Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   M594_RS00930 Genome accession   NZ_CP047883
Coordinates   183811..184764 (+) Length   317 a.a.
NCBI ID   WP_173875731.1    Uniprot ID   A0A6M9F7Z9
Organism   Streptococcus mitis strain S022-V3-A4     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 178811..189764
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M594_RS00885 (M594_00905) - 178982..179347 (+) 366 WP_173875725.1 DUF1033 family protein -
  M594_RS00890 (M594_00910) comGA/cglA/cilD 179423..180364 (+) 942 WP_173875726.1 competence type IV pilus ATPase ComGA Machinery gene
  M594_RS00895 (M594_00915) comGB/cglB 180312..181328 (+) 1017 WP_153209728.1 competence type IV pilus assembly protein ComGB Machinery gene
  M594_RS00900 (M594_00920) comGC/cglC 181330..181653 (+) 324 WP_000738641.1 comG operon protein ComGC Machinery gene
  M594_RS00905 (M594_00925) comGD/cglD 181616..181996 (+) 381 WP_173875727.1 competence type IV pilus minor pilin ComGD Machinery gene
  M594_RS00910 (M594_00930) comGE/cglE 182013..182315 (+) 303 WP_153209718.1 competence type IV pilus minor pilin ComGE Machinery gene
  M594_RS00915 (M594_00935) comGF/cglF 182278..182739 (+) 462 WP_173875728.1 competence type IV pilus minor pilin ComGF Machinery gene
  M594_RS00920 (M594_00940) comGG/cglG 182717..183130 (+) 414 WP_173875729.1 competence type IV pilus minor pilin ComGG Machinery gene
  M594_RS00925 (M594_00945) - 183163..183750 (+) 588 WP_173875730.1 class I SAM-dependent methyltransferase -
  M594_RS00930 (M594_00950) comYH 183811..184764 (+) 954 WP_173875731.1 class I SAM-dependent methyltransferase Machinery gene
  M594_RS00935 (M594_00955) - 184814..186004 (+) 1191 WP_084886490.1 acetate kinase -
  M594_RS00940 (M594_00960) rnpA 186154..186525 (+) 372 WP_000739245.1 ribonuclease P protein component -
  M594_RS00945 (M594_00965) - 186500..187324 (+) 825 WP_217423022.1 membrane protein insertase YidC -
  M594_RS00950 (M594_00970) jag 187342..188331 (+) 990 WP_173875732.1 RNA-binding cell elongation regulator Jag/EloR -
  M594_RS00955 (M594_00975) - 188382..189005 (+) 624 WP_173875733.1 ribonuclease P -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35592.74 Da        Isoelectric Point: 4.3070

>NTDB_id=418231 M594_RS00930 WP_173875731.1 183811..184764(+) (comYH) [Streptococcus mitis strain S022-V3-A4]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELEQVKENNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEKEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKGWLKEEASLTAMISLPENLFASAKQSKTIFILQKKSETAVDPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=418231 M594_RS00930 WP_173875731.1 183811..184764(+) (comYH) [Streptococcus mitis strain S022-V3-A4]
ATGGATTTTGAAAAAATTGAACAAGCTTATACGTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCCTGGTGGAGCAAAACAGCATCTATTTGGATGGTGAGACTGAGTTAGAGCAGGTCAAGGAAAACAATC
AGGCCCTTAAACGCTTAGCGCTTCGCAAAGAAGAATGGCTCAAAACCTACCAGTTTCTCTTGATGAAGGCTGGGCAGACA
GAGCCCCTACAGGCCAATCACCAGTTTACACCAGATGCCATTGCTTTACTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGAAGGAGATTACGATCCTCGAAATGGGTTCTGGGATGGGAATTTTGGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAGTGGATGATTTGCTGATTGATTTGGCGGCTAGTATGGCAGATGTAATTGGTTTGCAG
GCTGGTTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGCGACTTGCCTGTCGG
CTATTATCCTGATGACGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGTCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGACTTAAGTATCTCAAGTCAGACGGATATGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGACTTGTTGAAAGGTTGGTTGAAAGAGGAGGCAAGTCTGACTGCCATGATTAGTTTGCCTGAAAATCTCTTTGCCAG
TGCTAAACAATCCAAGACGATTTTTATCTTACAGAAGAAAAGTGAAACAGCAGTAGATCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-284)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6M9F7Z9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.952

98.738

0.543
  comYH Streptococcus mutans UA159

54.633

98.738

0.539

Multiple sequence alignment