Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   G9P48_RS09290 Genome accession   NZ_CP050031
Coordinates   1941484..1942140 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain 33-6     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1936484..1947140
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  G9P48_RS09260 (G9P48_09255) dcyD 1937363..1938349 (+) 987 WP_001128205.1 D-cysteine desulfhydrase -
  G9P48_RS09265 (G9P48_09260) tcyL 1938364..1939032 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  G9P48_RS09270 (G9P48_09265) tcyN 1939029..1939781 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  G9P48_RS09275 (G9P48_09270) sdiA 1940011..1940733 (+) 723 WP_182116887.1 transcriptional regulator SdiA -
  G9P48_RS09280 (G9P48_09275) yecF 1940801..1941025 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  G9P48_RS09285 (G9P48_09280) yecU 1941012..1941188 (-) 177 WP_000590347.1 protein YecU -
  G9P48_RS23220 - 1941271..1941342 (-) 72 Protein_1836 transcriptional regulator -
  G9P48_RS09290 (G9P48_09285) letA 1941484..1942140 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  G9P48_RS09295 (G9P48_09290) uvrC 1942137..1943969 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  G9P48_RS09300 (G9P48_09295) pgsA 1944026..1944574 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  G9P48_RS09320 (G9P48_09315) yecA 1945224..1945889 (+) 666 WP_182116888.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=376093 G9P48_RS09290 WP_000611335.1 1941484..1942140(+) (letA) [Escherichia coli strain 33-6]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=376093 G9P48_RS09290 WP_000611335.1 1941484..1942140(+) (letA) [Escherichia coli strain 33-6]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486

Multiple sequence alignment