Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   DV131_RS01975 Genome accession   NZ_CP031246
Coordinates   342083..343099 (-) Length   338 a.a.
NCBI ID   WP_074017570.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain M26368     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 337083..348099
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DV131_RS12050 - 337163..337294 (-) 132 WP_000768904.1 hypothetical protein -
  DV131_RS01935 - 337295..338485 (-) 1191 WP_000167766.1 acetate kinase -
  DV131_RS01940 comYH 338536..339489 (-) 954 WP_000345133.1 class I SAM-dependent methyltransferase Machinery gene
  DV131_RS01945 - 339550..340144 (-) 595 Protein_342 methyltransferase domain-containing protein -
  DV131_RS01950 comGG/cglG 340281..340694 (-) 414 WP_000265615.1 competence type IV pilus minor pilin ComGG Machinery gene
  DV131_RS01955 comGF/cglF 340672..341133 (-) 462 WP_000250520.1 competence type IV pilus minor pilin ComGF Machinery gene
  DV131_RS01960 comGE/cglE 341096..341398 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  DV131_RS01965 comGD/cglD 341361..341795 (-) 435 WP_033606693.1 competence type IV pilus minor pilin ComGD Machinery gene
  DV131_RS01970 comGC/cglC 341758..342081 (-) 324 WP_000738628.1 comG operon protein ComGC Machinery gene
  DV131_RS01975 comGB/cglB 342083..343099 (-) 1017 WP_074017570.1 competence type IV pilus assembly protein ComGB Machinery gene
  DV131_RS01980 comGA/cglA/cilD 343047..343988 (-) 942 WP_000249555.1 competence type IV pilus ATPase ComGA Machinery gene
  DV131_RS01985 - 344063..344428 (-) 366 WP_000286415.1 DUF1033 family protein -
  DV131_RS01990 - 344579..345637 (-) 1059 WP_000649466.1 zinc-dependent alcohol dehydrogenase family protein -
  DV131_RS01995 nagA 345800..346951 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38482.48 Da        Isoelectric Point: 9.6162

>NTDB_id=304688 DV131_RS01975 WP_074017570.1 342083..343099(-) (comGB/cglB) [Streptococcus pneumoniae strain M26368]
MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLDRSSLLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTI
VTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQGMELTQIFQMMQEQGSQLFKEI
GQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=304688 DV131_RS01975 WP_074017570.1 342083..343099(-) (comGB/cglB) [Streptococcus pneumoniae strain M26368]
ATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAAGCAAAAAAATATCATCACCCTATTTAA
CAATCTCTTTTCTAGCGGTTTTCATCTGGTGGAGACTATCTCCTTTTTAGATAGGAGTTCCTTGTTGGACAAGCAGTGTG
TGACCCAGATGCGTACAGGCTTGTCTCAGGGGAAATCATTCTCAGAAATGATGGAAAGTTTGGGATGTTCAAGTACCATT
GTCACTCAGTTATCTCTAGCTGAAGTTCATGGCAATCTTCACCTGAGTTTGGGAAAGATAGAAGAATATCTAGACAATCT
GGCCAAGGTCAAGAAAAAATTGATTGAAGTAGCGACCTATCCTTTGATTTTGCTGGGTTTTCTTCTCTTAATTATGCTGG
GGCTACGGAATTACCTGCTCCCACAACTGGATAGTAGCAATATTGCCACCCGAATTATCGGTAATCTGCCACAAATTTTT
CTAGGCATGGTAGGGCTTGTTTCCGTGCTTGCCCTTTTAGCACTAACTTTTTATAAAAGAAGTTCTAAGATGAGTGTCTT
TTCTATCTTAGCACGCCTTCCCTTTATTGGAATATTTGTGCAGACCTACTTGACAGCCTATTATGCACGTGAATGGGGGA
ATATGATTTCACAGGGAATGGAGCTGACGCAGATTTTTCAAATGATGCAGGAACAAGGTTCCCAGCTCTTTAAAGAAATC
GGTCAAGATCTGGCTCAAACCCTGAAAAATGGCCGTGAATTTTCTCAGACGATAGGAACCTATCCTTTCTTTAGGAAGGA
ATTGAGTCTCATCATAGAGTATGGGGAAGTTAAGTCCAAGCTGGGTAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACCATGAATTTGGTGCAGCCACTGGTTTTTATTTTTGTGGCACTGATTATCGTT
TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus pneumoniae Rx1

98.521

100

0.985
  comGB/cglB Streptococcus pneumoniae D39

98.521

100

0.985
  comGB/cglB Streptococcus pneumoniae R6

98.521

100

0.985
  comGB/cglB Streptococcus pneumoniae TIGR4

98.521

100

0.985
  comGB/cglB Streptococcus mitis SK321

94.97

100

0.95
  comGB/cglB Streptococcus mitis NCTC 12261

94.083

100

0.941
  comYB Streptococcus gordonii str. Challis substr. CH1

70.536

99.408

0.701
  comYB Streptococcus mutans UA140

58.176

94.083

0.547
  comYB Streptococcus mutans UA159

58.176

94.083

0.547
  comGB Lactococcus lactis subsp. cremoris KW2

50.898

98.817

0.503

Multiple sequence alignment