Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   I6H78_RS04455 Genome accession   NZ_CP066059
Coordinates   928875..929828 (-) Length   317 a.a.
NCBI ID   WP_198460191.1    Uniprot ID   A0A7T4IUC8
Organism   Streptococcus oralis strain FDAARGOS_1021     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 923875..934828
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H78_RS04430 (I6H78_04430) - 924631..925254 (-) 624 WP_198460189.1 ribonuclease P -
  I6H78_RS04435 (I6H78_04435) jag 925310..926296 (-) 987 WP_042768792.1 RNA-binding cell elongation regulator Jag/EloR -
  I6H78_RS04440 (I6H78_04440) - 926311..927138 (-) 828 WP_162837252.1 membrane protein insertase YidC -
  I6H78_RS04445 (I6H78_04445) rnpA 927113..927484 (-) 372 WP_000748120.1 ribonuclease P protein component -
  I6H78_RS04450 (I6H78_04450) - 927634..928824 (-) 1191 WP_198460190.1 acetate kinase -
  I6H78_RS04455 (I6H78_04455) comYH 928875..929828 (-) 954 WP_198460191.1 class I SAM-dependent methyltransferase Machinery gene
  I6H78_RS04460 (I6H78_04460) - 929887..930477 (-) 591 WP_198460192.1 class I SAM-dependent methyltransferase -
  I6H78_RS04465 (I6H78_04465) comGG/cglG 930510..930923 (-) 414 WP_000265643.1 competence type IV pilus minor pilin ComGG Machinery gene
  I6H78_RS04470 (I6H78_04470) comGF/cglF 930901..931362 (-) 462 WP_000250706.1 competence type IV pilus minor pilin ComGF Machinery gene
  I6H78_RS04475 (I6H78_04475) comGE/cglE 931325..931627 (-) 303 WP_000413374.1 competence type IV pilus minor pilin ComGE Machinery gene
  I6H78_RS04480 (I6H78_04480) comGD/cglD 931590..932024 (-) 435 WP_198460193.1 competence type IV pilus minor pilin ComGD Machinery gene
  I6H78_RS04485 (I6H78_04485) comGC/cglC 931987..932310 (-) 324 WP_000735798.1 competence type IV pilus major pilin ComGC Machinery gene
  I6H78_RS04490 (I6H78_04490) comGB/cglB 932312..933328 (-) 1017 WP_198460227.1 competence type IV pilus assembly protein ComGB Machinery gene
  I6H78_RS04495 (I6H78_04495) comGA/cglA/cilD 933276..934217 (-) 942 WP_198460194.1 competence type IV pilus ATPase ComGA Machinery gene
  I6H78_RS04500 (I6H78_04500) - 934280..934645 (-) 366 WP_000286396.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35540.50 Da        Isoelectric Point: 4.1443

>NTDB_id=516956 I6H78_RS04455 WP_198460191.1 928875..929828(-) (comYH) [Streptococcus oralis strain FDAARGOS_1021]
MDFEKIEQAYTYLLENVQAIQSDLATNFYDALVEQNSIYLDGETELEQVKENNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAISLLLVLIVEELFEQEEISILEIGSGMGILGATFLTSLAKKVDYLGIEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAIASRYQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKGWLKDEVSLAAIIALPEDIFSTASQAKSIFVLQKKRDKEIEPFVYPLTSLQDPSVLLTFKENFQNWSKGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=516956 I6H78_RS04455 WP_198460191.1 928875..929828(-) (comYH) [Streptococcus oralis strain FDAARGOS_1021]
ATGGATTTTGAAAAAATAGAACAAGCTTATACGTATTTACTAGAGAATGTCCAAGCCATTCAAAGTGATTTGGCGACCAA
CTTTTATGATGCCTTGGTAGAGCAAAATAGTATCTACCTAGATGGCGAGACCGAACTAGAGCAGGTCAAGGAGAACAATC
AAGCCCTTAAACGCTTAGCACTTCGCAAAGAAGAATGGCTCAAGACCTATCAGTTTCTCTTGATGAAGGCAGGACAAACG
GAGCCTTTACAGGCCAATCACCAGTTTACACCAGATGCCATTTCCCTCCTATTGGTACTCATTGTGGAAGAGTTGTTTGA
ACAAGAGGAAATTAGCATCCTCGAAATAGGTTCTGGTATGGGGATTTTGGGGGCTACTTTCTTGACTTCTCTCGCTAAAA
AAGTAGATTACTTGGGAATCGAAGTGGATGACTTGCTGATTGATTTGGCAGCCAGTATGGCAGATGTGATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGACGCCGTTCGTCCGCAAATGCTTAAAGAAAGCGACGTGGTCATCAGCGACTTGCCTGTAGG
CTATTACCCAGACGATGCCATCGCTTCACGCTATCAAGTGGCTTCTAGTCAAGAGCATACCTATGCCCACCATTTACTGA
TGGAACAAGGCCTCAAGTACCTTAAGTCAGATGGCTATGCTATTTTTCTAGCTCCGAGTGATTTATTGACCAGTCCTCAA
AGTGATTTATTAAAAGGGTGGCTCAAAGACGAAGTAAGTCTGGCTGCTATCATCGCTCTGCCAGAGGATATTTTCTCAAC
TGCAAGCCAAGCTAAAAGTATTTTTGTCTTACAGAAGAAAAGAGACAAGGAAATAGAACCCTTTGTCTACCCTCTTACTA
GCTTGCAAGATCCGTCAGTTTTGTTGACCTTTAAAGAAAATTTTCAAAATTGGAGCAAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-283)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7T4IUC8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

58.199

98.107

0.571
  comYH Streptococcus mutans UA159

57.878

98.107

0.568