Detailed information of component protein


Summary

Component ID T6CP000638
Component protein type TssM
T6SS ID (Type) T6SS00073 insolico (Type i3)
Strain Burkholderia pseudomallei K96243
Replicon chromosome II
Sequence Protein sequence (1359 a.a.); Nucleotide sequence (4077 bp)
Reference
insolico Bioinformatics investigation has been performed on this T6SS
External database links

Locus tag (Gene) BPS_RS19495
Coordinate (Strand) 221397..225473 (-)
NCBI ID WP_004554727.1
RefSeq NC_006351
Uniprot ID -
KEGG ID -
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
IcmF-related_N PF14331.8 1.5e-85 314..582
IcmF-related PF06761.14 1.1e-81 634..951
IcmF_C PF06744.14 1.6e-23 1202..1305
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Inside 1-12 MNKFLSFLVSRS
Transmembrane helix 13-35 FIAFVALLAVALVIWFVGPFVAF
Outside 36-39 GGLT
Transmembrane helix 40-62 PLAGAGMRVLAIALLLAGVLLWL
Inside 63-68 AGRPTS
Transmembrane helix 69-91 IVFVALLCVLIWHASPLLAFGGA
Outside 92-100 TPFAAEAVR
Transmembrane helix 101-120 AIAIALVLAAFALHLAFRLL
Inside 121-576 QKARTDPDFLKSLLEFGGKQPESPAAGRLVAVNAAIAGAIARLKGMRSGARGLRRLLRGKRYLYELPWYVTLGSRACGKTSALLNAGLSFPVAAQMPRAAAGLPDHGGSVDWWLTNDAVLIDTAGHYTRHGTSAHAAPLPPAGPAPHAQPFDAAADARRANGQPAGERHAVAMAAAAPSSAAFVDERQAQWRQTVDQAEWLGFLRTLRKHRPREPINGALLAVDVATLTSADDNARHAEAAALRARLADLRAQLGVRFPVYLIVTKTDQLPGFAEYFSALTTEGRAQTWGFTLPYDKETIADEGVHARCADELRALAARLAAGVNTRLQEEHDTQRRRRLAALPEEFLVLTRPLGELIDRVFADSRYDDTQHHATLRGVYFTSAAQTGGEAAAETRTVARRLAAATGRAPAAAARAAQQETSQSFFLHDLLTKIVIPDARLVQPNLRWEYRSRTLS
Transmembrane helix 577-599 LAAHALALLLFAWVAIGLRVSMG
Outside 600-1358 NNDAYLDALARKTAALASRVDQLYKAPKPEAVPDVLTQARSLSAYPGLDLSAPGSGWRFGLYTPPGIVAESSRTYDALEDTLLLPRIVTRIEAVLSQAIADRDPNAAYDALRVYLMLYDRARFDAAQVEAWVLDDWARTDSAAVFGGRASMIAHVEQLFRGERIVQSPLIRNDALIRQARAFLDGSNATERLYERAKAAMNKEAPDEFTLLRAVGPQAGTVFTRASGAPLARGVPGLFTFDGYRRVFDKRLAEFVRTAREDDAWVMGRAYLGDAQKKTAEIANALAGADDPLTDAIRRQYLIEYAQQWDAFLGDIRTIGGTSLAFDLVVLRSFAAPDSPLERLARAAVHETTLAQPEASADRSFLQKASAQLSQQADKALGVRAQERVERELVDNRFAGLREMVTGRADTQTDARPGAPAGKSGLDAVANLLNDYYTALTVSDDALANNSMPPANDTAAKLKMAAQTMPAPFRSVLTGLAAQGSREVNRGIGQLLSRQLQATVGDVCRLAIEGNYPFAPDSKRDVGIEDFTRVFAQGGVIDDFFAKTLAPFVDTSTRPWRYKTLPGATEPVEGPDLEPFQHAKAIREVFFGAPGQKQMAWKADIRIPELDPTITSLAIDVDGQTALYQHGPVAPFAVSWPGPRGGVHAEITASPRIRPDTSAVSTDGPWALLRLLQKGRVSGTATPGRTRVTLDFDGRKAVLDLASTGSVANPLTSDVLKTFRCPGSMPMFSLADTGAPPGLPPGSPAAPTSRVARDGR


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9962 - -


  Protein sequence: 1359 a.a.    

