Detailed information NTG0895339

Bioinformatically predicted

Overview

• Name: comGC/cglC
• Type: Machinery gene
• Locus tag: R4713_RS04535
• Genome accession: NZ_CP137103
• Coordinates: 847231..847557 (-)
• Length: 108 a.a.
• NCBI ID: WP_000738650.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 21334
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 842231..852557

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4713_RS04490	rnpA	842255..842626 (-)	372	WP_000739246.1	ribonuclease P protein component	-
R4713_RS04495	-	842643..842774 (-)	132	WP_000768904.1	hypothetical protein	-
R4713_RS04500	-	842775..843965 (-)	1191	WP_081574829.1	acetate kinase	-
R4713_RS04505	comYH	844016..844969 (-)	954	WP_000345119.1	class I SAM-dependent methyltransferase	Machinery gene
R4713_RS04510	-	845030..845617 (-)	588	WP_000679774.1	class I SAM-dependent methyltransferase	-
R4713_RS04515	comGG/cglG	845754..846167 (-)	414	WP_000265630.1	competence type IV pilus minor pilin ComGG	Machinery gene
R4713_RS04520	comGF/cglF	846145..846606 (-)	462	WP_000250545.1	competence type IV pilus minor pilin ComGF	Machinery gene
R4713_RS04525	comGE/cglE	846569..846871 (-)	303	WP_000413380.1	competence type IV pilus minor pilin ComGE	Machinery gene
R4713_RS04530	comGD/cglD	846834..847238 (-)	405	WP_000588005.1	competence type IV pilus minor pilin ComGD	Machinery gene
R4713_RS04535	comGC/cglC	847231..847557 (-)	327	WP_000738650.1	comG operon protein ComGC	Machinery gene
R4713_RS04540	comGB/cglB	847559..848575 (-)	1017	WP_013193332.1	competence type IV pilus assembly protein ComGB	Machinery gene
R4713_RS04545	comGA/cglA/cilD	848523..849464 (-)	942	WP_000249567.1	competence type IV pilus ATPase ComGA	Machinery gene
R4713_RS04550	-	849540..849905 (-)	366	WP_000286415.1	DUF1033 family protein	-
R4713_RS04555	-	850056..851114 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-
R4713_RS04560	nagA	851277..852428 (-)	1152	WP_001134457.1	N-acetylglucosamine-6-phosphate deacetylase	-

Sequence

Protein

• Length: 108 a.a.
• Molecular weight: 12189.35 Da
• Isoelectric Point: 10.0523

>NTDB_id=895339 R4713_RS04535 WP_000738650.1 847231..847557(-) (comGC/cglC) [Streptococcus pneumoniae strain 21334]
MKKMMTFLKKSKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLQA
DGRITEEQAKAYKEYHDKNGVANRKVND

Nucleotide

• Length: 327 bp

>NTDB_id=895339 R4713_RS04535 WP_000738650.1 847231..847557(-) (comGC/cglC) [Streptococcus pneumoniae strain 21334]
ATGAAAAAAATGATGACATTCTTGAAAAAATCTAAGGTTAAAGCTTTTACATTGGTGGAGATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAGGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGAAAAGAATGAAGATGCTAGCCTAAGCAAGTTACAAGCA
GATGGGCGAATCACGGAAGAACAGGCTAAAGCTTATAAAGAATACCATGATAAAAATGGAGTAGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (11-34)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC/cglC	Streptococcus pneumoniae Rx1	97.222	100	0.972
comGC/cglC	Streptococcus pneumoniae D39	97.222	100	0.972
comGC/cglC	Streptococcus pneumoniae R6	97.222	100	0.972
comGC/cglC	Streptococcus pneumoniae TIGR4	96.296	100	0.963
comGC/cglC	Streptococcus mitis SK321	93.519	100	0.935
comGC/cglC	Streptococcus mitis NCTC 12261	92.157	94.444	0.87
comYC	Streptococcus gordonii str. Challis substr. CH1	72.917	88.889	0.648
comYC	Streptococcus mutans UA140	63.725	94.444	0.602
comYC	Streptococcus mutans UA159	63.725	94.444	0.602
comYC	Streptococcus suis isolate S10	70.37	75	0.528
comGC	Lactococcus lactis subsp. cremoris KW2	54.902	94.444	0.519
comGC	Staphylococcus aureus MW2	50	79.63	0.398
comGC	Staphylococcus aureus N315	50	79.63	0.398
comGC	Latilactobacillus sakei subsp. sakei 23K	45.349	79.63	0.361