Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   GLO74_RS01020 Genome accession   NZ_CP046354
Coordinates   204183..204509 (+) Length   108 a.a.
NCBI ID   WP_000738625.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 310     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 199183..209509
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GLO74_RS00995 (GLO74_01015) nagA 199313..200464 (+) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -
  GLO74_RS01000 (GLO74_01020) - 200627..201685 (+) 1059 WP_000649471.1 zinc-dependent alcohol dehydrogenase family protein -
  GLO74_RS01005 (GLO74_01025) - 201836..202201 (+) 366 WP_000286415.1 DUF1033 family protein -
  GLO74_RS01010 (GLO74_01030) comGA/cglA/cilD 202276..203217 (+) 942 WP_000249555.1 competence type IV pilus ATPase ComGA Machinery gene
  GLO74_RS01015 (GLO74_01035) comGB/cglB 203165..204181 (+) 1017 WP_074017570.1 competence type IV pilus assembly protein ComGB Machinery gene
  GLO74_RS01020 (GLO74_01040) comGC/cglC 204183..204509 (+) 327 WP_000738625.1 competence type IV pilus major pilin ComGC Machinery gene
  GLO74_RS01025 (GLO74_01045) comGD/cglD 204502..204906 (+) 405 WP_000588030.1 competence type IV pilus minor pilin ComGD Machinery gene
  GLO74_RS01030 (GLO74_01050) comGE/cglE 204869..205171 (+) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  GLO74_RS01035 (GLO74_01055) comGF/cglF 205134..205595 (+) 462 WP_000250539.1 competence type IV pilus minor pilin ComGF Machinery gene
  GLO74_RS01040 (GLO74_01060) comGG/cglG 205573..205965 (+) 393 WP_001818028.1 competence type IV pilus minor pilin ComGG Machinery gene
  GLO74_RS01045 (GLO74_01065) - 206121..206708 (+) 588 WP_000679779.1 class I SAM-dependent methyltransferase -
  GLO74_RS01050 (GLO74_01075) comYH 206769..207722 (+) 954 WP_000345122.1 class I SAM-dependent methyltransferase Machinery gene
  GLO74_RS01055 (GLO74_01080) - 207773..208963 (+) 1191 WP_000167765.1 acetate kinase -
  GLO74_RS11245 - 208964..209095 (+) 132 WP_000768904.1 hypothetical protein -
  GLO74_RS01060 (GLO74_01085) rnpA 209112..209483 (+) 372 WP_000739247.1 ribonuclease P protein component -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12143.28 Da        Isoelectric Point: 10.0055

>NTDB_id=402930 GLO74_RS01020 WP_000738625.1 204183..204509(+) (comGC/cglC) [Streptococcus pneumoniae strain 310]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLDKNEDATLSKLQG
DGRITEEQVKAYNEYYTKNGGANRKVND

Nucleotide


Download         Length: 327 bp        

>NTDB_id=402930 GLO74_RS01020 WP_000738625.1 204183..204509(+) (comGC/cglC) [Streptococcus pneumoniae strain 310]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAGATGTTAGTAGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGATAAAAATGAAGATGCTACTCTGAGCAAGTTACAAGGA
GATGGGCGCATCACGGAAGAACAGGTTAAAGCTTATAATGAATACTATACTAAAAATGGAGGGGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis SK321

95.37

100

0.954
  comGC/cglC Streptococcus pneumoniae Rx1

92.593

100

0.926
  comGC/cglC Streptococcus pneumoniae D39

92.593

100

0.926
  comGC/cglC Streptococcus pneumoniae R6

92.593

100

0.926
  comGC/cglC Streptococcus pneumoniae TIGR4

92.593

100

0.926
  comGC/cglC Streptococcus mitis NCTC 12261

92.857

90.741

0.843
  comYC Streptococcus gordonii str. Challis substr. CH1

67.961

95.37

0.648
  comYC Streptococcus mutans UA140

62.745

94.444

0.593
  comYC Streptococcus mutans UA159

62.745

94.444

0.593
  comGC Lactococcus lactis subsp. cremoris KW2

56.863

94.444

0.537
  comYC Streptococcus suis isolate S10

64.773

81.481

0.528
  comGC Staphylococcus aureus MW2

47.674

79.63

0.38
  comGC Staphylococcus aureus N315

47.674

79.63

0.38

Multiple sequence alignment