Detailed information of component protein


Summary

Component ID T6CP015827
Component protein type TssI
T6SS ID (Type) T6SS01273 experimental (Type Unknown)
Strain Klebsiella pneumoniae subsp. pneumoniae ATCC 43816
Replicon chromosome
Sequence Protein sequence (900 a.a.); Nucleotide sequence (2700 bp)
Reference
experimental Experimental investigation has been performed on this T6SS
External database links

Locus tag (Gene) IT767_RS04005
Coordinate (Strand) 855062..857761 (+)
NCBI ID WP_038431318.1
RefSeq NZ_CP064352
Uniprot ID UPI0004ED9E4B
KEGG ID -
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
Phage_GPD PF05954.13 1.1e-67 35..355
DUF2345 PF10106.11 4.4e-49 612..759
T6SS_Vgr PF13296.8 1.7e-33 491..592
Phage_base_V PF04717.14 4e-07 404..472
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-899 MDTSSIITGTTLNRYQLDIPSCTASLDVEEFSGAEKLSELYYYTITFTSAEKNIDAAQLLSKPVMLTMGGGALQQLADCKRVHGVVTAFRRISSSEDQSKYQITLEPFLSLLDKQFRSHRFFVNKSVPEVVEQVLQEHHLHDWEYEFNLKQHYPRREQINQYQESDLAFIQRLLAEVGIFYFFTLQEEAQSEVVHFADAQRALMFDKTLPVNSPSGMSDSGTESIWGLNITHNVVEANVTTRDYNPRDAQSVLQSATADMTRGNGEGITYGEVYHYKLRHRERGDKIDPQTETANFYARLDHERFLAHQTLITANSTAAWLAPAQVLTVTDSLPSTLPAPVQDPLLITGTGFTASRREALRVSLLAVPYSETLCWRPPLLPRPKVTGTMTARVTSAKVNDIYAWQDASGLYRVKFDPDRDEKGQGQESMPVRLAKPYGGDVYGFHFPLIQGTEVAIAFHEGDPDRPYIAHALHDSRHVDPVTEKNSTRNVIRTPANNKLRMEDKRGEEHIKLSTEYGGKTQLNLGHNVNAQRELRGEGFELRTDKWGAIRAGKGIFITADKQSTASGKILAMQDTLDRLKQAGDEMDSLSRDAQSAKADPAQVEQQLAFMREQIDQLREAVAVLSAPNGVALASGKHLQLTARRNLMLNAGADADMGVMKRLFIGVGEGLSLFVRKLGMKLIANQGPVAIQAQNDQLQLLARKDLEIVSTDSEIHIVAKKKIIINAGGSYITLDPYRIELGTGGDVDVKAADFSYSGPASMKADHPDYPPLQSTVRQSLKLNVAQSPNASESSWAGMPYTLYADGALLKQGVLDERGQISVDHQVVTRSYRLEMANGVSYQIPVAEAYSRPEQGELANRGFHHHTSQAASDINPPSSHTEHRNTYADLLDDHIEQEESQ


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9866 - -


  Protein sequence: 900 a.a.    

