Detailed information of component protein


Summary

Component ID T6CP015833
Component protein type TssA
T6SS ID (Type) T6SS01273 experimental (Type Unknown)
Strain Klebsiella pneumoniae subsp. pneumoniae ATCC 43816
Replicon chromosome
Sequence Protein sequence (472 a.a.); Nucleotide sequence (1416 bp)
Reference
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) IT767_RS04085
Coordinate (Strand) 877982..879397 (+)
NCBI ID WP_038431343.1
RefSeq NZ_CP064352
Uniprot ID UPI0004ED8284
KEGG ID -
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
VasL PF12486.10 2.7e-52 303..447
ImpA_N PF06812.14 5.7e-21 8..112
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Inside 1-246 MMTTHHDRHYKAGGDPRTLADFMALRAEMNKLSHPARPDINWPYAEQLARGLLEHHGADLQTVAWYTLARARLGGVAGINEGLTLMESLLVRQGKNLWPQALPARTEIFRTLSKRLRQVIRTLNLTPEDVESLEQAERSLQSFDAVLQRLEIAPDNQLSDLRALLHSTATRFESLDPAPALPTAPPVAVSDAELPGTLVSEEDAAKVEPVPDLKRRPKAEPLAPPSPAKRPAPVAASTPAAAPRWK
Transmembrane helix 247-269 PFIAGMVTMLAVTGIAVGGWLAL
Outside 270-471 RQSDLPPISVTQNAGPIPGLPATTPPGPVDLPQTQRQLGELARLAPDWAVSYGDQLVRQALIRWPDQAQPLEQQWRQQLSAGALPAENLTGWSEGMQQLQRLADQLNALDEQKGKYLTVSELKTAVFAITQSFNRAVPLEEQLRQLAALPVDQPWPAARGSLAELHLQQLIVEYALLKRKQPASPTAALPRTGEPSVSEAVK


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9867 - -


  Protein sequence: 472 a.a.    

>T6CP015833 NZ_CP064352:877982-879397 [Klebsiella pneumoniae subsp. pneumoniae ATCC 43816] [TssA]
MMTTHHDRHYKAGGDPRTLADFMALRAEMNKLSHPARPDINWPYAEQLARGLLEHHGADLQTVAWYTLARARLGGVAGIN
EGLTLMESLLVRQGKNLWPQALPARTEIFRTLSKRLRQVIRTLNLTPEDVESLEQAERSLQSFDAVLQRLEIAPDNQLSD
LRALLHSTATRFESLDPAPALPTAPPVAVSDAELPGTLVSEEDAAKVEPVPDLKRRPKAEPLAPPSPAKRPAPVAASTPA
AAPRWKPFIAGMVTMLAVTGIAVGGWLALRQSDLPPISVTQNAGPIPGLPATTPPGPVDLPQTQRQLGELARLAPDWAVS
YGDQLVRQALIRWPDQAQPLEQQWRQQLSAGALPAENLTGWSEGMQQLQRLADQLNALDEQKGKYLTVSELKTAVFAITQ
SFNRAVPLEEQLRQLAALPVDQPWPAARGSLAELHLQQLIVEYALLKRKQPASPTAALPRTGEPSVSEAVK*

  Nucleotide sequence: 1416 bp    

>T6CP015833 NZ_CP064352:877982-879397 [Klebsiella pneumoniae subsp. pneumoniae ATCC 43816] [TssA]
ATGATGACAACACACCACGACCGTCACTATAAAGCCGGTGGCGACCCGCGCACGCTGGCTGATTTTATGGCCCTGCGTGC
GGAAATGAACAAGCTCAGCCACCCGGCGCGGCCGGATATTAACTGGCCGTATGCCGAGCAGCTTGCCCGCGGGCTGTTGG
AGCATCACGGCGCGGACCTGCAGACTGTCGCCTGGTATACCCTGGCCCGCGCCCGGCTGGGCGGGGTGGCAGGGATCAAT
GAGGGGCTGACGCTGATGGAGTCGCTGCTGGTTCGTCAGGGGAAAAACCTGTGGCCACAGGCGCTCCCGGCCCGGACAGA
GATCTTCCGCACCCTGAGCAAGCGGCTGCGGCAGGTGATCCGTACCCTGAATCTTACCCCAGAGGATGTTGAGTCGCTTG
AGCAGGCTGAACGTTCGCTGCAAAGCTTCGACGCAGTGCTCCAGCGCCTTGAGATCGCTCCTGACAACCAGCTGAGCGAC
CTGCGGGCGCTACTGCACAGCACGGCAACTCGCTTCGAGAGCCTCGACCCTGCGCCAGCGCTTCCCACCGCGCCGCCGGT
GGCGGTGTCTGACGCGGAACTTCCCGGCACTCTGGTCAGCGAAGAGGATGCGGCGAAGGTTGAGCCAGTGCCAGACCTAA
AACGTAGACCAAAGGCTGAGCCGCTGGCTCCGCCTTCACCTGCAAAGCGGCCCGCGCCGGTGGCGGCGTCTACTCCGGCA
GCCGCGCCGCGCTGGAAGCCGTTTATCGCCGGGATGGTTACCATGCTGGCGGTAACGGGTATCGCCGTCGGCGGATGGCT
GGCGCTGCGTCAGTCCGACTTGCCGCCCATTTCGGTCACCCAAAATGCCGGACCGATACCGGGCCTGCCGGCGACAACGC
CCCCGGGGCCGGTTGATCTGCCACAGACGCAGCGCCAGCTTGGCGAGCTTGCCCGCCTGGCGCCGGACTGGGCGGTCAGC
TACGGCGACCAGCTGGTCCGGCAGGCCCTGATCCGCTGGCCGGATCAGGCGCAACCGCTGGAGCAGCAGTGGCGGCAGCA
GCTGAGTGCTGGCGCATTGCCCGCGGAAAACCTTACCGGCTGGTCGGAGGGCATGCAGCAGCTGCAGCGGCTCGCCGACC
AGCTCAATGCCCTCGACGAGCAGAAGGGGAAGTACCTGACGGTGAGCGAACTGAAAACCGCAGTATTTGCCATCACGCAG
TCGTTTAACCGCGCTGTTCCGCTGGAGGAGCAGCTGCGCCAGCTGGCCGCGCTTCCCGTTGATCAACCCTGGCCAGCCGC
TCGGGGAAGCCTCGCGGAGCTGCATCTGCAACAGCTGATAGTGGAGTATGCCCTGCTGAAGCGAAAACAGCCGGCGTCGC
CGACCGCTGCGCTCCCTAGAACCGGCGAGCCCTCGGTGAGTGAGGCGGTGAAATAA