Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGD/cglD   Type   Machinery gene
Locus tag   M594_RS00905 Genome accession   NZ_CP047883
Coordinates   181616..181996 (+) Length   126 a.a.
NCBI ID   WP_173875727.1    Uniprot ID   -
Organism   Streptococcus mitis strain S022-V3-A4     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 176616..186996
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M594_RS00880 (M594_00900) nagA 177639..178790 (+) 1152 WP_033687416.1 N-acetylglucosamine-6-phosphate deacetylase -
  M594_RS00885 (M594_00905) - 178982..179347 (+) 366 WP_173875725.1 DUF1033 family protein -
  M594_RS00890 (M594_00910) comGA/cglA/cilD 179423..180364 (+) 942 WP_173875726.1 competence type IV pilus ATPase ComGA Machinery gene
  M594_RS00895 (M594_00915) comGB/cglB 180312..181328 (+) 1017 WP_153209728.1 competence type IV pilus assembly protein ComGB Machinery gene
  M594_RS00900 (M594_00920) comGC/cglC 181330..181653 (+) 324 WP_000738641.1 comG operon protein ComGC Machinery gene
  M594_RS00905 (M594_00925) comGD/cglD 181616..181996 (+) 381 WP_173875727.1 competence type IV pilus minor pilin ComGD Machinery gene
  M594_RS00910 (M594_00930) comGE/cglE 182013..182315 (+) 303 WP_153209718.1 competence type IV pilus minor pilin ComGE Machinery gene
  M594_RS00915 (M594_00935) comGF/cglF 182278..182739 (+) 462 WP_173875728.1 competence type IV pilus minor pilin ComGF Machinery gene
  M594_RS00920 (M594_00940) comGG/cglG 182717..183130 (+) 414 WP_173875729.1 competence type IV pilus minor pilin ComGG Machinery gene
  M594_RS00925 (M594_00945) - 183163..183750 (+) 588 WP_173875730.1 class I SAM-dependent methyltransferase -
  M594_RS00930 (M594_00950) comYH 183811..184764 (+) 954 WP_173875731.1 class I SAM-dependent methyltransferase Machinery gene
  M594_RS00935 (M594_00955) - 184814..186004 (+) 1191 WP_084886490.1 acetate kinase -
  M594_RS00940 (M594_00960) rnpA 186154..186525 (+) 372 WP_000739245.1 ribonuclease P protein component -

Sequence


Protein


Download         Length: 126 a.a.        Molecular weight: 13630.72 Da        Isoelectric Point: 10.0971

>NTDB_id=418227 M594_RS00905 WP_173875727.1 181616..181996(+) (comGD/cglD) [Streptococcus mitis strain S022-V3-A4]
MLNKIPVKPLQIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEDQIFFMEFEELYRETQKRSVASQQKTSLNLDGQT
ITNGSQKLTVPKGIQAPSGQSITFDRAGGNSSLAKVEFHTSKGAIR

Nucleotide


Download         Length: 381 bp        

>NTDB_id=418227 M594_RS00905 WP_173875727.1 181616..181996(+) (comGD/cglD) [Streptococcus mitis strain S022-V3-A4]
ATGCTAAACAAAATACCAGTCAAACCGTTGCAGATTAAGGCCTTTACCATGCTTGAAAGTCTCTTGGTTTTGGGTCTTGT
GAGTATCCTTGCCTTGGGCTTGTCAGGTTCTGTTCAGTCCACTTTTGCGGCGGTAGAGGATCAGATTTTCTTTATGGAGT
TTGAAGAACTCTATCGGGAAACCCAAAAACGCAGTGTAGCCAGTCAGCAAAAGACTAGTCTGAACTTAGATGGGCAGACA
ATCACTAACGGCAGTCAAAAGTTGACAGTTCCCAAAGGGATTCAGGCACCATCAGGCCAAAGTATTACATTTGATCGAGC
TGGGGGCAATTCGTCCCTGGCTAAGGTTGAATTTCATACCAGTAAAGGAGCGATTCGTTAG

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGD/cglD Streptococcus mitis NCTC 12261

96.825

100

0.968

  comGD/cglD Streptococcus pneumoniae Rx1

95.652

91.27

0.873

  comGD/cglD Streptococcus pneumoniae D39

95.652

91.27

0.873

  comGD/cglD Streptococcus pneumoniae R6

95.652

91.27

0.873

  comGD/cglD Streptococcus mitis SK321

94.783

91.27

0.865

  comGD/cglD Streptococcus pneumoniae TIGR4

94.783

91.27

0.865

  comYD Streptococcus gordonii str. Challis substr. CH1

53.719

96.032

0.516

  comYD Streptococcus mutans UA140

48.649

88.095

0.429

  comYD Streptococcus mutans UA159

48.649

88.095

0.429


Multiple sequence alignment