>T6CP000638 NC_006351:c225473-221397 [Burkholderia pseudomallei K96243] [TssM]
MNKFLSFLVSRSFIAFVALLAVALVIWFVGPFVAFGGLTPLAGAGMRVLAIALLLAGVLLWLAGRPTSIVFVALLCVLIW
HASPLLAFGGATPFAAEAVRAIAIALVLAAFALHLAFRLLQKARTDPDFLKSLLEFGGKQPESPAAGRLVAVNAAIAGAI
ARLKGMRSGARGLRRLLRGKRYLYELPWYVTLGSRACGKTSALLNAGLSFPVAAQMPRAAAGLPDHGGSVDWWLTNDAVL
IDTAGHYTRHGTSAHAAPLPPAGPAPHAQPFDAAADARRANGQPAGERHAVAMAAAAPSSAAFVDERQAQWRQTVDQAEW
LGFLRTLRKHRPREPINGALLAVDVATLTSADDNARHAEAAALRARLADLRAQLGVRFPVYLIVTKTDQLPGFAEYFSAL
TTEGRAQTWGFTLPYDKETIADEGVHARCADELRALAARLAAGVNTRLQEEHDTQRRRRLAALPEEFLVLTRPLGELIDR
VFADSRYDDTQHHATLRGVYFTSAAQTGGEAAAETRTVARRLAAATGRAPAAAARAAQQETSQSFFLHDLLTKIVIPDAR
LVQPNLRWEYRSRTLSLAAHALALLLFAWVAIGLRVSMGNNDAYLDALARKTAALASRVDQLYKAPKPEAVPDVLTQARS
LSAYPGLDLSAPGSGWRFGLYTPPGIVAESSRTYDALEDTLLLPRIVTRIEAVLSQAIADRDPNAAYDALRVYLMLYDRA
RFDAAQVEAWVLDDWARTDSAAVFGGRASMIAHVEQLFRGERIVQSPLIRNDALIRQARAFLDGSNATERLYERAKAAMN
KEAPDEFTLLRAVGPQAGTVFTRASGAPLARGVPGLFTFDGYRRVFDKRLAEFVRTAREDDAWVMGRAYLGDAQKKTAEI
ANALAGADDPLTDAIRRQYLIEYAQQWDAFLGDIRTIGGTSLAFDLVVLRSFAAPDSPLERLARAAVHETTLAQPEASAD
RSFLQKASAQLSQQADKALGVRAQERVERELVDNRFAGLREMVTGRADTQTDARPGAPAGKSGLDAVANLLNDYYTALTV
SDDALANNSMPPANDTAAKLKMAAQTMPAPFRSVLTGLAAQGSREVNRGIGQLLSRQLQATVGDVCRLAIEGNYPFAPDS
KRDVGIEDFTRVFAQGGVIDDFFAKTLAPFVDTSTRPWRYKTLPGATEPVEGPDLEPFQHAKAIREVFFGAPGQKQMAWK
ADIRIPELDPTITSLAIDVDGQTALYQHGPVAPFAVSWPGPRGGVHAEITASPRIRPDTSAVSTDGPWALLRLLQKGRVS
GTATPGRTRVTLDFDGRKAVLDLASTGSVANPLTSDVLKTFRCPGSMPMFSLADTGAPPGLPPGSPAAPTSRVARDGR*

