Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   SPNINV200_RS10045 Genome accession   NC_017593
Coordinates   1887590..1887916 (-) Length   108 a.a.
NCBI ID   WP_000738623.1    Uniprot ID   -
Organism   Streptococcus pneumoniae INV200     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1882590..1892916
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPNINV200_RS10000 (SPNINV200_18560) rnpA 1882615..1882986 (-) 372 WP_000739246.1 ribonuclease P protein component -
  SPNINV200_RS10005 (SPNINV200_18570) - 1883134..1884324 (-) 1191 WP_000167755.1 acetate kinase -
  SPNINV200_RS10010 (SPNINV200_18580) comYH 1884375..1885328 (-) 954 WP_000345084.1 class I SAM-dependent methyltransferase Machinery gene
  SPNINV200_RS12560 (SPNINV200_18590) - 1885389..1885976 (-) 588 Protein_1863 class I SAM-dependent methyltransferase -
  SPNINV200_RS10025 (SPNINV200_18600) comGG/cglG 1886113..1886526 (-) 414 WP_000265617.1 competence type IV pilus minor pilin ComGG Machinery gene
  SPNINV200_RS10030 (SPNINV200_18610) comGF/cglF 1886504..1886965 (-) 462 WP_000250529.1 competence type IV pilus minor pilin ComGF Machinery gene
  SPNINV200_RS10035 (SPNINV200_18620) comGE/cglE 1886928..1887230 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  SPNINV200_RS10040 (SPNINV200_18630) comGD/cglD 1887193..1887597 (-) 405 WP_000588002.1 competence type IV pilus minor pilin ComGD Machinery gene
  SPNINV200_RS10045 (SPNINV200_18640) comGC/cglC 1887590..1887916 (-) 327 WP_000738623.1 comG operon protein ComGC Machinery gene
  SPNINV200_RS10050 (SPNINV200_18650) comGB/cglB 1887918..1888934 (-) 1017 WP_077141332.1 competence type IV pilus assembly protein ComGB Machinery gene
  SPNINV200_RS10055 (SPNINV200_18660) comGA/cglA/cilD 1888882..1889823 (-) 942 WP_000249550.1 competence type IV pilus ATPase ComGA Machinery gene
  SPNINV200_RS10060 (SPNINV200_18670) - 1889899..1890264 (-) 366 WP_000286415.1 DUF1033 family protein -
  SPNINV200_RS10065 (SPNINV200_18680) - 1890415..1891473 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  SPNINV200_RS10070 (SPNINV200_18690) nagA 1891636..1892787 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12187.38 Da        Isoelectric Point: 10.0523

>NTDB_id=49351 SPNINV200_RS10045 WP_000738623.1 1887590..1887916(-) (comGC/cglC) [Streptococcus pneumoniae INV200]
MKKMMTFLKKAKVKAFTLIEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLQA
DGRITEEQAKAYKEYHDKNGVANRKVND

Nucleotide


Download         Length: 327 bp        

>NTDB_id=49351 SPNINV200_RS10045 WP_000738623.1 1887590..1887916(-) (comGC/cglC) [Streptococcus pneumoniae INV200]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGATTGAGATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAGGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGAAAAGAATGAAGATGCTAGCCTAAGCAAGTTACAAGCA
GATGGGCGAATCACGGAAGAACAGGCTAAAGCTTATAAAGAATACCATGATAAAAATGGAGTAGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus pneumoniae Rx1

97.222

100

0.972
  comGC/cglC Streptococcus pneumoniae D39

97.222

100

0.972
  comGC/cglC Streptococcus pneumoniae R6

97.222

100

0.972
  comGC/cglC Streptococcus pneumoniae TIGR4

96.296

100

0.963
  comGC/cglC Streptococcus mitis SK321

93.519

100

0.935
  comGC/cglC Streptococcus mitis NCTC 12261

92.157

94.444

0.87
  comYC Streptococcus gordonii str. Challis substr. CH1

71.875

88.889

0.639
  comYC Streptococcus mutans UA159

64.706

94.444

0.611
  comYC Streptococcus mutans UA140

64.706

94.444

0.611
  comGC Lactococcus lactis subsp. cremoris KW2

55.882

94.444

0.528
  comYC Streptococcus suis isolate S10

69.136

75

0.519
  comGC Staphylococcus aureus MW2

51.163

79.63

0.407
  comGC Staphylococcus aureus N315

51.163

79.63

0.407
  comGC Latilactobacillus sakei subsp. sakei 23K

46.512

79.63

0.37

Multiple sequence alignment