Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS00443  |
| T6SS type | Type i3 |
| Strain | Methylomonas methanica MC09 |
| Replicon (RefSeq) | chromosome (NC_015572) |
| Location | 915765..926524 |
| Function | effector translocation |
| Comment | - |
| References | [1] Silverman JM et al (2013) Haemolysin Coregulated Protein Is an Exported Receptor and Chaperone of Type VI Secretion Substrates. Mol Cell. 51(5):584-93. [PudMed:23954347] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | TagJ | TssA | TssB | TssC | TssD | TssE | TssF | TssG | TssH |
| Number | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| METME_RS04275 | 911243..912682 | + | 1440 | WP_013817551.1 | F0F1 ATP synthase subunit alpha | ||
| METME_RS04280 | 912679..913491 | + | 813 | WP_013817552.1 | F0F1 ATP synthase subunit gamma | ||
| METME_RS04285 | 913546..914016 | - | 471 | WP_049794737.1 | hypothetical protein | ||
| METME_RS04290 | 914136..914531 | + | 396 | pseudogene | hypothetical protein | ||
| METME_RS04295 | 914912..915655 | + | 744 | WP_013817555.1 | response regulator | ||
| T6CP004615 | TssA | METME_RS04300 (tssA) | 915765..916805 | + | 1041 | WP_013817556.1 | type VI secretion system protein TssA |
| T6CP004616 | TssB | METME_RS04305 (tssB) | 916832..917368 | + | 537 | WP_013817557.1 | type VI secretion system contractile sheath small subunit |
| T6CP004617 | TssC | METME_RS04310 (tssC) | 917372..918862 | + | 1491 | WP_013817558.1 | type VI secretion system contractile sheath large subunit |
| T6CP004618 | TssD | METME_RS04315 | 918983..919465 | + | 483 | WP_013817559.1 | type VI secretion system tube protein Hcp |
| T6CP012805 | TagJ | METME_RS04320 | 919535..920344 | + | 810 | WP_013817560.1 | virulence protein SciE type |
| T6CP004619 | TssE | METME_RS04325 (tssE) | 920347..920850 | + | 504 | WP_013817561.1 | type VI secretion system baseplate subunit TssE |
| T6CP004620 | TssF | METME_RS04330 (tssF) | 920853..922736 | + | 1884 | WP_013817562.1 | type VI secretion system baseplate subunit TssF |
| T6CP004621 | TssG | METME_RS04335 (tssG) | 922700..923764 | + | 1065 | WP_013817563.1 | type VI secretion system baseplate subunit TssG |
| T6CP004622 | TssH | METME_RS04340 (tssH) | 923804..926524 | + | 2721 | WP_013817564.1 | type VI secretion system ATPase TssH |
| METME_RS04345 | 926790..927809 | + | 1020 | WP_013817565.1 | hypothetical protein | ||
| METME_RS04350 | 927880..928224 | + | 345 | WP_041363745.1 | hypothetical protein | ||
| METME_RS04355 | 928491..929525 | + | 1035 | WP_013817567.1 | hypothetical protein | ||
| METME_RS04360 | 929576..929917 | + | 342 | WP_013817568.1 | hypothetical protein | ||
| METME_RS04365 | 930046..930384 | + | 339 | WP_041365014.1 | PQQ-binding-like beta-propeller repeat protein |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|---|
| EFF00544 |
METME_RS17335 | Tse | IMU00108 |
Methylomonas methanica MC09 | chromosome (NC_015572) | 3824035..3824514 (-) | 333985114 |
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|
| IMU00108 |
Metme_3456 (Tsi2_MM) | EFF00544 |
Methylomonas methanica MC09 | chromosome (NC_015572) | 3823796..3824026 (-) | 333985113 |
Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
|---|