Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   DV131_RS01960 Genome accession   NZ_CP031246
Coordinates   341096..341398 (-) Length   100 a.a.
NCBI ID   WP_000413382.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain M26368     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 336096..346398
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV131_RS01930 rnpA 336775..337146 (-) 372 WP_000739246.1 ribonuclease P protein component -
  DV131_RS12050 - 337163..337294 (-) 132 WP_000768904.1 hypothetical protein -
  DV131_RS01935 - 337295..338485 (-) 1191 WP_000167766.1 acetate kinase -
  DV131_RS01940 comYH 338536..339489 (-) 954 WP_000345133.1 class I SAM-dependent methyltransferase Machinery gene
  DV131_RS01945 - 339550..340144 (-) 595 Protein_342 methyltransferase domain-containing protein -
  DV131_RS01950 comGG/cglG 340281..340694 (-) 414 WP_000265615.1 competence type IV pilus minor pilin ComGG Machinery gene
  DV131_RS01955 comGF/cglF 340672..341133 (-) 462 WP_000250520.1 competence type IV pilus minor pilin ComGF Machinery gene
  DV131_RS01960 comGE/cglE 341096..341398 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  DV131_RS01965 comGD/cglD 341361..341795 (-) 435 WP_033606693.1 competence type IV pilus minor pilin ComGD Machinery gene
  DV131_RS01970 comGC/cglC 341758..342081 (-) 324 WP_000738628.1 comG operon protein ComGC Machinery gene
  DV131_RS01975 comGB/cglB 342083..343099 (-) 1017 WP_074017570.1 competence type IV pilus assembly protein ComGB Machinery gene
  DV131_RS01980 comGA/cglA/cilD 343047..343988 (-) 942 WP_000249555.1 competence type IV pilus ATPase ComGA Machinery gene
  DV131_RS01985 - 344063..344428 (-) 366 WP_000286415.1 DUF1033 family protein -
  DV131_RS01990 - 344579..345637 (-) 1059 WP_000649466.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11108.08 Da        Isoelectric Point: 9.7273

>NTDB_id=304685 DV131_RS01960 WP_000413382.1 341096..341398(-) (comGE/cglE) [Streptococcus pneumoniae strain M26368]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=304685 DV131_RS01960 WP_000413382.1 341096..341398(-) (comGE/cglE) [Streptococcus pneumoniae strain M26368]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCTTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

100

100

1
  comGE/cglE Streptococcus pneumoniae D39

100

100

1
  comGE/cglE Streptococcus pneumoniae R6

100

100

1
  comGE/cglE Streptococcus pneumoniae TIGR4

100

100

1
  comGE/cglE Streptococcus mitis NCTC 12261

98

100

0.98
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

44.444

90

0.4
  comYE Streptococcus mutans UA159

44.444

90

0.4

Multiple sequence alignment