>T6CP015827 NZ_CP064352:855062-857761 [Klebsiella pneumoniae subsp. pneumoniae ATCC 43816] [TssI]
MDTSSIITGTTLNRYQLDIPSCTASLDVEEFSGAEKLSELYYYTITFTSAEKNIDAAQLLSKPVMLTMGGGALQQLADCK
RVHGVVTAFRRISSSEDQSKYQITLEPFLSLLDKQFRSHRFFVNKSVPEVVEQVLQEHHLHDWEYEFNLKQHYPRREQIN
QYQESDLAFIQRLLAEVGIFYFFTLQEEAQSEVVHFADAQRALMFDKTLPVNSPSGMSDSGTESIWGLNITHNVVEANVT
TRDYNPRDAQSVLQSATADMTRGNGEGITYGEVYHYKLRHRERGDKIDPQTETANFYARLDHERFLAHQTLITANSTAAW
LAPAQVLTVTDSLPSTLPAPVQDPLLITGTGFTASRREALRVSLLAVPYSETLCWRPPLLPRPKVTGTMTARVTSAKVND
IYAWQDASGLYRVKFDPDRDEKGQGQESMPVRLAKPYGGDVYGFHFPLIQGTEVAIAFHEGDPDRPYIAHALHDSRHVDP
VTEKNSTRNVIRTPANNKLRMEDKRGEEHIKLSTEYGGKTQLNLGHNVNAQRELRGEGFELRTDKWGAIRAGKGIFITAD
KQSTASGKILAMQDTLDRLKQAGDEMDSLSRDAQSAKADPAQVEQQLAFMREQIDQLREAVAVLSAPNGVALASGKHLQL
TARRNLMLNAGADADMGVMKRLFIGVGEGLSLFVRKLGMKLIANQGPVAIQAQNDQLQLLARKDLEIVSTDSEIHIVAKK
KIIINAGGSYITLDPYRIELGTGGDVDVKAADFSYSGPASMKADHPDYPPLQSTVRQSLKLNVAQSPNASESSWAGMPYT
LYADGALLKQGVLDERGQISVDHQVVTRSYRLEMANGVSYQIPVAEAYSRPEQGELANRGFHHHTSQAASDINPPSSHTE
HRNTYADLLDDHIEQEESQ*

