Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC/cglC   Type   Machinery gene
Locus tag   U0448_RS04345 Genome accession   NZ_CP139860
Coordinates   845238..845564 (-) Length   108 a.a.
NCBI ID   WP_000738630.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 21011     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 840238..850564
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U0448_RS04300 rnpA 840255..840626 (-) 372 WP_000739246.1 ribonuclease P protein component -
  U0448_RS04305 - 840643..840774 (-) 132 WP_000768904.1 hypothetical protein -
  U0448_RS04310 - 840775..841965 (-) 1191 WP_000167766.1 acetate kinase -
  U0448_RS04315 comYH 842016..842969 (-) 954 WP_000345100.1 class I SAM-dependent methyltransferase Machinery gene
  U0448_RS04320 - 843030..843624 (-) 595 Protein_822 class I SAM-dependent methyltransferase -
  U0448_RS04325 comGG/cglG 843761..844174 (-) 414 WP_000265631.1 competence type IV pilus minor pilin ComGG Machinery gene
  U0448_RS04330 comGF/cglF 844152..844613 (-) 462 WP_000250531.1 competence type IV pilus minor pilin ComGF Machinery gene
  U0448_RS04335 comGE/cglE 844576..844878 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  U0448_RS04340 comGD/cglD 844841..845245 (-) 405 WP_000588024.1 competence type IV pilus minor pilin ComGD Machinery gene
  U0448_RS04345 comGC/cglC 845238..845564 (-) 327 WP_000738630.1 comG operon protein ComGC Machinery gene
  U0448_RS04350 comGB/cglB 845566..846582 (-) 1017 WP_081570974.1 competence type IV pilus assembly protein ComGB Machinery gene
  U0448_RS04355 comGA/cglA/cilD 846530..847471 (-) 942 WP_000249573.1 competence type IV pilus ATPase ComGA Machinery gene
  U0448_RS04360 - 847547..847912 (-) 366 WP_000286415.1 DUF1033 family protein -
  U0448_RS04365 - 848063..849121 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  U0448_RS04370 nagA 849284..850435 (-) 1152 WP_081570975.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence


Protein


Download         Length: 108 a.a.        Molecular weight: 12247.38 Da        Isoelectric Point: 9.8692

>NTDB_id=911336 U0448_RS04345 WP_000738630.1 845238..845564(-) (comGC/cglC) [Streptococcus pneumoniae strain 21011]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKD
DGRITEEQAKAYKEYHDKNGEANRKVND

Nucleotide


Download         Length: 327 bp        

>NTDB_id=911336 U0448_RS04345 WP_000738630.1 845238..845564(-) (comGC/cglC) [Streptococcus pneumoniae strain 21011]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAAATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGAAAAGAATGAAGATGCTAGCCTAAGCAAGTTAAAAGAC
GATGGGCGAATCACGGAAGAACAGGCTAAAGCTTATAAAGAATACCATGATAAAAATGGAGAAGCAAATCGTAAAGTCAA
TGATTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae Rx1

96.296

100

0.963

  comGC/cglC Streptococcus pneumoniae D39

96.296

100

0.963

  comGC/cglC Streptococcus pneumoniae R6

96.296

100

0.963

  comGC/cglC Streptococcus pneumoniae TIGR4

95.37

100

0.954

  comGC/cglC Streptococcus mitis SK321

92.593

100

0.926

  comGC/cglC Streptococcus mitis NCTC 12261

94.898

90.741

0.861

  comYC Streptococcus gordonii str. Challis substr. CH1

67.961

95.37

0.648

  comYC Streptococcus mutans UA159

62.745

94.444

0.593

  comYC Streptococcus mutans UA140

62.745

94.444

0.593

  comGC Lactococcus lactis subsp. cremoris KW2

54.902

94.444

0.519

  comYC Streptococcus suis isolate S10

67.901

75

0.509

  comGC Staphylococcus aureus MW2

46.078

94.444

0.435

  comGC Staphylococcus aureus N315

46.078

94.444

0.435

  comGC Latilactobacillus sakei subsp. sakei 23K

45.349

79.63

0.361