Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   GLO74_RS01050 Genome accession   NZ_CP046354
Coordinates   206769..207722 (+) Length   317 a.a.
NCBI ID   WP_000345122.1    Uniprot ID   A0A0I7TJC1
Organism   Streptococcus pneumoniae strain 310     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 201769..212722
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GLO74_RS01005 (GLO74_01025) - 201836..202201 (+) 366 WP_000286415.1 DUF1033 family protein -
  GLO74_RS01010 (GLO74_01030) comGA/cglA/cilD 202276..203217 (+) 942 WP_000249555.1 competence type IV pilus ATPase ComGA Machinery gene
  GLO74_RS01015 (GLO74_01035) comGB/cglB 203165..204181 (+) 1017 WP_074017570.1 competence type IV pilus assembly protein ComGB Machinery gene
  GLO74_RS01020 (GLO74_01040) comGC/cglC 204183..204509 (+) 327 WP_000738625.1 competence type IV pilus major pilin ComGC Machinery gene
  GLO74_RS01025 (GLO74_01045) comGD/cglD 204502..204906 (+) 405 WP_000588030.1 competence type IV pilus minor pilin ComGD Machinery gene
  GLO74_RS01030 (GLO74_01050) comGE/cglE 204869..205171 (+) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  GLO74_RS01035 (GLO74_01055) comGF/cglF 205134..205595 (+) 462 WP_000250539.1 competence type IV pilus minor pilin ComGF Machinery gene
  GLO74_RS01040 (GLO74_01060) comGG/cglG 205573..205965 (+) 393 WP_001818028.1 competence type IV pilus minor pilin ComGG Machinery gene
  GLO74_RS01045 (GLO74_01065) - 206121..206708 (+) 588 WP_000679779.1 class I SAM-dependent methyltransferase -
  GLO74_RS01050 (GLO74_01075) comYH 206769..207722 (+) 954 WP_000345122.1 class I SAM-dependent methyltransferase Machinery gene
  GLO74_RS01055 (GLO74_01080) - 207773..208963 (+) 1191 WP_000167765.1 acetate kinase -
  GLO74_RS11245 - 208964..209095 (+) 132 WP_000768904.1 hypothetical protein -
  GLO74_RS01060 (GLO74_01085) rnpA 209112..209483 (+) 372 WP_000739247.1 ribonuclease P protein component -
  GLO74_RS01065 (GLO74_01090) - 209458..210282 (+) 825 WP_000727904.1 membrane protein insertase YidC -
  GLO74_RS01070 (GLO74_01095) jag 210301..211287 (+) 987 WP_000260025.1 RNA-binding cell elongation regulator Jag/EloR -
  GLO74_RS01075 (GLO74_01100) - 211338..211961 (+) 624 WP_000932659.1 hypothetical protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35745.94 Da        Isoelectric Point: 4.2706

>NTDB_id=402935 GLO74_RS01050 WP_000345122.1 206769..207722(+) (comYH) [Streptococcus pneumoniae strain 310]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEMDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSNLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFILQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=402935 GLO74_RS01050 WP_000345122.1 206769..207722(+) (comYH) [Streptococcus pneumoniae strain 310]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTTATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCAGATGCCATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAATGGATGATTTGCTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTTGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTAATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTCTGCCTGAAAATCTCTTTGCTAA
TGCCAAACAATCTAAGACTATTTTTATCTTACAGAAGAAAAATGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0I7TJC1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

53.994

98.738

0.533
  comYH Streptococcus mutans UA159

53.674

98.738

0.53

Multiple sequence alignment