Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraS   Type   Regulator
Locus tag   K8B68_RS09060 Genome accession   NZ_CP082813
Coordinates   1879460..1880503 (-) Length   347 a.a.
NCBI ID   WP_001017131.1    Uniprot ID   A0A0D1IMN4
Organism   Staphylococcus aureus strain SCAID OTT1-2021 (597/2)     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1874460..1885503
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K8B68_RS09030 (K8B68_09030) - 1874881..1876128 (-) 1248 WP_000656302.1 aminopeptidase -
  K8B68_RS09035 (K8B68_09035) - 1876140..1876340 (-) 201 WP_000180459.1 DUF1128 family protein -
  K8B68_RS09040 (K8B68_09040) - 1876487..1876951 (+) 465 WP_000228668.1 low molecular weight protein-tyrosine-phosphatase -
  K8B68_RS09045 (K8B68_09045) - 1876958..1877233 (+) 276 WP_000428172.1 YtxH domain-containing protein -
  K8B68_RS09050 (K8B68_09050) - 1877511..1878728 (+) 1218 WP_000037083.1 YihY/virulence factor BrkB family protein -
  K8B68_RS09055 (K8B68_09055) vraR 1878841..1879470 (-) 630 WP_000153535.1 two-component system response regulator VraR Regulator
  K8B68_RS09060 (K8B68_09060) vraS 1879460..1880503 (-) 1044 WP_001017131.1 sensor histidine kinase Regulator
  K8B68_RS09065 (K8B68_09065) liaF 1880500..1881201 (-) 702 WP_000149064.1 cell wall-active antibiotics response protein LiaF -
  K8B68_RS09070 (K8B68_09070) - 1881216..1881602 (-) 387 WP_001110184.1 hypothetical protein -
  K8B68_RS09075 (K8B68_09075) map 1881819..1882577 (-) 759 WP_000636137.1 type I methionyl aminopeptidase -
  K8B68_RS09080 (K8B68_09080) - 1883108..1884094 (+) 987 WP_000999713.1 FUSC family protein -
  K8B68_RS09085 (K8B68_09085) - 1884272..1884685 (-) 414 WP_001622129.1 hypothetical protein -
  K8B68_RS09090 (K8B68_09090) - 1884714..1884823 (-) 110 Protein_1758 hypothetical protein -

Sequence

Protein


Download         Length: 347 a.a.        Molecular weight: 40044.52 Da        Isoelectric Point: 6.0577

>NTDB_id=602464 K8B68_RS09060 WP_001017131.1 1879460..1880503(-) (vraS) [Staphylococcus aureus strain SCAID OTT1-2021 (597/2)]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide


Download         Length: 1044 bp        

>NTDB_id=602464 K8B68_RS09060 WP_001017131.1 1879460..1880503(-) (vraS) [Staphylococcus aureus strain SCAID OTT1-2021 (597/2)]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTACCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTCGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(249-340)

Histidine kinase (HisKA_3)

(147-210)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0D1IMN4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraS Staphylococcus aureus N315

100

100

1