Detailed information NTG0516961

Bioinformatically predicted

Overview

• Name: comGC/cglC
• Type: Machinery gene
• Locus tag: I6H78_RS04485
• Genome accession: NZ_CP066059
• Coordinates: 931987..932310 (-)
• Length: 107 a.a.
• NCBI ID: WP_000735798.1
• Uniprot ID: A0A1X1HB54
• Organism: Streptococcus oralis strain FDAARGOS_1021
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 926987..937310

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6H78_RS04445 (I6H78_04445)	rnpA	927113..927484 (-)	372	WP_000748120.1	ribonuclease P protein component	-
I6H78_RS04450 (I6H78_04450)	-	927634..928824 (-)	1191	WP_198460190.1	acetate kinase	-
I6H78_RS04455 (I6H78_04455)	comYH	928875..929828 (-)	954	WP_198460191.1	class I SAM-dependent methyltransferase	Machinery gene
I6H78_RS04460 (I6H78_04460)	-	929887..930477 (-)	591	WP_198460192.1	class I SAM-dependent methyltransferase	-
I6H78_RS04465 (I6H78_04465)	comGG/cglG	930510..930923 (-)	414	WP_000265643.1	competence type IV pilus minor pilin ComGG	Machinery gene
I6H78_RS04470 (I6H78_04470)	comGF/cglF	930901..931362 (-)	462	WP_000250706.1	competence type IV pilus minor pilin ComGF	Machinery gene
I6H78_RS04475 (I6H78_04475)	comGE/cglE	931325..931627 (-)	303	WP_000413374.1	competence type IV pilus minor pilin ComGE	Machinery gene
I6H78_RS04480 (I6H78_04480)	comGD/cglD	931590..932024 (-)	435	WP_198460193.1	competence type IV pilus minor pilin ComGD	Machinery gene
I6H78_RS04485 (I6H78_04485)	comGC/cglC	931987..932310 (-)	324	WP_000735798.1	competence type IV pilus major pilin ComGC	Machinery gene
I6H78_RS04490 (I6H78_04490)	comGB/cglB	932312..933328 (-)	1017	WP_198460227.1	competence type IV pilus assembly protein ComGB	Machinery gene
I6H78_RS04495 (I6H78_04495)	comGA/cglA/cilD	933276..934217 (-)	942	WP_198460194.1	competence type IV pilus ATPase ComGA	Machinery gene
I6H78_RS04500 (I6H78_04500)	-	934280..934645 (-)	366	WP_000286396.1	DUF1033 family protein	-
I6H78_RS04505 (I6H78_04505)	nagA	934798..935949 (-)	1152	WP_198460195.1	N-acetylglucosamine-6-phosphate deacetylase	-

Sequence

Protein

• Length: 107 a.a.
• Molecular weight: 11891.03 Da
• Isoelectric Point: 10.1883

>NTDB_id=516961 I6H78_RS04485 WP_000735798.1 931987..932310(-) (comGC/cglC) [Streptococcus oralis strain FDAARGOS_1021]
MKKLMTNLKKAKVKAFTLVEMLVVLLIISVLLLLFVPNLTKQKDAVDDKGKAAVVKVVESQAELYRLDKNDDASLSKLQA
DGRITAEQAKAYKDYHAKQKTSQTVAD

Nucleotide

• Length: 324 bp

>NTDB_id=516961 I6H78_RS04485 WP_000735798.1 931987..932310(-) (comGC/cglC) [Streptococcus oralis strain FDAARGOS_1021]
ATGAAAAAACTCATGACAAATTTAAAAAAAGCCAAGGTTAAAGCTTTCACTTTGGTAGAAATGTTAGTGGTTTTGCTTAT
CATCAGTGTTCTTCTCTTGCTCTTTGTGCCCAATTTGACCAAGCAAAAGGATGCCGTAGATGACAAAGGAAAAGCTGCTG
TTGTCAAGGTCGTGGAAAGCCAGGCAGAACTTTATCGTTTAGATAAAAATGATGACGCCAGCCTCAGCAAATTACAAGCG
GACGGTCGTATCACAGCTGAGCAAGCCAAAGCTTATAAAGACTACCATGCAAAACAAAAAACAAGTCAAACTGTTGCAGA
TTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (11-34)

3D structure

• AlphaFold DB: A0A1X1HB54

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC/cglC	Streptococcus mitis NCTC 12261	91.589	100	0.916
comGC/cglC	Streptococcus mitis SK321	88.889	92.523	0.822
comGC/cglC	Streptococcus pneumoniae R6	86.869	92.523	0.804
comGC/cglC	Streptococcus pneumoniae Rx1	86.869	92.523	0.804
comGC/cglC	Streptococcus pneumoniae D39	86.869	92.523	0.804
comGC/cglC	Streptococcus pneumoniae TIGR4	85.859	92.523	0.794
comYC	Streptococcus gordonii str. Challis substr. CH1	67.619	98.131	0.664
comYC	Streptococcus mutans UA140	70.103	90.654	0.636
comYC	Streptococcus mutans UA159	70.103	90.654	0.636
comGC	Lactococcus lactis subsp. cremoris KW2	57.426	94.393	0.542
comYC	Streptococcus suis isolate S10	65.909	82.243	0.542