Detailed information of component protein


Summary

Component ID T6CP015828
Component protein type VasK
T6SS ID (Type) T6SS01273 experimental (Type Unknown)
Strain Klebsiella pneumoniae subsp. pneumoniae ATCC 43816
Replicon chromosome
Sequence Protein sequence (1132 a.a.); Nucleotide sequence (3396 bp)
Reference
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) IT767_RS04060
Coordinate (Strand) 870661..874056 (+)
NCBI ID WP_038431336.1
RefSeq NZ_CP064352
Uniprot ID UPI0004ED88B3
KEGG ID -
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
IcmF-related PF06761.14 6.9e-70 411..727
IcmF_C PF06744.14 2.8e-19 983..1089
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-9 MNATDSILR
Transmembrane helix 10-32 LGSRFGVLMLIAGAILWGIYHYG
Inside 33-43 DKIGLNTLQAK
Transmembrane helix 44-66 LYFCLGLGILILLFRYGGRIVQF
Outside 67-1131 ILGRHLKGQGAPLTSGQHLKPASQSHRAVIEMRQTLRRQYGRFGAGKMTILMLTGSVADVERLAPGLSSQYWQENGDTLLLWGGEPQSASDNDWLFALRKRFCPPVNGLVWVTSAFDHLPAANQHVSPALLSMEDIDNIAHDLAERFSLLGWAVPLYVWSLHPQADDQAGRIVQSVGSLFPPDCQSSQMRQLLSALPSRLLETGVQQVTGNPQHHFLLGLADQLTRQPERISVPLSTFLEPHRALPLAGVVFSPSSPQASHSLKHHWRHDKRWDVLLESLRPSGLKARKIGFPWRRAVSASTAALMLLWAASMTVSFIANRHLVAIAQEQVQQASAGKQPLAVRLHALSALQKTLSQLEYRSQHGAPWYLRAGLSQNDDLLAALFPRYGERAQPLLRDAAAHHLEEQLTAFVQLPPDSPLREKMTKTAYGQLKQYLMLTRPEKMDAAWFATTLMQDWPQRSGIADAVWQGGGPSLLAFYAASLASHPQWRLPVDDGLVSQVRTRLIRQMGQRNSESTLYQKMLAQVANQYADMRLADMTADTDASRLFSTDEVVPGMFTRQAWEQAVQPAIEKVVAERRDEMDWVLSDTKQTAAQSTSPEALRARLAERYFADFSGAWLDFLNSLRWQRAATLSDAIDQLTLMADVRQSPLVALMNTLSVQGRTGQTGEAIADSLVKSARQLFNRDNPPAIDQQSGSRGPLDATFGPVLALLDNRDGGTPTSRLSLQTFLTRVTQVRLRLQQVTNATDPQAMTRLLAQTVFQGKAVDLTETRDYGSLVAAGLGQEWSGFGQTLFVRPMEQAWQQVLTPAAESLNAQWRSAVVEDWNSAFGGRYPFKNTSSEVSLPLLAKYLDSETGRIARFLQTRLNGVLHKEGSRWMADSINAQGLTFNPAFLQAMNTLSHLSDVAFANGEAGLHFALRPGTADGVMQTELVIDNQKLVYMNQMPVWRRFSWPADTEAPGASLSWISTRAGTRQYGDFQGAWGWIRLLDKAVVSAYPGTSSSWSLSWKAPDGLLLNYTLRTEAGEGPLALLALRNFTLPETIFSVRASAERVPLTDDIPGEEGY


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9951 - -


  Protein sequence: 1132 a.a.    

