Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   I6H78_RS04475 Genome accession   NZ_CP066059
Coordinates   931325..931627 (-) Length   100 a.a.
NCBI ID   WP_000413374.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_1021     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 926325..936627
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H78_RS04445 (I6H78_04445) rnpA 927113..927484 (-) 372 WP_000748120.1 ribonuclease P protein component -
  I6H78_RS04450 (I6H78_04450) - 927634..928824 (-) 1191 WP_198460190.1 acetate kinase -
  I6H78_RS04455 (I6H78_04455) comYH 928875..929828 (-) 954 WP_198460191.1 class I SAM-dependent methyltransferase Machinery gene
  I6H78_RS04460 (I6H78_04460) - 929887..930477 (-) 591 WP_198460192.1 class I SAM-dependent methyltransferase -
  I6H78_RS04465 (I6H78_04465) comGG/cglG 930510..930923 (-) 414 WP_000265643.1 competence type IV pilus minor pilin ComGG Machinery gene
  I6H78_RS04470 (I6H78_04470) comGF/cglF 930901..931362 (-) 462 WP_000250706.1 competence type IV pilus minor pilin ComGF Machinery gene
  I6H78_RS04475 (I6H78_04475) comGE/cglE 931325..931627 (-) 303 WP_000413374.1 competence type IV pilus minor pilin ComGE Machinery gene
  I6H78_RS04480 (I6H78_04480) comGD/cglD 931590..932024 (-) 435 WP_198460193.1 competence type IV pilus minor pilin ComGD Machinery gene
  I6H78_RS04485 (I6H78_04485) comGC/cglC 931987..932310 (-) 324 WP_000735798.1 competence type IV pilus major pilin ComGC Machinery gene
  I6H78_RS04490 (I6H78_04490) comGB/cglB 932312..933328 (-) 1017 WP_198460227.1 competence type IV pilus assembly protein ComGB Machinery gene
  I6H78_RS04495 (I6H78_04495) comGA/cglA/cilD 933276..934217 (-) 942 WP_198460194.1 competence type IV pilus ATPase ComGA Machinery gene
  I6H78_RS04500 (I6H78_04500) - 934280..934645 (-) 366 WP_000286396.1 DUF1033 family protein -
  I6H78_RS04505 (I6H78_04505) nagA 934798..935949 (-) 1152 WP_198460195.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11122.06 Da        Isoelectric Point: 7.0157

>NTDB_id=516959 I6H78_RS04475 WP_000413374.1 931325..931627(-) (comGE/cglE) [Streptococcus oralis strain FDAARGOS_1021]
MEKLNALRKQKIKAVILLEAVVALAVFASIATLLLGQIQKNRQEEAEILQKEEVLRVAKMALQTGQNQVNINGVEIQVFA
SEKGLEVYHGSEKLLDLKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=516959 I6H78_RS04475 WP_000413374.1 931325..931627(-) (comGE/cglE) [Streptococcus oralis strain FDAARGOS_1021]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAAGGCAGTGATTTTACTGGAAGCGGTGGTTGCTCTAGCCGTTTT
TGCCAGCATTGCAACCCTCCTTTTAGGACAAATTCAGAAAAATAGACAAGAAGAGGCAGAAATCTTGCAAAAGGAAGAAG
TCTTGCGTGTGGCGAAGATGGCTCTGCAAACAGGGCAAAATCAAGTAAACATAAACGGAGTTGAGATTCAGGTATTTGCT
AGTGAAAAGGGATTGGAGGTCTACCATGGTTCAGAGAAGTTGCTCGACCTTAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-96)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus mitis NCTC 12261

92

100

0.92
  comGE/cglE Streptococcus pneumoniae Rx1

92

100

0.92
  comGE/cglE Streptococcus pneumoniae D39

92

100

0.92
  comGE/cglE Streptococcus pneumoniae R6

92

100

0.92
  comGE/cglE Streptococcus pneumoniae TIGR4

92

100

0.92
  comGE/cglE Streptococcus mitis SK321

91

100

0.91
  comYE Streptococcus mutans UA140

43.478

92

0.4
  comYE Streptococcus mutans UA159

43.478

92

0.4