Detailed information NTG0402933

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: GLO74_RS01035
• Genome accession: NZ_CP046354
• Coordinates: 205134..205595 (+)
• Length: 153 a.a.
• NCBI ID: WP_000250539.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 310
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 200134..210595

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GLO74_RS01000 (GLO74_01020)	-	200627..201685 (+)	1059	WP_000649471.1	zinc-dependent alcohol dehydrogenase family protein	-
GLO74_RS01005 (GLO74_01025)	-	201836..202201 (+)	366	WP_000286415.1	DUF1033 family protein	-
GLO74_RS01010 (GLO74_01030)	comGA/cglA/cilD	202276..203217 (+)	942	WP_000249555.1	competence type IV pilus ATPase ComGA	Machinery gene
GLO74_RS01015 (GLO74_01035)	comGB/cglB	203165..204181 (+)	1017	WP_074017570.1	competence type IV pilus assembly protein ComGB	Machinery gene
GLO74_RS01020 (GLO74_01040)	comGC/cglC	204183..204509 (+)	327	WP_000738625.1	competence type IV pilus major pilin ComGC	Machinery gene
GLO74_RS01025 (GLO74_01045)	comGD/cglD	204502..204906 (+)	405	WP_000588030.1	competence type IV pilus minor pilin ComGD	Machinery gene
GLO74_RS01030 (GLO74_01050)	comGE/cglE	204869..205171 (+)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
GLO74_RS01035 (GLO74_01055)	comGF/cglF	205134..205595 (+)	462	WP_000250539.1	competence type IV pilus minor pilin ComGF	Machinery gene
GLO74_RS01040 (GLO74_01060)	comGG/cglG	205573..205965 (+)	393	WP_001818028.1	competence type IV pilus minor pilin ComGG	Machinery gene
GLO74_RS01045 (GLO74_01065)	-	206121..206708 (+)	588	WP_000679779.1	class I SAM-dependent methyltransferase	-
GLO74_RS01050 (GLO74_01075)	comYH	206769..207722 (+)	954	WP_000345122.1	class I SAM-dependent methyltransferase	Machinery gene
GLO74_RS01055 (GLO74_01080)	-	207773..208963 (+)	1191	WP_000167765.1	acetate kinase	-
GLO74_RS11245	-	208964..209095 (+)	132	WP_000768904.1	hypothetical protein	-
GLO74_RS01060 (GLO74_01085)	rnpA	209112..209483 (+)	372	WP_000739247.1	ribonuclease P protein component	-
GLO74_RS01065 (GLO74_01090)	-	209458..210282 (+)	825	WP_000727904.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17851.34 Da
• Isoelectric Point: 6.4832

>NTDB_id=402933 GLO74_RS01035 WP_000250539.1 205134..205595(+) (comGF/cglF) [Streptococcus pneumoniae strain 310]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES

Nucleotide

• Length: 462 bp

>NTDB_id=402933 GLO74_RS01035 WP_000250539.1 205134..205595(+) (comGF/cglF) [Streptococcus pneumoniae strain 310]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAACTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae D39	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae R6	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae TIGR4	94.118	100	0.941
comGF/cglF	Streptococcus mitis SK321	92.81	100	0.928
comGF/cglF	Streptococcus mitis NCTC 12261	91.503	100	0.915