>T6CP015828 NZ_CP064352:870661-874056 [Klebsiella pneumoniae subsp. pneumoniae ATCC 43816] [VasK]
MNATDSILRLGSRFGVLMLIAGAILWGIYHYGDKIGLNTLQAKLYFCLGLGILILLFRYGGRIVQFILGRHLKGQGAPLT
SGQHLKPASQSHRAVIEMRQTLRRQYGRFGAGKMTILMLTGSVADVERLAPGLSSQYWQENGDTLLLWGGEPQSASDNDW
LFALRKRFCPPVNGLVWVTSAFDHLPAANQHVSPALLSMEDIDNIAHDLAERFSLLGWAVPLYVWSLHPQADDQAGRIVQ
SVGSLFPPDCQSSQMRQLLSALPSRLLETGVQQVTGNPQHHFLLGLADQLTRQPERISVPLSTFLEPHRALPLAGVVFSP
SSPQASHSLKHHWRHDKRWDVLLESLRPSGLKARKIGFPWRRAVSASTAALMLLWAASMTVSFIANRHLVAIAQEQVQQA
SAGKQPLAVRLHALSALQKTLSQLEYRSQHGAPWYLRAGLSQNDDLLAALFPRYGERAQPLLRDAAAHHLEEQLTAFVQL
PPDSPLREKMTKTAYGQLKQYLMLTRPEKMDAAWFATTLMQDWPQRSGIADAVWQGGGPSLLAFYAASLASHPQWRLPVD
DGLVSQVRTRLIRQMGQRNSESTLYQKMLAQVANQYADMRLADMTADTDASRLFSTDEVVPGMFTRQAWEQAVQPAIEKV
VAERRDEMDWVLSDTKQTAAQSTSPEALRARLAERYFADFSGAWLDFLNSLRWQRAATLSDAIDQLTLMADVRQSPLVAL
MNTLSVQGRTGQTGEAIADSLVKSARQLFNRDNPPAIDQQSGSRGPLDATFGPVLALLDNRDGGTPTSRLSLQTFLTRVT
QVRLRLQQVTNATDPQAMTRLLAQTVFQGKAVDLTETRDYGSLVAAGLGQEWSGFGQTLFVRPMEQAWQQVLTPAAESLN
AQWRSAVVEDWNSAFGGRYPFKNTSSEVSLPLLAKYLDSETGRIARFLQTRLNGVLHKEGSRWMADSINAQGLTFNPAFL
QAMNTLSHLSDVAFANGEAGLHFALRPGTADGVMQTELVIDNQKLVYMNQMPVWRRFSWPADTEAPGASLSWISTRAGTR
QYGDFQGAWGWIRLLDKAVVSAYPGTSSSWSLSWKAPDGLLLNYTLRTEAGEGPLALLALRNFTLPETIFSVRASAERVP
LTDDIPGEEGY*

