Detailed information NTG0042035

Bioinformatically predicted

Overview

• Name: comGC/cglC
• Type: Machinery gene
• Locus tag: SPPN_RS10350
• Genome accession: NC_015875
• Coordinates: 1982799..1983122 (-)
• Length: 107 a.a.
• NCBI ID: WP_000738647.1
• Uniprot ID: -
• Organism: Streptococcus pseudopneumoniae IS7493
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1977799..1988122

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPPN_RS10315 (SPPN_10440)	-	1978030..1979232 (+)	1203	WP_000855226.1	ATP-grasp domain-containing protein	-
SPPN_RS10320 (SPPN_10445)	-	1979345..1979821 (+)	477	WP_000777684.1	GNAT family N-acetyltransferase	-
SPPN_RS10325 (SPPN_10450)	-	1980018..1980860 (+)	843	WP_000840058.1	helix-turn-helix domain-containing protein	-
SPPN_RS10330 (SPPN_10455)	comGG/cglG	1981322..1981735 (-)	414	WP_000265635.1	competence type IV pilus minor pilin ComGG	Machinery gene
SPPN_RS10335 (SPPN_10460)	comGF/cglF	1981713..1982174 (-)	462	WP_000250511.1	competence type IV pilus minor pilin ComGF	Machinery gene
SPPN_RS10340 (SPPN_10465)	comGE/cglE	1982137..1982439 (-)	303	WP_000413380.1	competence type IV pilus minor pilin ComGE	Machinery gene
SPPN_RS10345 (SPPN_10470)	comGD/cglD	1982402..1982836 (-)	435	WP_044012294.1	competence type IV pilus minor pilin ComGD	Machinery gene
SPPN_RS10350 (SPPN_10475)	comGC/cglC	1982799..1983122 (-)	324	WP_000738647.1	comG operon protein ComGC	Machinery gene
SPPN_RS10355 (SPPN_10480)	comGB/cglB	1983124..1984140 (-)	1017	WP_080564700.1	competence type IV pilus assembly protein ComGB	Machinery gene
SPPN_RS10360 (SPPN_10485)	comGA/cglA/cilD	1984088..1985029 (-)	942	WP_000249547.1	competence type IV pilus ATPase ComGA	Machinery gene
SPPN_RS10365 (SPPN_10490)	-	1985105..1985470 (-)	366	WP_000286407.1	DUF1033 family protein	-
SPPN_RS10370 (SPPN_10495)	-	1985621..1986658 (-)	1038	Protein_2082	zinc-dependent alcohol dehydrogenase family protein	-
SPPN_RS10375 (SPPN_10500)	-	1986977..1987216 (-)	240	WP_000907298.1	hypothetical protein	-
SPPN_RS10380 (SPPN_10505)	-	1987330..1987764 (-)	435	WP_000355912.1	cytidine deaminase family protein	-

Sequence

Protein

• Length: 107 a.a.
• Molecular weight: 12070.27 Da
• Isoelectric Point: 10.0527

>NTDB_id=42035 SPPN_RS10350 WP_000738647.1 1982799..1983122(-) (comGC/cglC) [Streptococcus pseudopneumoniae IS7493]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLLLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLQA
NDRITEEQAKAYKEYHAKQNKTQTVAD

Nucleotide

• Length: 324 bp

>NTDB_id=42035 SPPN_RS10350 WP_000738647.1 1982799..1983122(-) (comGC/cglC) [Streptococcus pseudopneumoniae IS7493]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACACTTGTGGAGATGTTGGTGGTCTTGCTCAT
CATCAGCGTGCTTCTATTACTCTTTGTACCAAATTTGACCAAGCAAAAAGAGGCTGTCAATGATAAAGGAAAAGCTGCTG
TTGTTAAGGTAGTGGAAAGCCAGGCAGAGCTTTATAGCTTAGAAAAAAATGAAGATGCTAGCCTAAGCAAATTACAAGCA
AATGATCGAATCACAGAAGAGCAAGCTAAAGCTTATAAAGAATATCATGCAAAACAAAATAAGACTCAAACCGTTGCAGA
TTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (11-34)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC/cglC	Streptococcus mitis NCTC 12261	95.327	100	0.953
comGC/cglC	Streptococcus pneumoniae Rx1	93	93.458	0.869
comGC/cglC	Streptococcus pneumoniae D39	93	93.458	0.869
comGC/cglC	Streptococcus pneumoniae R6	93	93.458	0.869
comGC/cglC	Streptococcus mitis SK321	93	93.458	0.869
comGC/cglC	Streptococcus pneumoniae TIGR4	92	93.458	0.86
comYC	Streptococcus gordonii str. Challis substr. CH1	69.524	98.131	0.682
comYC	Streptococcus mutans UA140	65.385	97.196	0.636
comYC	Streptococcus mutans UA159	65.385	97.196	0.636
comYC	Streptococcus suis isolate S10	70.37	75.701	0.533
comGC	Lactococcus lactis subsp. cremoris KW2	55.67	90.654	0.505
comGC	Staphylococcus aureus MW2	48.837	80.374	0.393
comGC	Staphylococcus aureus N315	48.837	80.374	0.393