Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ACGHT2_RS02440 Genome accession   NZ_AP031455
Coordinates   442299..442943 (+) Length   214 a.a.
NCBI ID   WP_013851527.1    Uniprot ID   F5X535
Organism   Streptococcus pasteurianus strain k46-0107-A9     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 437299..447943
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACGHT2_RS02420 (K460107A9_04130) - 437886..438623 (+) 738 WP_003063530.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  ACGHT2_RS02425 (K460107A9_04140) pknB 438623..440503 (+) 1881 WP_003063531.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  ACGHT2_RS02430 (K460107A9_04150) liaF 440598..441293 (+) 696 WP_003063532.1 cell wall-active antibiotics response protein LiaF -
  ACGHT2_RS02435 (K460107A9_04160) - 441290..442315 (+) 1026 WP_013851526.1 sensor histidine kinase -
  ACGHT2_RS02440 (K460107A9_04170) vraR 442299..442943 (+) 645 WP_013851527.1 response regulator transcription factor Regulator
  ACGHT2_RS02445 (K460107A9_04180) - 443061..444461 (+) 1401 WP_069789204.1 Cof-type HAD-IIB family hydrolase -
  ACGHT2_RS02450 (K460107A9_04190) - 444461..444817 (+) 357 WP_003063541.1 S1 RNA-binding domain-containing protein -
  ACGHT2_RS02455 (K460107A9_04200) cysK 444930..445859 (-) 930 WP_013851529.1 cysteine synthase A -
  ACGHT2_RS02460 (K460107A9_04210) - 445963..446589 (-) 627 WP_013851530.1 YigZ family protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 23953.74 Da        Isoelectric Point: 4.6633

>NTDB_id=97909 ACGHT2_RS02440 WP_013851527.1 442299..442943(+) (vraR) [Streptococcus pasteurianus strain k46-0107-A9]
MTQKIKIILVDDHEMVRLGLKSFLNLQPDVEVVGEAGNGLDGINLALELKPDVVVMDLVMPEMSGVEATLKLLEEWKEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNAIQKVARGELAIETEVDKKIKAHDMQPELHEDLTARERDILRLL
AKGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFKHHLVPQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=97909 ACGHT2_RS02440 WP_013851527.1 442299..442943(+) (vraR) [Streptococcus pasteurianus strain k46-0107-A9]
ATGACCCAGAAAATTAAAATTATCCTAGTTGATGACCATGAAATGGTACGTTTAGGGTTAAAAAGCTTTTTGAATTTGCA
ACCAGATGTTGAGGTGGTCGGCGAAGCTGGAAATGGTTTAGACGGCATTAATTTGGCTTTAGAATTAAAACCAGATGTGG
TTGTTATGGATTTGGTAATGCCAGAAATGAGCGGTGTCGAAGCGACATTGAAGCTTCTGGAAGAATGGAAAGAAGCTAAG
ATTCTTGTCTTAACATCTTACCTTGATAATGAAAAAATTTATCCTGTCATTGAAGCAGGTGCTAAAGGTTATATGTTAAA
AACATCTAGCGCAGCAGAAATTTTAAATGCCATTCAGAAAGTTGCACGTGGTGAGTTAGCTATTGAAACAGAAGTCGATA
AAAAAATCAAAGCTCATGATATGCAACCAGAATTGCATGAAGATTTGACAGCGCGTGAACGTGATATTTTGAGATTACTT
GCTAAAGGGTATGATAACCAAACTATTGCTGATGAGTTATTTATCTCACTAAAGACCGTCAAAACACACGTTTCAAATAT
TCTAGCTAAGTTAGAAGTCGATGACCGTACACAAGCAGTCGTTTACGCCTTTAAACATCATTTAGTACCGCAAGATGACG
AATAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-203)

Response regulator receiver domain (Response_reg)

(7-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F5X535

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

51.942

96.262

0.5
  degU Bacillus subtilis subsp. subtilis str. 168

37.946

100

0.397

Multiple sequence alignment