Detailed information NTG0714985

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: NQZ90_RS00720
• Genome accession: NZ_CP102148
• Coordinates: 117664..117945 (+)
• Length: 93 a.a.
• NCBI ID: WP_141599722.1
• Uniprot ID: A0A540U443
• Organism: Streptococcus suis strain DNC15
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 112664..122945

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NQZ90_RS00695 (NQZ90_00695)	-	112848..114104 (-)	1257	WP_172063023.1	ISL3 family transposase	-
NQZ90_RS00700 (NQZ90_00700)	-	114327..114692 (+)	366	WP_014637310.1	DUF1033 family protein	-
NQZ90_RS00705 (NQZ90_00705)	-	114727..115677 (-)	951	WP_014637311.1	S66 peptidase family protein	-
NQZ90_RS00710 (NQZ90_00710)	comYA	115763..116713 (+)	951	WP_203200325.1	competence type IV pilus ATPase ComGA	Machinery gene
NQZ90_RS00715 (NQZ90_00715)	comYB	116625..117662 (+)	1038	WP_257110428.1	competence type IV pilus assembly protein ComGB	Machinery gene
NQZ90_RS00720 (NQZ90_00720)	comYC	117664..117945 (+)	282	WP_141599722.1	competence type IV pilus major pilin ComGC	Machinery gene
NQZ90_RS00725 (NQZ90_00725)	comGD	117926..118333 (+)	408	WP_141599724.1	competence type IV pilus minor pilin ComGD	-
NQZ90_RS00730 (NQZ90_00730)	comYE	118305..118598 (+)	294	WP_024405248.1	competence type IV pilus minor pilin ComGE	Machinery gene
NQZ90_RS00735 (NQZ90_00735)	comGF/cglF	118585..119019 (+)	435	WP_141599726.1	competence type IV pilus minor pilin ComGF	Machinery gene
NQZ90_RS00740 (NQZ90_00740)	comGG	118997..119407 (+)	411	WP_024415503.1	competence type IV pilus minor pilin ComGG	-
NQZ90_RS00745 (NQZ90_00745)	comYH	119464..120417 (+)	954	WP_141599728.1	class I SAM-dependent methyltransferase	Machinery gene
NQZ90_RS00750 (NQZ90_00750)	-	120467..121654 (+)	1188	WP_013730078.1	acetate kinase	-
NQZ90_RS00755 (NQZ90_00755)	-	121968..122519 (+)	552	WP_257110272.1	folate family ECF transporter S component	-

Sequence

Protein

• Length: 93 a.a.
• Molecular weight: 10364.33 Da
• Isoelectric Point: 8.4284

>NTDB_id=714985 NQZ90_RS00720 WP_141599722.1 117664..117945(+) (comYC) [Streptococcus suis strain DNC15]
MKKLIEMKVKGFTLVEMLVVLGIISLLLLLFVPNLSQQKDAIQKKGDAAVVKVVESQMELYELEHDKEATVADLQAAGYI
TEKQAKQYATAKK

Nucleotide

• Length: 282 bp

>NTDB_id=714985 NQZ90_RS00720 WP_141599722.1 117664..117945(+) (comYC) [Streptococcus suis strain DNC15]
ATGAAAAAGTTAATTGAAATGAAGGTAAAAGGGTTCACTCTGGTGGAAATGTTAGTCGTTTTGGGGATCATTAGCCTGCT
CTTGCTCCTTTTTGTGCCAAATTTGAGCCAGCAGAAGGATGCTATTCAGAAGAAGGGGGATGCGGCTGTTGTCAAAGTAG
TGGAGAGCCAGATGGAGCTCTATGAATTGGAACATGACAAGGAAGCAACGGTGGCAGACTTGCAGGCAGCTGGCTACATC
ACTGAAAAACAAGCAAAACAGTATGCTACGGCGAAAAAATAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (8-30)

3D structure

• AlphaFold DB: A0A540U443

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus suis isolate S10	96.774	100	0.968
comGC/cglC	Streptococcus pneumoniae TIGR4	64.13	98.925	0.634
comGC/cglC	Streptococcus pneumoniae Rx1	64.13	98.925	0.634
comGC/cglC	Streptococcus pneumoniae D39	64.13	98.925	0.634
comGC/cglC	Streptococcus pneumoniae R6	64.13	98.925	0.634
comGC/cglC	Streptococcus mitis SK321	64.13	98.925	0.634
comGC/cglC	Streptococcus mitis NCTC 12261	64.13	98.925	0.634
comYC	Streptococcus gordonii str. Challis substr. CH1	62.921	95.699	0.602
comYC	Streptococcus mutans UA140	60.227	94.624	0.57
comYC	Streptococcus mutans UA159	60.227	94.624	0.57
comGC	Lactococcus lactis subsp. cremoris KW2	57.955	94.624	0.548
comGC	Staphylococcus aureus MW2	50	83.871	0.419
comGC	Staphylococcus aureus N315	50	83.871	0.419
comGC	Bacillus subtilis subsp. subtilis str. 168	49.333	80.645	0.398