Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   R8613_RS10200 Genome accession   NZ_AP026919
Coordinates   1942984..1943937 (-) Length   317 a.a.
NCBI ID   WP_050072683.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700012     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1937984..1948937
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8613_RS10170 (PC0012_19620) - 1938745..1939368 (-) 624 WP_000932657.1 hypothetical protein -
  R8613_RS10175 (PC0012_19630) jag 1939419..1940405 (-) 987 WP_000260009.1 RNA-binding cell elongation regulator Jag/EloR -
  R8613_RS10180 (PC0012_19640) - 1940424..1941248 (-) 825 WP_000727904.1 membrane protein insertase YidC -
  R8613_RS10185 (PC0012_19650) rnpA 1941223..1941594 (-) 372 WP_000739246.1 ribonuclease P protein component -
  R8613_RS10190 - 1941611..1941742 (-) 132 WP_000768904.1 hypothetical protein -
  R8613_RS10195 (PC0012_19660) - 1941743..1942933 (-) 1191 WP_000167769.1 acetate kinase -
  R8613_RS10200 (PC0012_19670) comYH 1942984..1943937 (-) 954 WP_050072683.1 class I SAM-dependent methyltransferase Machinery gene
  R8613_RS10205 (PC0012_19680) - 1943998..1944585 (-) 588 WP_000679772.1 class I SAM-dependent methyltransferase -
  R8613_RS10210 (PC0012_19690) comGG/cglG 1944688..1945134 (-) 447 WP_001811371.1 competence type IV pilus minor pilin ComGG Machinery gene
  R8613_RS10215 comGF/cglF 1945112..1945573 (-) 462 WP_000250539.1 competence type IV pilus minor pilin ComGF Machinery gene
  R8613_RS10220 (PC0012_19710) comGE/cglE 1945536..1945838 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  R8613_RS10225 (PC0012_19720) comGD/cglD 1945801..1946205 (-) 405 WP_000588030.1 competence type IV pilus minor pilin ComGD Machinery gene
  R8613_RS10230 (PC0012_19730) comGC/cglC 1946198..1946524 (-) 327 WP_219565693.1 competence type IV pilus major pilin ComGC Machinery gene
  R8613_RS10235 (PC0012_19740) comGB/cglB 1946526..1947542 (-) 1017 WP_078132972.1 competence type IV pilus assembly protein ComGB Machinery gene
  R8613_RS10240 (PC0012_19750) comGA/cglA/cilD 1947490..1948431 (-) 942 WP_001864563.1 competence type IV pilus ATPase ComGA Machinery gene
  R8613_RS10245 (PC0012_19760) - 1948507..1948872 (-) 366 WP_000286415.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35691.87 Da        Isoelectric Point: 4.2665

>NTDB_id=97904 R8613_RS10200 WP_050072683.1 1942984..1943937(-) (comYH) [Streptococcus pneumoniae strain PZ900700012]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGFKYLKSDGYAIFLAPSDLLTSPQ
SDLLKVWLKEEASLVAMISLPENLFANAKQSKTIFILQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=97904 R8613_RS10200 WP_050072683.1 1942984..1943937(-) (comYH) [Streptococcus pneumoniae strain PZ900700012]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCGGATGCTATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAGTGGATGATTTACTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTCGG
CTATTATCCTGATGATGCCGTTGCGTCGCGTCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGATTTAAGTACCTTAAGTCAGATGGATATGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTGAAAGTCTGGTTGAAAGAGGAGGCAAGTCTGGTTGCTATGATTAGTCTGCCTGAAAATCTCTTTGCTAA
TGCTAAACAATCTAAGACTATTTTTATCCTACAGAAGAAAAGTGAAATAGCAGTGGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.633

98.738

0.539
  comYH Streptococcus mutans UA159

54.313

98.738

0.536

Multiple sequence alignment