Detailed information NTG0352594

Bioinformatically predicted

Overview

• Name: comX/comX2
• Type: Regulator
• Locus tag: ES276_RS00070
• Genome accession: NZ_CP038252
• Coordinates: 15968..16441 (+)
• Length: 157 a.a.
• NCBI ID: WP_061633570.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901936
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	14440..15786	15968..16441	flank	182

Gene organization within MGE regions

Location: 14440..16441

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ES276_RS00065 (ES276_00065)	-	14440..15786 (+)	1347	WP_001808790.1	IS1380-like element ISSpn5 family transposase	-
ES276_RS00070 (ES276_00075)	comX/comX2	15968..16441 (+)	474	WP_061633570.1	hypothetical protein	Regulator

Sequence

Protein

• Length: 157 a.a.
• Molecular weight: 19655.22 Da
• Isoelectric Point: 6.9734

>NTDB_id=352594 ES276_RS00070 WP_061633570.1 15968..16441(+) (comX/comX2) [Streptococcus pneumoniae strain TVO_1901936]
MIWDEEVQGTVYKCRNEYYLHLWELSDWEQEGMLCLHELISREEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYD
KEPYEEVGEISHRISEGGLWLDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH

Nucleotide

• Length: 474 bp

>NTDB_id=352594 ES276_RS00070 WP_061633570.1 15968..16441(+) (comX/comX2) [Streptococcus pneumoniae strain TVO_1901936]
ATGATTTGGGATGAAGAAGTCCAAGGGACTGTGTATAAGTGTAGAAATGAATATTACCTTCATTTATGGGAATTGTCGGA
TTGGGAGCAAGAAGGCATGCTCTGCTTACATGAATTGATTAGTAGAGAAGAAGGACTGGTAGACGATATTCCACGTTTAA
GGAAATATTTCAAGACCAAGTTTCGAAATCGAATTTTAGACTATATCCGTAAACAGGAAAGTCAGAAGCGTAGATACGAT
AAAGAACCCTATGAAGAAGTGGGTGAGATCAGTCATCGTATAAGTGAGGGGGGTCTCTGGCTAGATGATTATTATCTCTT
TCATGAAACACTAAGAGATTATAGAAACAAACAAAGTAAAGAGAAACAAGAAGAACTAGAACGCGTCTTAAGCAATGAAC
GATTTCGAGGGCGTCAAAGAGTATTAAGAGACTTACGCATTGTGTTTAAGGAGTTTACTATCCGTACCCACTAG

Domains

No domain identified.

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX/comX2	Streptococcus pneumoniae TIGR4	100	97.452	0.975
comX/comX1	Streptococcus pneumoniae TIGR4	100	97.452	0.975
comX/comX2	Streptococcus pneumoniae Rx1	99.346	97.452	0.968
comX/comX1	Streptococcus pneumoniae Rx1	99.346	97.452	0.968
comX/comX2	Streptococcus pneumoniae D39	99.346	97.452	0.968
comX/comX1	Streptococcus pneumoniae D39	99.346	97.452	0.968
comX/comX2	Streptococcus pneumoniae R6	99.346	97.452	0.968
comX/comX1	Streptococcus pneumoniae R6	99.346	97.452	0.968
comX/sigX/comX1/sigX1	Streptococcus mitis NCTC 12261	92.157	97.452	0.898
comX/sigX/comX2/sigX2	Streptococcus mitis NCTC 12261	92.157	97.452	0.898
comX/sigX/comX2/sigX2	Streptococcus mitis SK321	90.789	96.815	0.879
comX/sigX/comX1/sigX1	Streptococcus mitis SK321	89.404	96.178	0.86
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	49.669	96.178	0.478
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	49.669	96.178	0.478
comX/sigX	Streptococcus suis D9	47.26	92.994	0.439
comX/sigX	Streptococcus suis isolate S10	47.26	92.994	0.439
comX/sigX	Streptococcus suis P1/7	47.26	92.994	0.439
comX/sigX	Streptococcus mutans UA159	47.26	92.994	0.439
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	40.268	94.904	0.382
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	40.268	94.904	0.382
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	40.268	94.904	0.382
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	40.268	94.904	0.382
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	40.268	94.904	0.382
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	40.268	94.904	0.382
comX	Streptococcus salivarius SK126	38.514	94.268	0.363
comX	Streptococcus thermophilus LMG 18311	38.514	94.268	0.363
comX	Streptococcus thermophilus LMD-9	38.514	94.268	0.363