Detailed information
Bioinformatically predicted
Overview
| Name | comX/comX2 | Type | Regulator |
| Locus tag | GL188_RS00080 | Genome accession | NZ_CP046359 |
| Coordinates | 16713..17192 (+) | Length | 159 a.a. |
| NCBI ID | WP_000588925.1 | Uniprot ID | A0AAX3HEV8 |
| Organism | Streptococcus pneumoniae strain 573 | ||
| Function | activate transcription of late competence genes (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 14633..46652 | 16713..17192 | within | 0 |
Gene organization within MGE regions
Location: 14633..46652
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GL188_RS00075 (GL188_00075) | ftsH | 14633..16591 (+) | 1959 | WP_000744557.1 | ATP-dependent zinc metalloprotease FtsH | - |
| GL188_RS00080 (GL188_00080) | comX/comX2 | 16713..17192 (+) | 480 | WP_000588925.1 | sigma-70 family RNA polymerase sigma factor | Regulator |
| GL188_RS00115 (GL188_00115) | - | 22683..23529 (+) | 847 | Protein_17 | IS630 family transposase | - |
| GL188_RS00120 (GL188_00120) | - | 23564..24361 (-) | 798 | Protein_18 | transposase | - |
| GL188_RS00125 (GL188_00125) | comW | 24627..24863 (+) | 237 | WP_000939544.1 | sigma(X)-activator ComW | Regulator |
| GL188_RS00130 (GL188_00130) | - | 25094..26380 (+) | 1287 | WP_000205044.1 | adenylosuccinate synthase | - |
| GL188_RS00135 (GL188_00135) | tadA | 26581..27048 (+) | 468 | WP_000291870.1 | tRNA adenosine(34) deaminase TadA | - |
| GL188_RS10815 (GL188_00145) | - | 27257..27955 (-) | 699 | WP_001106362.1 | tyrosine-type recombinase/integrase | - |
| GL188_RS10820 (GL188_00150) | - | 28045..28392 (-) | 348 | WP_001839379.1 | hypothetical protein | - |
| GL188_RS00150 (GL188_00155) | - | 28453..29523 (-) | 1071 | WP_000401841.1 | type I restriction endonuclease | - |
| GL188_RS00155 (GL188_00160) | - | 29540..29920 (-) | 381 | WP_000170931.1 | ImmA/IrrE family metallo-endopeptidase | - |
| GL188_RS00160 (GL188_00165) | - | 29933..30196 (-) | 264 | WP_000285962.1 | type II toxin-antitoxin system RelE family toxin | - |
| GL188_RS00165 (GL188_00170) | - | 30196..30429 (-) | 234 | WP_000156419.1 | hypothetical protein | - |
| GL188_RS00170 (GL188_00175) | - | 30429..30797 (-) | 369 | WP_000464160.1 | helix-turn-helix domain-containing protein | - |
| GL188_RS00175 (GL188_00180) | - | 31369..31560 (+) | 192 | WP_001112859.1 | DNA-binding protein | - |
| GL188_RS00180 (GL188_00185) | - | 31583..31786 (+) | 204 | WP_001247549.1 | hypothetical protein | - |
| GL188_RS00185 (GL188_00190) | - | 31941..32108 (-) | 168 | WP_000024181.1 | YjzC family protein | - |
| GL188_RS00190 (GL188_00195) | - | 32113..32493 (+) | 381 | Protein_32 | autolysin | - |
| GL188_RS00195 (GL188_00200) | - | 32713..32892 (-) | 180 | WP_001209433.1 | hypothetical protein | - |
| GL188_RS00200 | - | 33034..33183 (-) | 150 | WP_001030863.1 | hypothetical protein | - |
| GL188_RS00205 (GL188_00205) | - | 33488..33931 (+) | 444 | WP_000701992.1 | dUTP diphosphatase | - |
| GL188_RS00210 (GL188_00210) | - | 33933..34448 (+) | 516 | WP_000691236.1 | histidine phosphatase family protein | - |
