Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC/cglC   Type   Machinery gene
Locus tag   M594_RS00900 Genome accession   NZ_CP047883
Coordinates   181330..181653 (+) Length   107 a.a.
NCBI ID   WP_000738641.1    Uniprot ID   -
Organism   Streptococcus mitis strain S022-V3-A4     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 176330..186653
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M594_RS00880 (M594_00900) nagA 177639..178790 (+) 1152 WP_033687416.1 N-acetylglucosamine-6-phosphate deacetylase -
  M594_RS00885 (M594_00905) - 178982..179347 (+) 366 WP_173875725.1 DUF1033 family protein -
  M594_RS00890 (M594_00910) comGA/cglA/cilD 179423..180364 (+) 942 WP_173875726.1 competence type IV pilus ATPase ComGA Machinery gene
  M594_RS00895 (M594_00915) comGB/cglB 180312..181328 (+) 1017 WP_153209728.1 competence type IV pilus assembly protein ComGB Machinery gene
  M594_RS00900 (M594_00920) comGC/cglC 181330..181653 (+) 324 WP_000738641.1 comG operon protein ComGC Machinery gene
  M594_RS00905 (M594_00925) comGD/cglD 181616..181996 (+) 381 WP_173875727.1 competence type IV pilus minor pilin ComGD Machinery gene
  M594_RS00910 (M594_00930) comGE/cglE 182013..182315 (+) 303 WP_153209718.1 competence type IV pilus minor pilin ComGE Machinery gene
  M594_RS00915 (M594_00935) comGF/cglF 182278..182739 (+) 462 WP_173875728.1 competence type IV pilus minor pilin ComGF Machinery gene
  M594_RS00920 (M594_00940) comGG/cglG 182717..183130 (+) 414 WP_173875729.1 competence type IV pilus minor pilin ComGG Machinery gene
  M594_RS00925 (M594_00945) - 183163..183750 (+) 588 WP_173875730.1 class I SAM-dependent methyltransferase -
  M594_RS00930 (M594_00950) comYH 183811..184764 (+) 954 WP_173875731.1 class I SAM-dependent methyltransferase Machinery gene
  M594_RS00935 (M594_00955) - 184814..186004 (+) 1191 WP_084886490.1 acetate kinase -
  M594_RS00940 (M594_00960) rnpA 186154..186525 (+) 372 WP_000739245.1 ribonuclease P protein component -

Sequence


Protein


Download         Length: 107 a.a.        Molecular weight: 11958.09 Da        Isoelectric Point: 9.9097

>NTDB_id=418226 M594_RS00900 WP_000738641.1 181330..181653(+) (comGC/cglC) [Streptococcus mitis strain S022-V3-A4]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLLLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLDKNEDASLSKLQA
DGRITEEQAKAYKEYHAKQNTSQTVAD

Nucleotide


Download         Length: 324 bp        

>NTDB_id=418226 M594_RS00900 WP_000738641.1 181330..181653(+) (comGC/cglC) [Streptococcus mitis strain S022-V3-A4]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCGAAAGTGAAGGCTTTTACACTTGTGGAGATGTTGGTGGTCTTGCTCAT
CATCAGCGTGCTTCTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAACGACAAAGGAAAAGCTGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAGCTTTATAGCTTAGATAAAAATGAAGATGCTAGCCTAAGCAAGTTACAAGCA
GATGGGAGAATCACAGAAGAACAGGCTAAAGCTTATAAAGAATACCATGCTAAACAAAATACCAGTCAAACCGTTGCAGA
TTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis NCTC 12261

100

100

1

  comGC/cglC Streptococcus mitis SK321

93.204

96.262

0.897

  comGC/cglC Streptococcus pneumoniae Rx1

92.157

95.327

0.879

  comGC/cglC Streptococcus pneumoniae D39

92.157

95.327

0.879

  comGC/cglC Streptococcus pneumoniae R6

92.157

95.327

0.879

  comGC/cglC Streptococcus pneumoniae TIGR4

90.291

96.262

0.869

  comYC Streptococcus gordonii str. Challis substr. CH1

69.524

98.131

0.682

  comYC Streptococcus mutans UA140

68.421

88.785

0.607

  comYC Streptococcus mutans UA159

68.421

88.785

0.607

  comYC Streptococcus suis isolate S10

70.37

75.701

0.533

  comGC Lactococcus lactis subsp. cremoris KW2

54.455

94.393

0.514

  comGC Staphylococcus aureus MW2

51.163

80.374

0.411

  comGC Staphylococcus aureus N315

51.163

80.374

0.411


Multiple sequence alignment