Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC/cglC   Type   Machinery gene
Locus tag   DV131_RS01970 Genome accession   NZ_CP031246
Coordinates   341758..342081 (-) Length   107 a.a.
NCBI ID   WP_000738628.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain M26368     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 336758..347081
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV131_RS01930 rnpA 336775..337146 (-) 372 WP_000739246.1 ribonuclease P protein component -
  DV131_RS12050 - 337163..337294 (-) 132 WP_000768904.1 hypothetical protein -
  DV131_RS01935 - 337295..338485 (-) 1191 WP_000167766.1 acetate kinase -
  DV131_RS01940 comYH 338536..339489 (-) 954 WP_000345133.1 class I SAM-dependent methyltransferase Machinery gene
  DV131_RS01945 - 339550..340144 (-) 595 Protein_342 methyltransferase domain-containing protein -
  DV131_RS01950 comGG/cglG 340281..340694 (-) 414 WP_000265615.1 competence type IV pilus minor pilin ComGG Machinery gene
  DV131_RS01955 comGF/cglF 340672..341133 (-) 462 WP_000250520.1 competence type IV pilus minor pilin ComGF Machinery gene
  DV131_RS01960 comGE/cglE 341096..341398 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  DV131_RS01965 comGD/cglD 341361..341795 (-) 435 WP_033606693.1 competence type IV pilus minor pilin ComGD Machinery gene
  DV131_RS01970 comGC/cglC 341758..342081 (-) 324 WP_000738628.1 comG operon protein ComGC Machinery gene
  DV131_RS01975 comGB/cglB 342083..343099 (-) 1017 WP_074017570.1 competence type IV pilus assembly protein ComGB Machinery gene
  DV131_RS01980 comGA/cglA/cilD 343047..343988 (-) 942 WP_000249555.1 competence type IV pilus ATPase ComGA Machinery gene
  DV131_RS01985 - 344063..344428 (-) 366 WP_000286415.1 DUF1033 family protein -
  DV131_RS01990 - 344579..345637 (-) 1059 WP_000649466.1 zinc-dependent alcohol dehydrogenase family protein -
  DV131_RS01995 nagA 345800..346951 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence


Protein


Download         Length: 107 a.a.        Molecular weight: 12232.41 Da        Isoelectric Point: 9.8887

>NTDB_id=304687 DV131_RS01970 WP_000738628.1 341758..342081(-) (comGC/cglC) [Streptococcus pneumoniae strain M26368]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQD
DGRITEEQAKAYKEYHDKQNTSQIVKD

Nucleotide


Download         Length: 324 bp        

>NTDB_id=304687 DV131_RS01970 WP_000738628.1 341758..342081(-) (comGC/cglC) [Streptococcus pneumoniae strain M26368]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAAATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTGGAAAAGAATGAAGATGCTAGCCTAAGAAAGTTACAAGAC
GATGGACGCATCACGGAAGAACAGGCTAAAGCCTATAAAGAATACCATGATAAACAAAATACTAGTCAAATCGTTAAAGA
TTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis NCTC 12261

93.458

100

0.935

  comGC/cglC Streptococcus pneumoniae D39

94.175

96.262

0.907

  comGC/cglC Streptococcus pneumoniae R6

94.175

96.262

0.907

  comGC/cglC Streptococcus pneumoniae Rx1

94.175

96.262

0.907

  comGC/cglC Streptococcus pneumoniae TIGR4

93.204

96.262

0.897

  comGC/cglC Streptococcus mitis SK321

88.35

96.262

0.85

  comYC Streptococcus gordonii str. Challis substr. CH1

69.388

91.589

0.636

  comYC Streptococcus mutans UA140

64.211

88.785

0.57

  comYC Streptococcus mutans UA159

64.211

88.785

0.57

  comYC Streptococcus suis isolate S10

69.136

75.701

0.523

  comGC Lactococcus lactis subsp. cremoris KW2

54.639

90.654

0.495

  comGC Staphylococcus aureus MW2

48.837

80.374

0.393

  comGC Staphylococcus aureus N315

48.837

80.374

0.393

  comGC Latilactobacillus sakei subsp. sakei 23K

45.349

80.374

0.364


Multiple sequence alignment