  Nucleotide sequence: 4077 bp    

>T6CP000638 NC_006351:c225473-221397 [Burkholderia pseudomallei K96243] [TssM]
ATGAACAAGTTCCTGTCCTTTCTGGTGTCTCGATCGTTCATCGCGTTCGTCGCGCTGCTCGCCGTCGCGCTCGTCATCTG
GTTCGTCGGCCCGTTCGTCGCGTTCGGCGGGCTCACGCCGCTCGCGGGCGCGGGCATGCGCGTCCTCGCGATCGCGCTGC
TGCTGGCGGGCGTGCTGCTGTGGCTCGCGGGCCGGCCGACGAGCATCGTGTTCGTCGCGCTGCTGTGCGTGCTGATCTGG
CATGCGTCGCCGCTGCTCGCGTTCGGCGGCGCGACGCCGTTCGCGGCGGAGGCGGTCCGGGCGATCGCGATCGCGCTCGT
GCTCGCGGCGTTCGCGCTGCACCTTGCGTTCCGGCTGCTGCAAAAGGCGCGCACCGATCCGGATTTTCTGAAGAGCCTGC
TCGAATTCGGCGGCAAGCAGCCCGAATCGCCCGCGGCCGGCCGCCTGGTGGCGGTCAACGCCGCGATCGCCGGCGCGATC
GCGCGCCTGAAAGGCATGCGCAGCGGCGCGCGCGGCCTGCGCCGCCTGTTGCGCGGCAAGCGCTATCTGTACGAACTGCC
GTGGTACGTCACGCTCGGCTCGCGGGCATGCGGCAAGACGAGCGCGCTCCTGAACGCCGGGCTCTCGTTTCCGGTCGCGG
CGCAAATGCCGCGCGCGGCAGCCGGGCTGCCGGATCACGGCGGCTCGGTCGACTGGTGGTTGACCAACGATGCGGTGCTG
ATCGACACGGCCGGCCATTACACGCGTCACGGCACGTCGGCGCACGCGGCGCCGCTGCCGCCCGCCGGGCCCGCGCCGCA
CGCCCAGCCCTTCGACGCGGCCGCCGACGCGCGCCGCGCGAACGGTCAGCCGGCGGGCGAGCGGCACGCCGTCGCGATGG
CCGCGGCGGCGCCGTCGAGCGCCGCGTTCGTCGACGAGCGGCAGGCGCAATGGCGGCAGACCGTCGACCAGGCCGAATGG
CTGGGCTTTCTGCGGACGCTGCGCAAGCATCGGCCGCGCGAGCCGATCAACGGCGCGCTGCTCGCCGTCGACGTCGCCAC
GCTCACGAGCGCCGACGACAATGCGCGCCATGCCGAGGCAGCCGCGCTGCGCGCGCGGCTCGCCGATCTGCGCGCGCAAC
TGGGCGTGCGCTTTCCCGTCTATCTGATCGTCACGAAGACGGACCAGTTGCCGGGCTTCGCCGAATACTTCAGCGCGCTG
ACCACGGAGGGCCGCGCGCAGACGTGGGGGTTCACGCTGCCGTACGACAAGGAGACCATCGCGGACGAAGGCGTCCACGC
GCGCTGCGCCGACGAGCTGCGCGCGTTGGCCGCGCGGCTCGCCGCGGGCGTGAACACCCGCCTGCAGGAAGAGCACGACA
CGCAGCGGCGCCGCCGGCTCGCCGCGCTGCCGGAGGAATTTCTCGTGCTGACACGCCCGCTCGGCGAGCTGATCGATCGC
GTCTTCGCCGATTCCCGCTACGACGACACGCAGCATCACGCGACGCTGCGCGGCGTGTATTTCACGAGCGCCGCGCAGAC
GGGCGGCGAGGCCGCCGCCGAAACGCGCACCGTCGCGCGACGCCTCGCCGCCGCGACGGGCCGCGCGCCGGCCGCGGCCG
CGCGCGCGGCGCAGCAGGAAACCAGCCAGAGCTTCTTCCTGCACGATCTGCTGACGAAGATCGTCATTCCGGACGCACGC
CTCGTCCAGCCGAACCTTCGCTGGGAGTATCGCTCGCGCACGCTGAGCCTCGCCGCTCACGCGCTCGCGCTGCTGCTGTT
CGCGTGGGTCGCGATCGGCCTGCGCGTCAGCATGGGCAACAACGATGCCTATCTCGACGCGCTCGCGCGCAAGACGGCGG
CGCTCGCCTCCCGGGTCGACCAGTTGTACAAGGCGCCGAAGCCCGAGGCCGTGCCCGACGTGCTGACGCAAGCCCGCTCG
CTGAGCGCGTACCCGGGCCTCGATCTGTCCGCGCCGGGCAGCGGCTGGCGGTTCGGCCTGTACACGCCGCCCGGCATCGT
