431336.1 type VI secretion protein VasK
T6CP015829 TssF IT767_RS04065 (tssF) 874190..875953 + 1764 WP_032411370.1 type VI secretion system baseplate subunit TssF
T6CP015830 TssG IT767_RS04070 (tssG) 875983..876999 + 1017 WP_074182212.1 type VI secretion system baseplate subunit TssG
T6CP015831 TssJ IT767_RS04075 (tssJ) 876980..877516 + 537 WP_004175532.1 type VI secretion system lipoprotein TssJ
T6CP015832 TssE IT767_RS04080 (tssE) 877519..877962 + 444 WP_004175538.1 type VI secretion system baseplate subunit TssE
T6CP015833 TssA IT767_RS04085 877982..879397 + 1416 WP_038431343.1 type VI secretion system ImpA family N-terminal domain-containing protein
IT767_RS04090 879529..880443 + 915 WP_002910453.1 sugar ABC transporter substrate-binding protein
IT767_RS04095 880527..880856 + 330 WP_020323957.1 DUF1869 domain-containing protein
IT767_RS04100 (ychF) 880939..882030 - 1092 WP_002910443.1 redox-regulated ATPase YchF
IT767_RS04105 (pth) 882148..882732 - 585 WP_004180389.1 aminoacyl-tRNA hydrolase
IT767_RS04110 (ychH) 883005..883280 + 276 WP_002910437.1 stress-induced protein YchH
flank Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files

    

Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
Regulator ID Locus tag (Gene) Regulator type Regulatory pathway Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID Target (Regulation)

experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
Effector ID Locus tag (Gene) Classification Cognate immunity protein Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID

experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed.
Immunity protein ID Locus tag (Gene) Cognate effector Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID

experimental Experimental investigation has been performed.
Accessory protein ID Locus tag (Gene) Type             Organism                 Replicon (Accession) Coordinates (Strand) NCBI ID Related structure protein Related effector