Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   R8613_RS10230 Genome accession   NZ_AP026919
Coordinates   1946198..1946524 (-) Length   108 a.a.
NCBI ID   WP_219565693.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700012     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1941198..1951524
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8613_RS10185 (PC0012_19650) rnpA 1941223..1941594 (-) 372 WP_000739246.1 ribonuclease P protein component -
  R8613_RS10190 - 1941611..1941742 (-) 132 WP_000768904.1 hypothetical protein -
  R8613_RS10195 (PC0012_19660) - 1941743..1942933 (-) 1191 WP_000167769.1 acetate kinase -
  R8613_RS10200 (PC0012_19670) comYH 1942984..1943937 (-) 954 WP_050072683.1 class I SAM-dependent methyltransferase Machinery gene
  R8613_RS10205 (PC0012_19680) - 1943998..1944585 (-) 588 WP_000679772.1 class I SAM-dependent methyltransferase -
  R8613_RS10210 (PC0012_19690) comGG/cglG 1944688..1945134 (-) 447 WP_001811371.1 competence type IV pilus minor pilin ComGG Machinery gene
  R8613_RS10215 comGF/cglF 1945112..1945573 (-) 462 WP_000250539.1 competence type IV pilus minor pilin ComGF Machinery gene
  R8613_RS10220 (PC0012_19710) comGE/cglE 1945536..1945838 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  R8613_RS10225 (PC0012_19720) comGD/cglD 1945801..1946205 (-) 405 WP_000588030.1 competence type IV pilus minor pilin ComGD Machinery gene
  R8613_RS10230 (PC0012_19730) comGC/cglC 1946198..1946524 (-) 327 WP_219565693.1 competence type IV pilus major pilin ComGC Machinery gene
  R8613_RS10235 (PC0012_19740) comGB/cglB 1946526..1947542 (-) 1017 WP_078132972.1 competence type IV pilus assembly protein ComGB Machinery gene
  R8613_RS10240 (PC0012_19750) comGA/cglA/cilD 1947490..1948431 (-) 942 WP_001864563.1 competence type IV pilus ATPase ComGA Machinery gene
  R8613_RS10245 (PC0012_19760) - 1948507..1948872 (-) 366 WP_000286415.1 DUF1033 family protein -
  R8613_RS10250 (PC0012_19770) - 1949023..1950081 (-) 1059 WP_044812807.1 zinc-dependent alcohol dehydrogenase family protein -
  R8613_RS10255 (PC0012_19780) nagA 1950244..1951395 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12157.30 Da        Isoelectric Point: 10.0055

>NTDB_id=97909 R8613_RS10230 WP_219565693.1 1946198..1946524(-) (comGC/cglC) [Streptococcus pneumoniae strain PZ900700012]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDATLSKLQG
DGRITEEQVKAYNEYYTKNGGANRKVND

Nucleotide


Download         Length: 327 bp        

>NTDB_id=97909 R8613_RS10230 WP_219565693.1 1946198..1946524(-) (comGC/cglC) [Streptococcus pneumoniae strain PZ900700012]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAGATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTAGAAAAGAATGAAGATGCTACTCTGAGCAAGTTACAAGGA
GATGGGCGCATCACGGAAGAACAGGTTAAAGCTTATAATGAATACTATACTAAAAATGGAGGGGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis SK321

94.444

100

0.944
  comGC/cglC Streptococcus pneumoniae Rx1

93.519

100

0.935
  comGC/cglC Streptococcus pneumoniae D39

93.519

100

0.935
  comGC/cglC Streptococcus pneumoniae R6

93.519

100

0.935
  comGC/cglC Streptococcus pneumoniae TIGR4

93.519

100

0.935
  comGC/cglC Streptococcus mitis NCTC 12261

91.837

90.741

0.833
  comYC Streptococcus gordonii str. Challis substr. CH1

67.961

95.37

0.648
  comYC Streptococcus mutans UA140

62.745

94.444

0.593
  comYC Streptococcus mutans UA159

62.745

94.444

0.593
  comYC Streptococcus suis isolate S10

65.909

81.481

0.537
  comGC Lactococcus lactis subsp. cremoris KW2

55.882

94.444

0.528
  comGC Staphylococcus aureus MW2

47.674

79.63

0.38
  comGC Staphylococcus aureus N315

47.674

79.63

0.38

Multiple sequence alignment