  Nucleotide sequence: 3396 bp    

>T6CP015828 NZ_CP064352:870661-874056 [Klebsiella pneumoniae subsp. pneumoniae ATCC 43816] [VasK]
ATGAATGCAACGGATAGCATATTGCGCTTAGGTAGCCGTTTTGGGGTGCTGATGCTGATAGCTGGCGCAATATTGTGGGG
GATATATCACTATGGCGACAAGATTGGATTGAATACGCTGCAAGCGAAACTCTATTTCTGCCTGGGCTTAGGGATCCTTA
TTCTGCTTTTTCGTTATGGCGGCCGTATTGTGCAGTTCATACTCGGCCGCCATCTGAAGGGGCAGGGGGCGCCATTGACA
AGTGGTCAGCATCTGAAGCCGGCTTCCCAGAGTCACCGCGCAGTTATTGAGATGAGGCAGACATTGCGTCGCCAGTATGG
TCGCTTTGGGGCTGGCAAAATGACCATTCTGATGCTCACGGGAAGCGTGGCGGATGTCGAACGCCTTGCACCGGGCCTGA
GTAGCCAGTACTGGCAGGAGAATGGAGACACATTATTGCTTTGGGGTGGGGAACCCCAGAGCGCGTCGGATAATGACTGG
CTTTTTGCTTTGCGTAAACGCTTTTGCCCCCCTGTGAATGGGCTGGTGTGGGTCACTTCTGCGTTTGATCATCTGCCCGC
AGCCAATCAGCACGTATCCCCCGCTTTGTTGTCCATGGAGGATATAGATAACATTGCCCATGATCTGGCTGAACGTTTCT
CACTGCTAGGGTGGGCTGTACCACTGTATGTCTGGTCGCTGCATCCCCAGGCGGATGATCAGGCCGGGCGCATCGTGCAA
TCTGTCGGCAGTCTCTTCCCGCCAGACTGTCAGTCGTCGCAGATGCGCCAGTTACTTTCGGCGTTGCCTTCAAGACTGTT
AGAGACTGGAGTACAACAGGTCACGGGTAATCCGCAGCATCATTTTCTTCTGGGCCTGGCGGACCAACTCACGCGGCAGC
CGGAGCGGATTAGTGTTCCCCTGTCGACGTTTCTGGAACCTCATCGTGCGTTACCGTTAGCCGGCGTTGTGTTCAGCCCG
TCATCGCCGCAGGCGTCGCACAGCCTGAAGCATCATTGGCGCCACGATAAACGCTGGGACGTGCTACTGGAATCTCTCAG
GCCATCCGGCTTAAAAGCACGAAAGATCGGCTTTCCCTGGCGAAGAGCTGTCTCTGCCTCCACTGCCGCCCTGATGTTAC
TCTGGGCCGCCTCAATGACAGTCTCTTTTATCGCCAACCGCCACCTGGTGGCGATCGCACAGGAGCAGGTGCAGCAGGCC
TCGGCGGGAAAACAGCCGCTGGCCGTACGCCTGCATGCGCTCTCCGCGTTACAGAAAACGCTTTCTCAACTGGAATACCG
CTCGCAGCACGGAGCGCCGTGGTACCTCCGCGCTGGCCTCAGTCAGAACGATGACCTGCTGGCGGCGCTGTTCCCGCGCT
ACGGAGAGAGGGCGCAGCCGCTGCTGCGCGATGCGGCGGCGCATCATCTGGAAGAGCAGCTCACCGCCTTCGTGCAGCTG
CCGCCGGACAGCCCACTGCGTGAGAAGATGACGAAGACCGCTTACGGACAACTGAAACAATATCTGATGTTGACCCGCCC
GGAAAAAATGGACGCCGCGTGGTTCGCCACTACGCTAATGCAGGACTGGCCGCAGCGCTCAGGCATCGCCGACGCCGTCT
GGCAGGGCGGCGGCCCTTCGCTGCTGGCATTTTATGCCGCCAGTCTGGCGTCGCATCCGCAGTGGCGTCTGCCTGTCGAT
GACGGTCTGGTCAGCCAGGTGCGCACACGGTTAATTCGACAGATGGGCCAGCGCAACAGTGAGTCCACGCTTTACCAGAA
GATGCTCGCGCAGGTGGCGAATCAGTATGCCGATATGCGCCTGGCGGATATGACTGCCGACACCGATGCTTCGCGTCTGT
TCAGCACTGATGAGGTGGTGCCGGGCATGTTTACCCGTCAGGCCTGGGAGCAGGCCGTGCAGCCGGCCATTGAGAAAGTG
GTCGCGGAACGCCGCGATGAAATGGACTGGGTGTTGAGCGATACGAAGCAGACTGCCGCGCAGTCGACGTCGCCGGAAGC
TCTGCGAGCCAGGCTGGCGGAGCGTTATTTCGCTGATTTTAGCGGCGCCTGGCTGGATTTCCTCAACAGTTTGCGCTGGC
AGCGCGCGGCGACCCTCTCTGATGCCATTGACCAGCTGACCCTGATGGCCGATGTGCGCCAGTCGCCGCTGGTGGCGCTG
ATGAACACCCTGAGCGTGCAGGGGCGAACCGGCCAGACCGGGGAAGCTATCGCCGATTCGCTGGTCAAATCGGCCAGGCA
GCTGTTCAACCGTGACAACCCACCCGCCATCGATCAGCAGTCCGGCTCGCGCGGTCCTCTGGATGCCACCTTCGGGCCCG
TACTGGCGCTGCTGGACAATCGCGACGGCGGGACACCCACCAGCCGTCTTAGCCTGCAGACCTTCCTGACCCGCGTCACC
CAGGTGCGTCTGCGCCTGCAGCAGGTCACCAACGCCACCGATCCGCAGGCGATGACCCGGTTGCTTGCGCAGACGGTATT
CCAGGGCAAGGCCGTGGATTTAACCGAAACGCGCGACTACGGCAGCCTGGTGGCGGCGGGGCTGGGCCAGGAGTGGAGTG
GATTTGGGCAAACGCTGTTTGTTCGCCCGATGGAACAGGCCTGGCAGCAGGTGCTGACCCCGGCGGCGGAAAGTCTCAAC
GCCCAGTGGCGCAGCGCGGTGGTGGAGGACTGGAATAGCGCTTTTGGCGGTCGCTACCCCTTTAAAAATACCAGCAGTGA
AGTCTCTCTGCCGCTGCTGGCAAAATACCTCGACAGCGAGACCGGGCGCATCGCCCGCTTTCTGCAGACCCGGCTGAACG
GCGTGCTGCATAAAGAGGGGAGCCGCTGGATGGCGGACAGTATCAATGCTCAGGGGCTGACGTTTAACCCGGCCTTTCTG
CAGGCGATGAATACCCTGAGCCATCTCTCCGACGTCGCGTTCGCCAACGGCGAAGCGGGATTGCATTTTGCGCTACGTCC
CGGCACCGCGGACGGCGTGATGCAGACGGAGCTGGTCATCGACAATCAGAAACTTGTCTATATGAACCAGATGCCGGTCT
GGCGGCGGTTCAGCTGGCCCGCTGACACCGAAGCGCCGGGCGCCAGTCTGAGCTGGATCAGTACCCGGGCGGGCACCCGC
CAGTATGGCGATTTCCAGGGCGCCTGGGGGTGGATCCGTCTGCTGGATAAGGCGGTGGTCAGCGCTTATCCCGGAACGAG
CAGCAGCTGGAGCCTGAGCTGGAAAGCGCCGGATGGTCTGTTGCTGAACTACACGCTGCGTACCGAGGCGGGGGAAGGAC
CGCTGGCGCTGCTGGCGCTGCGAAACTTTACGCTACCGGAGACGATATTCAGCGTGCGCGCGTCTGCTGAACGTGTTCCG
CTGACCGACGATATACCCGGCGAAGAGGGATACTGA