Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   JJW05_RS15425 Genome accession   NZ_CP068279
Coordinates   3150692..3151348 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain CY708     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3145692..3156348
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JJW05_RS15395 (JJW05_15305) yecA 3146943..3147608 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  JJW05_RS15415 (JJW05_15325) pgsA 3148258..3148806 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  JJW05_RS15420 (JJW05_15330) uvrC 3148863..3150695 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  JJW05_RS15425 (JJW05_15335) letA 3150692..3151348 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  JJW05_RS23110 - 3151490..3151561 (+) 72 Protein_3034 transcriptional regulator -
  JJW05_RS15430 (JJW05_15340) yecU 3151644..3151820 (+) 177 WP_000590347.1 protein YecU -
  JJW05_RS15435 (JJW05_15345) yecF 3151807..3152031 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  JJW05_RS15440 (JJW05_15350) sdiA 3152099..3152821 (-) 723 WP_001152715.1 transcriptional regulator SdiA -
  JJW05_RS15445 (JJW05_15355) tcyN 3153051..3153803 (-) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  JJW05_RS15450 (JJW05_15360) tcyL 3153800..3154468 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  JJW05_RS15455 (JJW05_15365) dcyD 3154483..3155469 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=459440 JJW05_RS15425 WP_000611335.1 3150692..3151348(-) (letA) [Escherichia coli strain CY708]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=459440 JJW05_RS15425 WP_000611335.1 3150692..3151348(-) (letA) [Escherichia coli strain CY708]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486