Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS00073  |
| T6SS type | Type i3 |
| Strain | Burkholderia pseudomallei K96243 |
| Replicon (RefSeq) | chromosome II (NC_006351) |
| Location | 221397..248704 |
| Function | - |
| Comment | - |
| References | [1] Burtnick MN et al (2011) The cluster 1 type VI secretion system is a major virulence determinant in Burkholderia pseudomallei. Infect Immun. 79(4):1512-25. [PudMed:21300775] |
Bioinformatics investigation has been performed.T6SS components and genome coordinates
| Component | TagJ | TssA | TssB | TssC | TssD | TssE | TssF | TssG | TssH | TssI | TssJ | TssK | TssL | TssM |
| Number | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| BPS_RS19475 | 217017..217988 | + | 972 | WP_004187502.1 | quinone oxidoreductase | ||
| BPS_RS19480 | 218043..218969 | + | 927 | WP_004523563.1 | dioxygenase | ||
| BPS_RS19485 | 219213..220559 | - | 1347 | WP_038726613.1 | LysR family transcriptional regulator | ||
| BPS_RS19490 | 221144..221377 | - | 234 | WP_004533760.1 | hypothetical protein | ||
| T6CP000638 | TssM | BPS_RS19495 (tssM) | 221397..225473 | - | 4077 | WP_004554727.1 | type VI secretion system membrane subunit TssM |
| T6CP000639 | TssL | BPS_RS19500 (tssL) | 225502..226767 | - | 1266 | WP_004529718.1 | type VI secretion system protein TssL, long form |
| T6CP000640 | TssK | BPS_RS19505 (tssK) | 226856..228202 | - | 1347 | WP_004531523.1 | type VI secretion system baseplate subunit TssK |
| T6CP000641 | TssJ | BPS_RS19510 (tssJ) | 228224..228727 | - | 504 | WP_004529720.1 | type VI secretion system lipoprotein TssJ |
| T6CP000642 | TssD | BPS_RS19515 | 228834..229319 | - | 486 | WP_004188308.1 | type VI secretion system tube protein Hcp |
| T6CP000643 | TssC | BPS_RS19520 (tssC) | 229436..230935 | - | 1500 | WP_004188012.1 | type VI secretion system contractile sheath large subunit |
| T6CP000644 | TssB | BPS_RS19525 (tssB) | 230970..231551 | - | 582 | WP_004523554.1 | type VI secretion system contractile sheath small subunit |
| T6CP000645 | TssH | BPS_RS19530 (tssH) | 231587..234526 | - | 2940 | WP_011205357.1 | type VI secretion system ATPase TssH |
| BPS_RS19535 | 235032..235778 | + | 747 | WP_009939172.1 | TagK domain-containing protein | ||
| T6CP012712 | TagJ | BPS_RS19540 | 235775..236740 | + | 966 | WP_011205359.1 | hypothetical protein |
| T6CP000646 | TssE | BPS_RS19545 (tssE) | 236727..237308 | + | 582 | WP_004551229.1 | type VI secretion system baseplate subunit TssE |
| T6CP000647 | TssF | BPS_RS19550 (tssF) | 237339..239228 | + | 1890 | WP_004523549.1 | type VI secretion system baseplate subunit TssF |
| T6CP000648 | TssG | BPS_RS19555 (tssG) | 239228..240313 | + | 1086 | WP_045606160.1 | type VI secretion system baseplate subunit TssG |
| T6CP000649 | TssA | BPS_RS19560 | 240376..241455 | + | 1080 | WP_172966718.1 | type VI secretion system ImpA family N-terminal domain-containing protein |
| T6CP000650 | TssI | BPS_RS19565 (tssI) | 241527..243854 | + | 2328 | WP_004549277.1 | type VI secretion system tip protein VgrG |
| BPS_RS19570 | 243886..246363 | + | 2478 | WP_004551232.1 | DUF2169 domain-containing protein | ||
| BPS_RS19575 | 246360..247442 | + | 1083 | WP_004529730.1 | pentapeptide repeat-containing protein | ||
| BPS_RS19585 | 247624..248283 | + | 660 | WP_004533832.1 | DUF3540 domain-containing protein | ||
| BPS_RS19590 | 248324..248704 | + | 381 | WP_004529733.1 | DUF4150 domain-containing protein | ||
| BPS_RS19595 | 249406..251322 | - | 1917 | WP_004529735.1 | SMP-30/gluconolactonase/LRE family protein | ||
| BPS_RS19600 | 251662..252555 | - | 894 | WP_004523537.1 | LysR family transcriptional regulator | ||
| BPS_RS19605 | 252651..253427 | + | 777 | WP_004187753.1 | NAD(P)H-dependent oxidoreductase |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|
Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
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