Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   SPPN_RS10355 Genome accession   NC_015875
Coordinates   1983124..1984140 (-) Length   338 a.a.
NCBI ID   WP_080564700.1    Uniprot ID   -
Organism   Streptococcus pseudopneumoniae IS7493     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1978124..1989140
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPPN_RS10320 (SPPN_10445) - 1979345..1979821 (+) 477 WP_000777684.1 GNAT family N-acetyltransferase -
  SPPN_RS10325 (SPPN_10450) - 1980018..1980860 (+) 843 WP_000840058.1 helix-turn-helix domain-containing protein -
  SPPN_RS10330 (SPPN_10455) comGG/cglG 1981322..1981735 (-) 414 WP_000265635.1 competence type IV pilus minor pilin ComGG Machinery gene
  SPPN_RS10335 (SPPN_10460) comGF/cglF 1981713..1982174 (-) 462 WP_000250511.1 competence type IV pilus minor pilin ComGF Machinery gene
  SPPN_RS10340 (SPPN_10465) comGE/cglE 1982137..1982439 (-) 303 WP_000413380.1 competence type IV pilus minor pilin ComGE Machinery gene
  SPPN_RS10345 (SPPN_10470) comGD/cglD 1982402..1982836 (-) 435 WP_044012294.1 competence type IV pilus minor pilin ComGD Machinery gene
  SPPN_RS10350 (SPPN_10475) comGC/cglC 1982799..1983122 (-) 324 WP_000738647.1 comG operon protein ComGC Machinery gene
  SPPN_RS10355 (SPPN_10480) comGB/cglB 1983124..1984140 (-) 1017 WP_080564700.1 competence type IV pilus assembly protein ComGB Machinery gene
  SPPN_RS10360 (SPPN_10485) comGA/cglA/cilD 1984088..1985029 (-) 942 WP_000249547.1 competence type IV pilus ATPase ComGA Machinery gene
  SPPN_RS10365 (SPPN_10490) - 1985105..1985470 (-) 366 WP_000286407.1 DUF1033 family protein -
  SPPN_RS10370 (SPPN_10495) - 1985621..1986658 (-) 1038 Protein_2082 zinc-dependent alcohol dehydrogenase family protein -
  SPPN_RS10375 (SPPN_10500) - 1986977..1987216 (-) 240 WP_000907298.1 hypothetical protein -
  SPPN_RS10380 (SPPN_10505) - 1987330..1987764 (-) 435 WP_000355912.1 cytidine deaminase family protein -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38566.56 Da        Isoelectric Point: 9.4870

>NTDB_id=42036 SPPN_RS10355 WP_080564700.1 1983124..1984140(-) (comGB/cglB) [Streptococcus pseudopneumoniae IS7493]
MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLDRSALLDRQCVTQMRVGLSQGKSFSEMMESLGCSSAI
VTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF
LGMIVFVSVGVLLALTFYKRSSKMRVFSILARLPFIGIFVQTYLTAYYAREWGNMISQGMELTQIFQMMQEQGSQFFKEI
GQDLAHSLQNGREFSQTIGTYPFFKKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=42036 SPPN_RS10355 WP_080564700.1 1983124..1984140(-) (comGB/cglB) [Streptococcus pseudopneumoniae IS7493]
ATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAAGCAAAAAAATATCATCACCCTATTTAA
CAATCTCTTTTCTAGCGGTTTTCATCTGGTGGAGACCATCTCCTTTTTAGATAGGAGTGCTTTGTTGGACAGGCAGTGTG
TGACCCAGATGCGTGTGGGCTTGTCTCAGGGGAAATCATTCTCAGAAATGATGGAAAGTTTGGGATGTTCAAGTGCCATT
GTCACCCAGTTATCCCTAGCTGAAGTTCATGGCAATCTCCACCTGAGTTTGGGAAAGATAGAAGAATATCTGGACAATCT
GGCTAAGGTCAAGAAAAAATTGATTGAAGTAGCGACCTATCCCTTGATTTTGCTGGGTTTTCTTCTCTTAATTATGCTGG
GGTTACGGAATTACCTGCTCCCACAACTGGATAGTAGCAATATTGCCACCCAAATTATCGGTAATCTGCCACAAATCTTT
CTAGGAATGATAGTTTTTGTTTCAGTAGGTGTCCTTTTAGCACTCACTTTTTATAAAAGAAGTTCTAAGATGCGCGTCTT
TTCTATCTTAGCGCGCCTTCCCTTTATTGGAATCTTTGTGCAGACCTATTTGACAGCCTATTATGCACGTGAATGGGGGA
ATATGATTTCACAGGGAATGGAGTTGACGCAGATTTTTCAAATGATGCAGGAACAAGGTTCCCAGTTCTTTAAAGAAATC
GGTCAAGATTTGGCTCATTCTCTCCAAAATGGTCGAGAATTTTCTCAAACTATAGGAACCTATCCTTTCTTTAAAAAGGA
GTTGAGTCTCATCATCGAGTATGGTGAAGTCAAGTCTAAGCTGGGGAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACCATGAATTTGGTGCAGCCACTGGTTTTTATCTTTGTAGCACTGATTATCGTT
TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus pneumoniae TIGR4

96.154

100

0.962
  comGB/cglB Streptococcus pneumoniae Rx1

96.154

100

0.962
  comGB/cglB Streptococcus pneumoniae D39

96.154

100

0.962
  comGB/cglB Streptococcus pneumoniae R6

96.154

100

0.962
  comGB/cglB Streptococcus mitis NCTC 12261

95.858

100

0.959
  comGB/cglB Streptococcus mitis SK321

94.675

100

0.947
  comYB Streptococcus gordonii str. Challis substr. CH1

70.536

99.408

0.701
  comYB Streptococcus mutans UA140

57.994

94.379

0.547
  comYB Streptococcus mutans UA159

57.994

94.379

0.547
  comGB Lactococcus lactis subsp. cremoris KW2

49.701

98.817

0.491

Multiple sequence alignment