Detailed information NTG0911337

Bioinformatically predicted

Overview

• Name: comGB/cglB
• Type: Machinery gene
• Locus tag: U0448_RS04350
• Genome accession: NZ_CP139860
• Coordinates: 845566..846582 (-)
• Length: 338 a.a.
• NCBI ID: WP_081570974.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 21011
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 840566..851582

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
U0448_RS04305	-	840643..840774 (-)	132	WP_000768904.1	hypothetical protein	-
U0448_RS04310	-	840775..841965 (-)	1191	WP_000167766.1	acetate kinase	-
U0448_RS04315	comYH	842016..842969 (-)	954	WP_000345100.1	class I SAM-dependent methyltransferase	Machinery gene
U0448_RS04320	-	843030..843624 (-)	595	Protein_822	class I SAM-dependent methyltransferase	-
U0448_RS04325	comGG/cglG	843761..844174 (-)	414	WP_000265631.1	competence type IV pilus minor pilin ComGG	Machinery gene
U0448_RS04330	comGF/cglF	844152..844613 (-)	462	WP_000250531.1	competence type IV pilus minor pilin ComGF	Machinery gene
U0448_RS04335	comGE/cglE	844576..844878 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
U0448_RS04340	comGD/cglD	844841..845245 (-)	405	WP_000588024.1	competence type IV pilus minor pilin ComGD	Machinery gene
U0448_RS04345	comGC/cglC	845238..845564 (-)	327	WP_000738630.1	comG operon protein ComGC	Machinery gene
U0448_RS04350	comGB/cglB	845566..846582 (-)	1017	WP_081570974.1	competence type IV pilus assembly protein ComGB	Machinery gene
U0448_RS04355	comGA/cglA/cilD	846530..847471 (-)	942	WP_000249573.1	competence type IV pilus ATPase ComGA	Machinery gene
U0448_RS04360	-	847547..847912 (-)	366	WP_000286415.1	DUF1033 family protein	-
U0448_RS04365	-	848063..849121 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-
U0448_RS04370	nagA	849284..850435 (-)	1152	WP_081570975.1	N-acetylglucosamine-6-phosphate deacetylase	-

Sequence

Protein

• Length: 338 a.a.
• Molecular weight: 38563.68 Da
• Isoelectric Point: 9.6162

>NTDB_id=911337 U0448_RS04350 WP_081570974.1 845566..846582(-) (comGB/cglB) [Streptococcus pneumoniae strain 21011]
MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLDRSALLDKQCVIQMRAGLSQGKSFSEMMESLGCSSAI
VTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLFFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
LGMVGLVSVLALLALTFYKRSSKMNVFSILARLPFIGIFVQTYLTAYYAREWGNMISQGMELTQIFQMMQEQGSQLFKEI
GQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGEVKSKLGSELEIYAEKTWEVFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide

• Length: 1017 bp

>NTDB_id=911337 U0448_RS04350 WP_081570974.1 845566..846582(-) (comGB/cglB) [Streptococcus pneumoniae strain 21011]
ATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAAGCAAAAAAATATCATCACCCTATTTAA
CAATCTCTTTTCTAGCGGTTTTCATCTGGTGGAGACTATCTCCTTTTTAGATAGGAGTGCTTTGTTGGACAAGCAGTGTG
TGATCCAGATGCGTGCGGGCTTGTCTCAAGGGAAATCATTCTCAGAAATGATGGAAAGTTTGGGATGTTCAAGTGCTATT
GTCACTCAGTTATCCCTAGCTGAAGTTCATGGCAATCTCCACCTGAGTTTGGGAAAGATAGAAGAATATCTGGACAATCT
GGCCAAGGTCAAGAAAAAATTGATTGAAGTAGCGACCTATCCCTTGATTTTGCTGTTTTTTCTTCTCTTAATCATGCTGG
GGCTACGGAATTACCTGCTCCCACAACTGGATAGTAGCAATATTGCCACCCGAATTATCGGTAATCTGCCCCAAATTTTT
CTAGGCATGGTAGGGCTTGTTTCCGTGCTTGCCCTTTTAGCACTAACTTTTTATAAAAGAAGTTCTAAGATGAATGTCTT
TTCTATCTTAGCACGCCTTCCCTTTATTGGAATCTTTGTGCAGACCTATTTGACAGCCTATTATGCACGTGAATGGGGGA
ATATGATTTCACAGGGAATGGAGTTGACGCAGATTTTTCAAATGATGCAGGAACAAGGTTCCCAGCTCTTTAAAGAAATC
GGTCAAGATCTGGCTCAAACCCTGAAAAATGGCCGTGAATTTTCTCAGACGATAGGAACCTATCCTTTCTTTAGGAAGGA
ATTGAGTCTCATCATAGAGTATGGGGAAGTTAAGTCCAAGCTGGGTAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGTCTTTTTTACCCGAGTCAACCGCACCATGAATTTGGTGCAGCCACTGGTTTTTATCTTTGTGGCACTGATTATCGTT
TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (24-141)

• Type II secretion system (T2SS), protein F (T2SSF) (209-329)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGB/cglB	Streptococcus pneumoniae Rx1	97.929	100	0.979
comGB/cglB	Streptococcus pneumoniae D39	97.929	100	0.979
comGB/cglB	Streptococcus pneumoniae R6	97.929	100	0.979
comGB/cglB	Streptococcus pneumoniae TIGR4	97.929	100	0.979
comGB/cglB	Streptococcus mitis SK321	94.379	100	0.944
comGB/cglB	Streptococcus mitis NCTC 12261	94.083	100	0.941
comYB	Streptococcus gordonii str. Challis substr. CH1	70.833	99.408	0.704
comYB	Streptococcus mutans UA140	58.176	94.083	0.547
comYB	Streptococcus mutans UA159	58.176	94.083	0.547
comGB	Lactococcus lactis subsp. cremoris KW2	50.898	98.817	0.503