Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   GFB63_RS05400 Genome accession   NZ_CP045596
Coordinates   1042562..1043923 (-) Length   453 a.a.
NCBI ID   WP_193838174.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain TK-P3A     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1037562..1048923
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GFB63_RS05380 (GFB63_05535) - 1039826..1040167 (+) 342 WP_024404826.1 LytTR family DNA-binding domain-containing protein -
  GFB63_RS05385 (GFB63_05540) comE/blpR 1040169..1040909 (+) 741 WP_193838172.1 response regulator transcription factor Regulator
  GFB63_RS05390 (GFB63_05545) - 1040920..1042260 (+) 1341 WP_193838173.1 sensor histidine kinase -
  GFB63_RS05395 (GFB63_05550) - 1042308..1042463 (-) 156 WP_096811960.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  GFB63_RS05400 (GFB63_05555) comB 1042562..1043923 (-) 1362 WP_193838174.1 bacteriocin secretion accessory protein Regulator
  GFB63_RS05405 (GFB63_05560) comA/nlmT 1043935..1046088 (-) 2154 WP_193838175.1 peptide cleavage/export ABC transporter Regulator
  GFB63_RS05410 (GFB63_05565) - 1046386..1046643 (+) 258 WP_039671027.1 Blp family class II bacteriocin -
  GFB63_RS05415 (GFB63_05570) - 1046660..1046854 (+) 195 WP_039671026.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  GFB63_RS05420 (GFB63_05575) - 1047456..1048806 (+) 1351 Protein_1026 IS3 family transposase -

Sequence

Protein


Download         Length: 453 a.a.        Molecular weight: 50315.50 Da        Isoelectric Point: 5.3052

>NTDB_id=345229 GFB63_RS05400 WP_193838174.1 1042562..1043923(-) (comB) [Streptococcus thermophilus strain TK-P3A]
MNPNLFKSAEFYQRRYHNFATLLIVPLILLVGFLLTFSLFAKKEITVTSRGEITPTTIIASIQSTSNNPITTNNLANNKL
VKKNELIIQYAETMESSQKQALETQLATLNRQKTGLETLKESLSQGTNLFTGEDEFGYINTFNNFITQSQDIELGISKTN
AEVSNQAALAGNTIAAIDTQINQIYHQIAEYEELRQAITNRQTSLSADNPHQATLNNFLAQSQQDSQTGLTDQYLSQINQ
SISGLESSIASLNIQRAGTGSVATYDNSFVTKVEVLRTQFLQSASQQLTTLETQITELVAQLEQASVRLENNTITAPETG
VIHLNSEFEGKSLIPSGSEIAQIYPNINQTKEFLITYYVTSEHVALLKEKQDVRLSLEKVGNQSITVVGKIKSIDKTATK
TEEGNLFKVTALAQLSDKHSDVIQYGLQGRVTSIIAKKTYFDYYKDKILSNHD

Nucleotide


Download         Length: 1362 bp        

>NTDB_id=345229 GFB63_RS05400 WP_193838174.1 1042562..1043923(-) (comB) [Streptococcus thermophilus strain TK-P3A]
ATGAACCCTAATTTGTTCAAAAGTGCTGAATTTTACCAGCGGCGCTACCATAATTTTGCGACACTCTTAATTGTCCCCTT
GATATTATTAGTCGGCTTTCTTCTAACCTTCTCCCTTTTTGCCAAAAAAGAGATTACCGTCACATCAAGAGGTGAAATTA
CTCCGACGACAATCATCGCTTCCATCCAATCCACCAGCAATAACCCTATCACAACCAATAATCTAGCCAATAACAAGCTG
GTTAAAAAGAATGAGCTCATCATCCAATACGCTGAAACTATGGAGAGTTCCCAAAAACAAGCCCTTGAAACCCAGCTAGC
CACTCTAAATAGACAGAAAACTGGACTTGAAACCCTCAAAGAAAGCCTGTCACAGGGAACGAACCTCTTTACAGGGGAGG
ACGAATTTGGCTATATCAATACTTTTAACAACTTTATCACCCAGTCACAGGACATCGAACTAGGAATTTCCAAAACCAAT
GCAGAGGTGAGTAACCAGGCCGCCCTAGCAGGTAATACCATTGCTGCGATTGACACGCAAATCAATCAAATCTATCACCA
AATAGCAGAATACGAGGAGCTTCGTCAAGCCATTACCAATAGACAGACCAGTTTATCAGCTGACAATCCACACCAAGCCA
CCTTAAACAATTTCTTAGCCCAATCCCAACAAGACTCCCAGACAGGATTAACTGATCAATACCTTTCTCAAATCAACCAA
AGTATCTCAGGGCTAGAATCATCCATAGCTAGTCTGAACATCCAACGAGCTGGAACTGGCTCTGTTGCAACCTATGATAA
CAGCTTTGTAACAAAGGTTGAGGTCCTAAGAACACAGTTTTTACAATCGGCCTCTCAGCAGCTGACCACCCTTGAAACGC
AAATCACAGAGCTAGTGGCACAGCTAGAGCAAGCATCCGTCCGACTAGAAAACAATACCATTACAGCTCCTGAAACAGGG
GTAATCCATCTCAATAGTGAGTTTGAAGGAAAGTCTTTGATTCCAAGCGGTAGTGAAATCGCTCAGATTTACCCCAATAT
CAATCAAACCAAAGAATTCCTCATTACTTACTACGTGACTTCAGAACATGTCGCCTTACTCAAAGAAAAACAAGACGTGC
GCCTGAGCTTAGAAAAAGTTGGCAACCAAAGCATCACTGTTGTTGGAAAAATTAAGTCTATCGATAAAACTGCTACTAAA
ACTGAGGAGGGGAATCTTTTCAAAGTTACTGCCTTGGCTCAACTATCCGACAAGCATAGCGACGTCATCCAGTACGGTCT
CCAGGGTCGAGTCACAAGTATCATTGCCAAGAAGACTTACTTTGATTACTACAAGGATAAAATTTTATCCAACCATGATT
AA

Domains

Predicted by InterProScan.

HlyD family secretion protein ()

(313-424)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae R6

38.444

99.338

0.382
  comB Streptococcus pneumoniae Rx1

38.444

99.338

0.382
  comB Streptococcus pneumoniae D39

38.444

99.338

0.382
  comB Streptococcus pneumoniae TIGR4

38.222

99.338

0.38
  comB Streptococcus mitis SK321

37.639

99.117

0.373
  comB Streptococcus mitis NCTC 12261

37.639

99.117

0.373
  comB Streptococcus gordonii str. Challis substr. CH1

36.444

99.338

0.362

Multiple sequence alignment