Detailed information NTG0049349

Bioinformatically predicted

Overview

• Name: comGE/cglE
• Type: Machinery gene
• Locus tag: SPNINV200_RS10035
• Genome accession: NC_017593
• Coordinates: 1886928..1887230 (-)
• Length: 100 a.a.
• NCBI ID: WP_000413382.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae INV200
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1881928..1892230

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPNINV200_RS10000 (SPNINV200_18560)	rnpA	1882615..1882986 (-)	372	WP_000739246.1	ribonuclease P protein component	-
SPNINV200_RS10005 (SPNINV200_18570)	-	1883134..1884324 (-)	1191	WP_000167755.1	acetate kinase	-
SPNINV200_RS10010 (SPNINV200_18580)	comYH	1884375..1885328 (-)	954	WP_000345084.1	class I SAM-dependent methyltransferase	Machinery gene
SPNINV200_RS12560 (SPNINV200_18590)	-	1885389..1885976 (-)	588	Protein_1863	class I SAM-dependent methyltransferase	-
SPNINV200_RS10025 (SPNINV200_18600)	comGG/cglG	1886113..1886526 (-)	414	WP_000265617.1	competence type IV pilus minor pilin ComGG	Machinery gene
SPNINV200_RS10030 (SPNINV200_18610)	comGF/cglF	1886504..1886965 (-)	462	WP_000250529.1	competence type IV pilus minor pilin ComGF	Machinery gene
SPNINV200_RS10035 (SPNINV200_18620)	comGE/cglE	1886928..1887230 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
SPNINV200_RS10040 (SPNINV200_18630)	comGD/cglD	1887193..1887597 (-)	405	WP_000588002.1	competence type IV pilus minor pilin ComGD	Machinery gene
SPNINV200_RS10045 (SPNINV200_18640)	comGC/cglC	1887590..1887916 (-)	327	WP_000738623.1	comG operon protein ComGC	Machinery gene
SPNINV200_RS10050 (SPNINV200_18650)	comGB/cglB	1887918..1888934 (-)	1017	WP_077141332.1	competence type IV pilus assembly protein ComGB	Machinery gene
SPNINV200_RS10055 (SPNINV200_18660)	comGA/cglA/cilD	1888882..1889823 (-)	942	WP_000249550.1	competence type IV pilus ATPase ComGA	Machinery gene
SPNINV200_RS10060 (SPNINV200_18670)	-	1889899..1890264 (-)	366	WP_000286415.1	DUF1033 family protein	-
SPNINV200_RS10065 (SPNINV200_18680)	-	1890415..1891473 (-)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 100 a.a.
• Molecular weight: 11108.08 Da
• Isoelectric Point: 9.7273

>NTDB_id=49349 SPNINV200_RS10035 WP_000413382.1 1886928..1887230(-) (comGE/cglE) [Streptococcus pneumoniae INV200]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide

• Length: 303 bp

>NTDB_id=49349 SPNINV200_RS10035 WP_000413382.1 1886928..1887230(-) (comGE/cglE) [Streptococcus pneumoniae INV200]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

• Type II secretory pathway pseudopilin (ComGE) (16-97)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGE/cglE	Streptococcus pneumoniae Rx1	100	100	1
comGE/cglE	Streptococcus pneumoniae D39	100	100	1
comGE/cglE	Streptococcus pneumoniae R6	100	100	1
comGE/cglE	Streptococcus pneumoniae TIGR4	100	100	1
comGE/cglE	Streptococcus mitis NCTC 12261	98	100	0.98
comGE/cglE	Streptococcus mitis SK321	98	100	0.98
comYE	Streptococcus mutans UA140	44.444	90	0.4
comYE	Streptococcus mutans UA159	44.444	90	0.4