Detailed information of component protein
Summary
| Component ID | T6CP015826 |
| Component protein type | TssL |
| T6SS ID (Type) | T6SS01273  (Type Unknown) |
| Strain | Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 |
| Replicon | chromosome |
| Sequence | Protein sequence (218 a.a.); Nucleotide sequence (654 bp) |
| Reference |
Experimental investigation has been performed on this T6SSExternal database links
| Locus tag (Gene) | IT767_RS03990 |
| Coordinate (Strand) | 852249..852902 (+) |
| NCBI ID | WP_004184632.1 |
| RefSeq | NZ_CP064352 |
| Uniprot ID | A0A7T8TH93_KLEPN |
| KEGG ID | - |
| PDB ID | - |
Pfam domain hit(s)
| Domain | Pfam ID | E-value | Aligned region |
|---|---|---|---|
| DotU | PF09850.11 | 6.4e-37 | 12..203 |
Transmembrane helices
- Transmembrane helices are predicted using TMHMM 2.0 software.
| Prediction | Region | Sequence |
|---|---|---|
| Inside | 1-183 | MNTSESDLINKTFYPGWLMVSQLRCGQPVTDGEALYRQACRWVTEAREALTAGGVSEASAEQMLYAYCALLDESVLNRASQDDGYRRWRKDPLQARFFSTLNAGEELWERIRQLLREPTADAAVLTCFFRTLQLGFVGQYRAEDDERREDVAQALGARVPPFSLTQEAPVVVRASRLRSGRRM |
| Transmembrane helix | 184-206 | YWCGWVAGIVALAALWLTFSSVL |
| Outside | 207-217 | SQMVAQIAGQG |
Signal peptides
- Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
- Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
- Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
| Prediction | Probability | Cleavage site | Signal peptide sequence |
|---|---|---|---|
| Other | 0.9588 | - | - |
Protein sequence: 218 a.a.
>T6CP015826 NZ_CP064352:852249-852902 [Klebsiella pneumoniae subsp. pneumoniae ATCC 43816] [TssL]
MNTSESDLINKTFYPGWLMVSQLRCGQPVTDGEALYRQACRWVTEAREALTAGGVSEASAEQMLYAYCALLDESVLNRAS
QDDGYRRWRKDPLQARFFSTLNAGEELWERIRQLLREPTADAAVLTCFFRTLQLGFVGQYRAEDDERREDVAQALGARVP
PFSLTQEAPVVVRASRLRSGRRMYWCGWVAGIVALAALWLTFSSVLSQMVAQIAGQG*
MNTSESDLINKTFYPGWLMVSQLRCGQPVTDGEALYRQACRWVTEAREALTAGGVSEASAEQMLYAYCALLDESVLNRAS
QDDGYRRWRKDPLQARFFSTLNAGEELWERIRQLLREPTADAAVLTCFFRTLQLGFVGQYRAEDDERREDVAQALGARVP
PFSLTQEAPVVVRASRLRSGRRMYWCGWVAGIVALAALWLTFSSVLSQMVAQIAGQG*
Nucleotide sequence: 654 bp
>T6CP015826 NZ_CP064352:852249-852902 [Klebsiella pneumoniae subsp. pneumoniae ATCC 43816] [TssL]
ATGAATACCTCTGAAAGCGATCTGATCAACAAAACTTTTTACCCGGGCTGGCTGATGGTCAGCCAGTTACGCTGCGGCCA
GCCGGTGACAGATGGCGAGGCGCTCTATCGCCAGGCCTGTCGATGGGTGACCGAGGCGCGCGAGGCGCTGACGGCGGGGG
GAGTCAGTGAAGCCAGCGCTGAGCAGATGCTCTATGCCTACTGCGCGCTGCTCGATGAGAGCGTCCTCAACCGCGCCAGT
CAGGATGATGGCTACCGCAGGTGGCGCAAGGATCCGCTGCAGGCGCGCTTTTTCAGCACTCTCAACGCCGGGGAAGAGCT
CTGGGAACGGATCCGCCAGCTGCTGCGAGAGCCCACGGCGGATGCGGCAGTGCTGACCTGCTTCTTTCGTACTTTACAGC
TGGGATTTGTCGGACAGTACCGCGCCGAGGATGACGAACGGCGTGAGGACGTGGCGCAAGCGCTTGGCGCGCGGGTCCCG
CCGTTCAGCCTGACCCAGGAGGCGCCGGTGGTGGTTCGTGCCTCCCGGCTGCGCAGCGGACGGCGGATGTACTGGTGCGG
CTGGGTGGCTGGCATTGTGGCGCTGGCGGCGCTGTGGTTGACCTTCTCCTCCGTGCTGTCACAGATGGTGGCGCAGATAG
CAGGGCAGGGATAA
ATGAATACCTCTGAAAGCGATCTGATCAACAAAACTTTTTACCCGGGCTGGCTGATGGTCAGCCAGTTACGCTGCGGCCA
GCCGGTGACAGATGGCGAGGCGCTCTATCGCCAGGCCTGTCGATGGGTGACCGAGGCGCGCGAGGCGCTGACGGCGGGGG
GAGTCAGTGAAGCCAGCGCTGAGCAGATGCTCTATGCCTACTGCGCGCTGCTCGATGAGAGCGTCCTCAACCGCGCCAGT
CAGGATGATGGCTACCGCAGGTGGCGCAAGGATCCGCTGCAGGCGCGCTTTTTCAGCACTCTCAACGCCGGGGAAGAGCT
CTGGGAACGGATCCGCCAGCTGCTGCGAGAGCCCACGGCGGATGCGGCAGTGCTGACCTGCTTCTTTCGTACTTTACAGC
TGGGATTTGTCGGACAGTACCGCGCCGAGGATGACGAACGGCGTGAGGACGTGGCGCAAGCGCTTGGCGCGCGGGTCCCG
CCGTTCAGCCTGACCCAGGAGGCGCCGGTGGTGGTTCGTGCCTCCCGGCTGCGCAGCGGACGGCGGATGTACTGGTGCGG
CTGGGTGGCTGGCATTGTGGCGCTGGCGGCGCTGTGGTTGACCTTCTCCTCCGTGCTGTCACAGATGGTGGCGCAGATAG
CAGGGCAGGGATAA