CGCCGAAAGCAGCCGCACGTACGACGCGCTCGAGGACACCCTGCTGCTGCCGCGGATCGTCACGCGCATCGAGGCGGTGC
TGTCGCAGGCGATCGCCGATCGCGATCCGAATGCCGCGTACGACGCGCTGCGCGTCTATCTGATGCTGTACGACCGGGCC
CGCTTCGATGCCGCGCAGGTCGAGGCGTGGGTGCTCGACGACTGGGCGCGAACCGACAGCGCGGCGGTCTTCGGCGGCCG
CGCGTCGATGATCGCGCACGTCGAGCAACTGTTCCGCGGCGAGCGCATCGTGCAATCCCCGCTGATCCGCAACGATGCGC
TGATCCGCCAGGCGCGCGCGTTCCTGGACGGCAGCAACGCGACCGAGCGGCTCTACGAGCGCGCGAAGGCGGCGATGAAT
AAAGAAGCGCCCGACGAGTTCACGCTGCTGCGGGCCGTCGGCCCGCAGGCCGGCACGGTGTTCACGCGCGCGAGCGGCGC
GCCGCTCGCGCGGGGCGTGCCGGGCCTCTTCACGTTCGACGGATACCGGCGCGTGTTCGACAAGCGGCTCGCCGAATTCG
TGCGGACCGCGCGCGAAGACGATGCATGGGTGATGGGCCGCGCGTATCTCGGCGACGCTCAAAAAAAAACGGCTGAGATC
GCGAATGCGCTCGCGGGGGCCGACGATCCGCTGACCGACGCGATCCGCCGGCAATATCTGATCGAATACGCGCAGCAATG
GGACGCGTTTCTCGGCGACATCCGCACGATCGGCGGCACGAGCCTCGCATTCGATCTCGTGGTGCTGCGCAGCTTCGCGG
CGCCGGATTCGCCGCTCGAGCGGCTCGCGCGCGCGGCGGTTCACGAGACGACGCTCGCGCAGCCCGAAGCGAGCGCCGAT
CGCTCGTTCCTGCAAAAGGCGTCCGCCCAGTTGAGCCAGCAGGCGGACAAGGCGCTCGGCGTGCGCGCGCAGGAGCGCGT
CGAGCGCGAGCTCGTCGACAATCGCTTCGCGGGCCTGCGCGAAATGGTGACGGGCCGCGCGGACACGCAAACGGACGCGC
GCCCGGGCGCGCCGGCCGGCAAGAGCGGGCTCGATGCGGTCGCGAACCTGCTGAACGACTACTACACGGCGCTGACCGTC
TCGGACGACGCGCTCGCGAACAACAGCATGCCGCCCGCGAACGATACCGCGGCGAAACTGAAGATGGCCGCGCAGACGAT
GCCCGCGCCGTTTCGCTCGGTGCTGACCGGGCTCGCCGCGCAGGGCTCGCGCGAAGTGAACCGCGGCATCGGCCAGTTGC
TGTCGCGGCAGTTGCAGGCGACGGTAGGCGACGTTTGCCGCCTCGCGATCGAGGGCAACTATCCGTTCGCGCCCGACAGC
AAGCGCGACGTCGGCATCGAGGACTTCACGCGCGTGTTCGCGCAAGGCGGCGTGATCGACGACTTCTTCGCGAAGACGCT
CGCGCCGTTCGTCGACACGTCGACGCGGCCTTGGCGCTACAAGACGCTGCCCGGCGCGACCGAACCGGTGGAGGGCCCCG
ATCTCGAACCGTTTCAGCACGCGAAGGCGATTCGCGAAGTGTTTTTCGGCGCGCCCGGCCAGAAGCAGATGGCGTGGAAG
GCCGACATCCGGATTCCCGAACTGGACCCGACGATCACGAGCCTCGCGATCGACGTCGACGGACAGACGGCGCTCTATCA
GCACGGCCCCGTCGCGCCGTTCGCGGTGAGCTGGCCGGGGCCGCGCGGCGGCGTGCACGCGGAGATCACCGCGAGCCCGC
GCATCCGGCCGGACACGTCGGCGGTGTCGACGGACGGCCCATGGGCGCTGCTGCGCCTGCTTCAGAAGGGACGCGTGAGC
GGCACGGCGACGCCCGGGCGCACGCGCGTCACGCTCGACTTCGACGGCCGCAAGGCGGTGCTCGACCTCGCGAGCACGGG
CAGCGTCGCGAATCCGCTGACGAGCGACGTGCTGAAGACGTTCAGGTGCCCGGGCTCGATGCCGATGTTCAGTCTCGCGG
ACACCGGCGCGCCGCCGGGCTTGCCGCCCGGGAGCCCGGCGGCGCCGACGTCGCGCGTCGCGCGCGACGGGCGGTGA