Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS01119  |
| T6SS type | Type i4b |
| Strain | Acinetobacter baumannii strain UPAB1 |
| Replicon (RefSeq) | chromosome (NZ_CP032215) |
| Location | 2933094..2965138 |
| Function | - |
| Comment | T6SS constitutively secrete Hcp. |
| References | [1] Di Venanzio G, Moon KH, Weber BS, Lopez J, Ly PM, Potter RF, Dantas G, Feldman MF. et al (2019) Multidrug-resistant plasmids repress chromosomally encoded T6SS to enable their dissemination.. Proc Natl Acad Sci U S A. 116(4):1378-1383. [PudMed:30626645] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | TssA | TssB | TssC | TssD | TssE | TssF | TssG | TssH | TssI | TssK | TssL | TssM |
| Number | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| D1G37_RS13925 | 2929553..2930575 | + | 1023 | WP_000591251.1 | ABC transporter substrate-binding protein | ||
| D1G37_RS13930 | 2930626..2931507 | - | 882 | WP_001000093.1 | ABC transporter ATP-binding protein | ||
| D1G37_RS13935 | 2931507..2932451 | - | 945 | WP_000542522.1 | ABC transporter permease | ||
| D1G37_RS13940 | 2932547..2932948 | - | 402 | WP_000070712.1 | hypothetical protein | ||
| T6CP014329 | TssI | D1G37_RS13945 | 2933094..2935724 | + | 2631 | WP_002011259.1 | type VI secretion system tip protein VgrG |
| D1G37_RS13950 | 2935721..2936659 | + | 939 | WP_000059482.1 | hypothetical protein | ||
| D1G37_RS13955 | 2936664..2939417 | + | 2754 | WP_004736241.1 | hypothetical protein | ||
| D1G37_RS13960 | 2939419..2940195 | + | 777 | WP_000864764.1 | hypothetical protein | ||
| D1G37_RS13965 | 2940199..2940675 | + | 477 | WP_002009182.1 | hypothetical protein | ||
| D1G37_RS13970 | 2940689..2940982 | + | 294 | WP_002009132.1 | hypothetical protein | ||
| D1G37_RS13975 | 2940994..2941899 | + | 906 | WP_000776716.1 | sel1 repeat family protein | ||
| D1G37_RS13980 | 2942155..2942733 | - | 579 | WP_046882975.1 | SUMF1/EgtB/PvdO family nonheme iron enzyme | ||
| D1G37_RS13985 | 2942737..2943827 | - | 1091 | WP_085940413.1 | IS4-like element ISAba1 family transposase | ||
| D1G37_RS13990 | 2943884..2944280 | - | 397 | pseudogene | hypothetical protein | ||
| D1G37_RS13995 | 2945022..2945711 | + | 690 | WP_000869704.1 | hypothetical protein | ||
| T6CP014330 | TssB | D1G37_RS14000 (tssB) | 2945728..2946231 | + | 504 | WP_001119042.1 | type VI secretion system contractile sheath small subunit |
| T6CP014331 | TssC | D1G37_RS14005 (tssC) | 2946224..2947705 | + | 1482 | WP_001066523.1 | type VI secretion system contractile sheath large subunit |
| T6CP014332 | TssD | D1G37_RS14010 | 2947755..2948258 | + | 504 | WP_000653195.1 | type VI secretion system tube protein Hcp |
| T6CP014333 | TssE | D1G37_RS14015 (tssE) | 2948338..2948814 | + | 477 | WP_001047031.1 | type VI secretion system baseplate subunit TssE |
| T6CP014334 | TssF | D1G37_RS14020 (tssF) | 2948831..2950642 | + | 1812 | WP_000568819.1 | type VI secretion system baseplate subunit TssF |
| T6CP014335 | TssG | D1G37_RS14025 (tssG) | 2950606..2951604 | + | 999 | WP_001190397.1 | type VI secretion system baseplate subunit TssG |
| D1G37_RS14030 | 2951601..2953013 | + | 1413 | WP_000591884.1 | hypothetical protein | ||
| T6CP014336 | TssM | D1G37_RS14035 (tssM) | 2953044..2956868 | + | 3825 | WP_046882918.1 | type VI secretion system membrane subunit TssM |
| D1G37_RS14040 (tagF) | 2956906..2957865 | + | 960 | WP_000557241.1 | type VI secretion system-associated protein TagF | ||
| D1G37_RS14045 | 2957868..2958635 | + | 768 | WP_001072404.1 | OmpA family protein | ||
| D1G37_RS14050 | 2958652..2958915 | + | 264 | WP_000168112.1 | PAAR domain-containing protein | ||
| T6CP014337 | TssH | D1G37_RS14055 (tssH) | 2959134..2961815 | + | 2682 | WP_002009235.1 | type VI secretion system ATPase TssH |
| T6CP014338 | TssA | D1G37_RS14060 (tssA) | 2961839..2962933 | + | 1095 | WP_000020713.1 | type VI secretion system protein TssA |
| T6CP014339 | TssK | D1G37_RS14065 (tssK) | 2962950..2964314 | + | 1365 | WP_000471444.1 | type VI secretion system baseplate subunit TssK |
| T6CP014340 | TssL | D1G37_RS14070 (icmH) | 2964332..2965138 | + | 807 | WP_000083629.1 | type IVB secretion system protein IcmH/DotU |
| D1G37_RS14075 | 2965151..2965753 | + | 603 | WP_000046452.1 | hypothetical protein | ||
| D1G37_RS14080 | 2965761..2966714 | + | 954 | WP_000972583.1 | M15 family metallopeptidase | ||
| D1G37_RS14085 | 2966717..2967568 | - | 852 | WP_000460188.1 | LysR family transcriptional regulator | ||
| D1G37_RS14090 | 2967720..2968388 | + | 669 | WP_001232203.1 | ankyrin repeat domain-containing protein | ||
| D1G37_RS14095 | 2968404..2968886 | + | 483 | WP_000646722.1 | nucleoside deaminase | ||
| D1G37_RS14100 | 2968886..2970064 | + | 1179 | WP_000813788.1 | cyanate transporter |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
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