Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYE   Type   Machinery gene
Locus tag   NQZ90_RS00730 Genome accession   NZ_CP102148
Coordinates   118305..118598 (+) Length   97 a.a.
NCBI ID   WP_024405248.1    Uniprot ID   A0A4V0DNI2
Organism   Streptococcus suis strain DNC15     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 113305..123598
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NQZ90_RS00700 (NQZ90_00700) - 114327..114692 (+) 366 WP_014637310.1 DUF1033 family protein -
  NQZ90_RS00705 (NQZ90_00705) - 114727..115677 (-) 951 WP_014637311.1 S66 peptidase family protein -
  NQZ90_RS00710 (NQZ90_00710) comYA 115763..116713 (+) 951 WP_203200325.1 competence type IV pilus ATPase ComGA Machinery gene
  NQZ90_RS00715 (NQZ90_00715) comYB 116625..117662 (+) 1038 WP_257110428.1 competence type IV pilus assembly protein ComGB Machinery gene
  NQZ90_RS00720 (NQZ90_00720) comYC 117664..117945 (+) 282 WP_141599722.1 competence type IV pilus major pilin ComGC Machinery gene
  NQZ90_RS00725 (NQZ90_00725) comGD 117926..118333 (+) 408 WP_141599724.1 competence type IV pilus minor pilin ComGD -
  NQZ90_RS00730 (NQZ90_00730) comYE 118305..118598 (+) 294 WP_024405248.1 competence type IV pilus minor pilin ComGE Machinery gene
  NQZ90_RS00735 (NQZ90_00735) comGF/cglF 118585..119019 (+) 435 WP_141599726.1 competence type IV pilus minor pilin ComGF Machinery gene
  NQZ90_RS00740 (NQZ90_00740) comGG 118997..119407 (+) 411 WP_024415503.1 competence type IV pilus minor pilin ComGG -
  NQZ90_RS00745 (NQZ90_00745) comYH 119464..120417 (+) 954 WP_141599728.1 class I SAM-dependent methyltransferase Machinery gene
  NQZ90_RS00750 (NQZ90_00750) - 120467..121654 (+) 1188 WP_013730078.1 acetate kinase -
  NQZ90_RS00755 (NQZ90_00755) - 121968..122519 (+) 552 WP_257110272.1 folate family ECF transporter S component -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10771.63 Da        Isoelectric Point: 9.0978

>NTDB_id=714986 NQZ90_RS00730 WP_024405248.1 118305..118598(+) (comYE) [Streptococcus suis strain DNC15]
MVAIRKQKNKAYILLESLVALATLVTICSLILSAVDAGRRRQDWELEQQEVLNLAQMAVQTGQDNLALNGVTVQVQRTAD
KIIVFHEGKEVLSVVKK

Nucleotide


Download         Length: 294 bp        

>NTDB_id=714986 NQZ90_RS00730 WP_024405248.1 118305..118598(+) (comYE) [Streptococcus suis strain DNC15]
GTGGTCGCTATAAGAAAACAGAAGAATAAGGCTTATATTTTATTAGAAAGTTTGGTAGCCCTAGCTACCTTGGTGACCAT
TTGTAGCTTGATTTTGTCAGCGGTGGATGCTGGTCGTAGGCGACAGGATTGGGAATTGGAACAACAGGAGGTTCTCAATC
TAGCACAGATGGCTGTTCAGACCGGGCAAGATAACCTAGCCTTAAACGGTGTTACAGTTCAGGTTCAACGAACTGCGGAT
AAGATTATTGTTTTCCACGAGGGAAAGGAGGTTTTATCGGTTGTTAAAAAGTAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4V0DNI2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYE Streptococcus mutans UA140

53.608

100

0.536
  comYE Streptococcus mutans UA159

53.608

100

0.536
  comGE/cglE Streptococcus pneumoniae Rx1

40.217

94.845

0.381
  comGE/cglE Streptococcus pneumoniae D39

40.217

94.845

0.381
  comGE/cglE Streptococcus pneumoniae R6

40.217

94.845

0.381
  comGE/cglE Streptococcus pneumoniae TIGR4

40.217

94.845

0.381
  comGE/cglE Streptococcus mitis SK321

39.13

94.845

0.371
  comGE/cglE Streptococcus mitis NCTC 12261

39.13

94.845

0.371