| GL188_RS00215 (GL188_00215) | radA | 34462..35823 (+) | 1362 | WP_075213698.1 | DNA repair protein RadA | Machinery gene |
| GL188_RS00220 (GL188_00220) | - | 35896..36393 (+) | 498 | WP_001809263.1 | beta-class carbonic anhydrase | - |
| GL188_RS00225 (GL188_00225) | - | 36418..37201 (+) | 784 | Protein_39 | PrsW family glutamic-type intramembrane protease | - |
| GL188_RS00230 (GL188_00230) | - | 37346..38314 (+) | 969 | WP_000010157.1 | ribose-phosphate diphosphokinase | - |
| GL188_RS00235 (GL188_00235) | - | 38448..38729 (-) | 282 | Protein_41 | transposase family protein | - |
| GL188_RS10795 | - | 38856..39738 (-) | 883 | Protein_42 | Rpn family recombination-promoting nuclease/putative transposase | - |
| GL188_RS00255 (GL188_00255) | polA | 39994..42627 (+) | 2634 | WP_024477951.1 | DNA polymerase I | - |
| GL188_RS00260 (GL188_00260) | - | 42712..43149 (+) | 438 | WP_000076479.1 | CoA-binding protein | - |
| GL188_RS10825 | - | 43190..43528 (+) | 339 | WP_226956234.1 | hypothetical protein | - |
| GL188_RS00270 (GL188_00270) | - | 43557..44567 (-) | 1011 | WP_000009170.1 | YeiH family protein | - |
| GL188_RS00275 (GL188_00275) | - | 44716..45885 (+) | 1170 | WP_000366342.1 | pyridoxal phosphate-dependent aminotransferase | - |
| GL188_RS00280 (GL188_00280) | recO | 45882..46652 (+) | 771 | WP_000616164.1 | DNA repair protein RecO | - |
Sequence
Protein
Download Length: 159 a.a. Molecular weight: 19887.54 Da Isoelectric Point: 7.3798
>NTDB_id=403306 GL188_RS00080 WP_000588925.1 16713..17192(+) (comX/comX2) [Streptococcus pneumoniae strain 573]
MIKELYEEVQGTVYKCRNEYYLHLWELSDWEQEGMLCLHELISREEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRR
YDKEPYEEVGEISHRISEGGLWLDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH
MIKELYEEVQGTVYKCRNEYYLHLWELSDWEQEGMLCLHELISREEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRR
YDKEPYEEVGEISHRISEGGLWLDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH
Nucleotide
Download Length: 480 bp
>NTDB_id=403306 GL188_RS00080 WP_000588925.1 16713..17192(+) (comX/comX2) [Streptococcus pneumoniae strain 573]
ATGATTAAAGAATTGTATGAAGAAGTCCAAGGGACTGTGTATAAGTGTAGAAATGAATATTACCTTCATTTATGGGAATT
GTCGGATTGGGAGCAAGAAGGCATGCTCTGCTTACATGAATTGATTAGTAGAGAAGAAGGACTGGTAGACGATATTCCAC
GTTTAAGGAAATATTTCAAGACCAAGTTTCGAAATCGAATTTTAGACTATATCCGTAAACAGGAAAGTCAGAAGCGTAGA
TACGATAAAGAACCCTATGAAGAAGTGGGTGAGATCAGTCATCGTATAAGTGAGGGGGGTCTCTGGCTAGATGATTATTA
TCTCTTTCATGAAACACTAAGAGATTATAGAAACAAACAAAGTAAAGAGAAACAAGAAGAACTAGAACGCGTCTTAAGCA
ATGAACGATTTCGAGGGCGTCAAAGAGTATTAAGAGACTTACGCATTGTGTTTAAGGAGTTTACTATCCGTACCCATTAG
ATGATTAAAGAATTGTATGAAGAAGTCCAAGGGACTGTGTATAAGTGTAGAAATGAATATTACCTTCATTTATGGGAATT
GTCGGATTGGGAGCAAGAAGGCATGCTCTGCTTACATGAATTGATTAGTAGAGAAGAAGGACTGGTAGACGATATTCCAC
GTTTAAGGAAATATTTCAAGACCAAGTTTCGAAATCGAATTTTAGACTATATCCGTAAACAGGAAAGTCAGAAGCGTAGA
TACGATAAAGAACCCTATGAAGAAGTGGGTGAGATCAGTCATCGTATAAGTGAGGGGGGTCTCTGGCTAGATGATTATTA
TCTCTTTCATGAAACACTAAGAGATTATAGAAACAAACAAAGTAAAGAGAAACAAGAAGAACTAGAACGCGTCTTAAGCA
ATGAACGATTTCGAGGGCGTCAAAGAGTATTAAGAGACTTACGCATTGTGTTTAAGGAGTTTACTATCCGTACCCATTAG
Domains
No domain identified.
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.