Detailed information NTG0896259

Bioinformatically predicted

Overview

• Name: comGC/cglC
• Type: Machinery gene
• Locus tag: R4705_RS04475
• Genome accession: NZ_CP137115
• Coordinates: 829149..829475 (-)
• Length: 108 a.a.
• NCBI ID: WP_050084189.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 20614-6
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 824149..834475

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4705_RS04430	rnpA	824166..824537 (-)	372	WP_000739246.1	ribonuclease P protein component	-
R4705_RS04435	-	824554..824685 (-)	132	WP_000768904.1	hypothetical protein	-
R4705_RS04440	-	824686..825876 (-)	1191	WP_000167765.1	acetate kinase	-
R4705_RS04445	comYH	825927..826880 (-)	954	WP_050095638.1	class I SAM-dependent methyltransferase	Machinery gene
R4705_RS04450	-	826941..827535 (-)	595	Protein_845	class I SAM-dependent methyltransferase	-
R4705_RS04455	comGG/cglG	827672..828085 (-)	414	WP_050084191.1	competence type IV pilus minor pilin ComGG	Machinery gene
R4705_RS04460	comGF/cglF	828063..828524 (-)	462	WP_050084190.1	competence type IV pilus minor pilin ComGF	Machinery gene
R4705_RS04465	comGE/cglE	828487..828789 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
R4705_RS04470	comGD/cglD	828752..829156 (-)	405	WP_001864568.1	competence type IV pilus minor pilin ComGD	Machinery gene
R4705_RS04475	comGC/cglC	829149..829475 (-)	327	WP_050084189.1	competence type IV pilus major pilin ComGC	Machinery gene
R4705_RS04480	comGB/cglB	829477..830493 (-)	1017	WP_074196785.1	competence type IV pilus assembly protein ComGB	Machinery gene
R4705_RS04485	comGA/cglA/cilD	830441..831382 (-)	942	WP_050084188.1	competence type IV pilus ATPase ComGA	Machinery gene
R4705_RS04490	-	831459..831824 (-)	366	WP_000286415.1	DUF1033 family protein	-
R4705_RS04495	-	831975..833033 (-)	1059	WP_050084187.1	zinc-dependent alcohol dehydrogenase family protein	-
R4705_RS04500	nagA	833196..834347 (-)	1152	WP_001134457.1	N-acetylglucosamine-6-phosphate deacetylase	-

Sequence

Protein

• Length: 108 a.a.
• Molecular weight: 12228.43 Da
• Isoelectric Point: 10.1212

>NTDB_id=896259 R4705_RS04475 WP_050084189.1 829149..829475(-) (comGC/cglC) [Streptococcus pneumoniae strain 20614-6]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLQA
DGRITKEQVKAYNEYYTKNGEANRKVND

Nucleotide

• Length: 327 bp

>NTDB_id=896259 R4705_RS04475 WP_050084189.1 829149..829475(-) (comGC/cglC) [Streptococcus pneumoniae strain 20614-6]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAAATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTAGTGGAAAGTCAGGCAGAGCTTTATAGCTTAGAAAAAAATGAAGATGCTAGCCTAAGTAAGCTACAAGCA
GATGGGCGAATCACAAAAGAACAAGTTAAAGCCTATAATGAATACTATACTAAAAATGGAGAGGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (11-34)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC/cglC	Streptococcus mitis SK321	94.444	100	0.944
comGC/cglC	Streptococcus pneumoniae D39	93.519	100	0.935
comGC/cglC	Streptococcus pneumoniae R6	93.519	100	0.935
comGC/cglC	Streptococcus pneumoniae Rx1	93.519	100	0.935
comGC/cglC	Streptococcus pneumoniae TIGR4	93.519	100	0.935
comGC/cglC	Streptococcus mitis NCTC 12261	92.857	90.741	0.843
comYC	Streptococcus gordonii str. Challis substr. CH1	67.961	95.37	0.648
comYC	Streptococcus mutans UA159	62.745	94.444	0.593
comYC	Streptococcus mutans UA140	62.745	94.444	0.593
comGC	Lactococcus lactis subsp. cremoris KW2	55.882	94.444	0.528
comYC	Streptococcus suis isolate S10	67.901	75	0.509
comGC	Staphylococcus aureus MW2	46.078	94.444	0.435
comGC	Staphylococcus aureus N315	46.078	94.444	0.435
comGC	Latilactobacillus sakei subsp. sakei 23K	45.349	79.63	0.361