  Nucleotide sequence: 2700 bp    

>T6CP015827 NZ_CP064352:855062-857761 [Klebsiella pneumoniae subsp. pneumoniae ATCC 43816] [TssI]
ATGGATACCTCTTCAATAATTACCGGCACCACCCTTAACCGTTACCAGCTGGATATTCCTTCATGTACCGCATCGCTGGA
TGTGGAAGAATTCAGTGGGGCAGAAAAACTGAGTGAACTTTATTATTACACTATTACGTTTACCAGCGCAGAGAAAAATA
TTGATGCCGCACAGCTCCTGAGCAAACCCGTCATGCTGACGATGGGCGGCGGCGCACTGCAGCAGCTGGCGGACTGCAAA
CGCGTCCATGGCGTGGTGACTGCCTTCCGGCGTATCAGCAGTTCAGAAGATCAGTCGAAATATCAGATAACCCTCGAACC
CTTCCTCTCCTTACTGGATAAACAGTTTCGCAGCCACCGTTTTTTCGTGAATAAATCGGTGCCGGAGGTGGTGGAGCAGG
TATTGCAGGAACATCACCTCCATGACTGGGAGTATGAGTTTAATCTCAAGCAACACTATCCGCGGCGCGAGCAAATTAAT
CAGTATCAGGAGAGCGACCTGGCGTTTATCCAGCGCCTGCTGGCAGAGGTGGGGATATTTTATTTCTTCACCCTGCAGGA
AGAGGCCCAGAGCGAAGTGGTCCACTTCGCCGACGCGCAGCGGGCGCTGATGTTCGATAAAACACTTCCTGTAAACAGCC
CGTCCGGGATGAGCGACAGCGGTACGGAATCGATATGGGGTCTGAACATCACGCACAATGTCGTAGAGGCGAACGTCACT
ACCCGGGATTATAACCCCCGCGATGCGCAGAGCGTTCTCCAGTCGGCAACAGCGGATATGACCCGAGGAAATGGTGAAGG
CATCACTTACGGTGAGGTATACCACTATAAGCTTCGCCACCGGGAGCGTGGCGATAAAATCGACCCGCAGACGGAGACCG
CCAACTTCTATGCCCGCCTCGACCATGAGCGTTTTCTGGCTCACCAGACGCTTATTACCGCGAACAGTACTGCAGCCTGG
CTGGCGCCGGCCCAGGTGCTGACCGTTACCGACAGCCTGCCGTCGACCCTGCCTGCGCCCGTACAGGATCCGCTGTTAAT
CACCGGCACCGGTTTTACCGCCAGCCGCCGGGAGGCGCTGCGGGTGTCCCTGCTGGCGGTGCCCTACAGCGAAACATTGT
GCTGGCGTCCGCCGCTGCTGCCGCGCCCGAAGGTGACTGGCACCATGACGGCGCGGGTGACCAGCGCGAAGGTGAATGAT
ATCTATGCCTGGCAAGATGCGTCCGGCCTGTACCGGGTGAAATTTGACCCTGACAGAGATGAGAAAGGGCAGGGGCAGGA
AAGCATGCCGGTGCGTCTCGCCAAACCCTACGGCGGCGACGTGTACGGCTTTCACTTCCCGCTGATCCAGGGCACGGAGG
TGGCGATTGCTTTCCACGAAGGCGACCCTGACCGGCCGTATATTGCGCATGCGCTGCACGACTCGCGGCATGTCGACCCT
GTGACGGAGAAAAACAGCACCCGCAATGTGATTCGTACTCCGGCCAATAATAAGCTGCGAATGGAGGATAAGCGCGGCGA
GGAGCATATCAAGCTCAGCACCGAGTACGGCGGCAAGACGCAGCTGAACCTGGGGCATAACGTGAATGCGCAAAGGGAGT
TGCGGGGCGAGGGGTTTGAGCTCCGGACGGATAAATGGGGGGCGATACGGGCGGGGAAAGGGATCTTTATCACCGCAGAT
AAACAGTCAACCGCCAGCGGCAAGATACTTGCAATGCAGGATACCCTGGACAGGCTTAAGCAGGCAGGTGATGAGATGGA
CTCGCTATCGCGTGATGCCCAGTCGGCTAAAGCCGACCCAGCCCAGGTTGAACAACAGTTAGCTTTTATGCGTGAGCAAA
TTGATCAGCTACGGGAGGCGGTTGCCGTGCTCAGCGCACCAAATGGTGTGGCTCTCGCCAGTGGCAAGCATCTGCAACTA
ACCGCACGTCGCAATCTGATGCTCAATGCCGGGGCAGATGCCGATATGGGCGTAATGAAACGGCTGTTTATTGGCGTGGG
GGAAGGGCTGAGCCTGTTTGTCCGCAAGCTGGGGATGAAATTAATCGCCAATCAGGGGCCCGTGGCTATTCAGGCGCAAA
ACGATCAGTTGCAGCTCCTGGCGCGCAAGGATCTGGAGATTGTCAGTACTGATAGCGAAATTCACATTGTGGCAAAGAAA
AAAATCATCATTAACGCTGGAGGAAGCTATATCACCCTCGATCCCTATCGGATTGAGCTCGGTACTGGCGGTGATGTCGA
CGTCAAAGCCGCGGATTTTTCCTATAGCGGACCCGCCAGCATGAAGGCCGATCATCCGGATTATCCGCCACTTCAGTCCA
CCGTAAGGCAATCGCTGAAACTGAACGTGGCACAGTCGCCAAATGCGTCGGAAAGCAGCTGGGCCGGGATGCCATATACC
CTGTATGCCGATGGCGCCCTGTTGAAACAAGGGGTGCTGGATGAAAGAGGCCAGATATCAGTCGATCACCAGGTCGTGAC
CAGAAGTTACAGGCTGGAGATGGCTAATGGCGTCAGCTATCAGATACCCGTTGCCGAAGCGTACAGTCGCCCTGAACAGG
GTGAACTCGCTAATCGCGGCTTTCACCACCATACCTCGCAGGCTGCATCTGATATTAACCCTCCCTCCTCACATACGGAG
CATCGTAATACTTACGCGGATTTGCTCGATGACCATATTGAACAGGAAGAAAGTCAATGA