Detailed information NTG0292257

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: DF184_RS00750
• Genome accession: NZ_CP029398
• Coordinates: 117387..117668 (+)
• Length: 93 a.a.
• NCBI ID: WP_024385124.1
• Uniprot ID: A0A0Z8HXH6
• Organism: Streptococcus suis strain HN105
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 112387..122668

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DF184_RS00730 (DF184_00730)	-	114050..114415 (+)	366	WP_002936568.1	DUF1033 family protein	-
DF184_RS00735 (DF184_00735)	-	114450..115400 (-)	951	WP_109371021.1	S66 peptidase family protein	-
DF184_RS00740 (DF184_00740)	comYA	115486..116436 (+)	951	WP_024410900.1	competence type IV pilus ATPase ComGA	Machinery gene
DF184_RS00745 (DF184_00745)	comYB	116348..117385 (+)	1038	WP_275425327.1	competence type IV pilus assembly protein ComGB	Machinery gene
DF184_RS00750 (DF184_00750)	comYC	117387..117668 (+)	282	WP_024385124.1	competence type IV pilus major pilin ComGC	Machinery gene
DF184_RS00755 (DF184_00755)	comGD	117649..118056 (+)	408	WP_109371023.1	competence type IV pilus minor pilin ComGD	-
DF184_RS00760 (DF184_00760)	comYE	118028..118321 (+)	294	WP_044752980.1	competence type IV pilus minor pilin ComGE	Machinery gene
DF184_RS00765 (DF184_00765)	comGF/cglF	118308..118742 (+)	435	WP_052506926.1	competence type IV pilus minor pilin ComGF	Machinery gene
DF184_RS00770 (DF184_00770)	comGG	118720..119130 (+)	411	WP_109371025.1	competence type IV pilus minor pilin ComGG	-
DF184_RS00775 (DF184_00775)	comYH	119187..120140 (+)	954	WP_109371027.1	class I SAM-dependent methyltransferase	Machinery gene
DF184_RS00780 (DF184_00780)	-	120190..121377 (+)	1188	WP_014637319.1	acetate kinase	-
DF184_RS00785 (DF184_00785)	-	121638..122189 (+)	552	WP_014637320.1	folate family ECF transporter S component	-

Sequence

Protein

• Length: 93 a.a.
• Molecular weight: 10474.44 Da
• Isoelectric Point: 6.3464

>NTDB_id=292257 DF184_RS00750 WP_024385124.1 117387..117668(+) (comYC) [Streptococcus suis strain HN105]
MKKLIEMKVKGFTLVEMLVVLGIISLLLLLFVPNLSQQKDAIQKKGDAAVVKVVESQMELYELEYDKEATVEDLQKAGYI
TPKQAEQYATAKK

Nucleotide

• Length: 282 bp

>NTDB_id=292257 DF184_RS00750 WP_024385124.1 117387..117668(+) (comYC) [Streptococcus suis strain HN105]
ATGAAAAAATTAATTGAAATGAAGGTAAAAGGGTTCACTCTGGTGGAAATGTTAGTCGTTTTGGGGATCATTAGCCTGCT
CTTGCTCCTCTTTGTGCCAAATTTGAGCCAGCAGAAGGATGCTATTCAGAAGAAGGGGGATGCGGCTGTTGTCAAAGTAG
TGGAGAGTCAAATGGAGCTCTATGAATTGGAATATGATAAGGAAGCAACGGTGGAGGACTTGCAAAAGGCTGGTTATATT
ACACCAAAACAAGCGGAGCAGTATGCTACGGCGAAAAAATAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (8-30)

3D structure

• AlphaFold DB: A0A0Z8HXH6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus suis isolate S10	91.398	100	0.914
comGC/cglC	Streptococcus pneumoniae TIGR4	60.87	98.925	0.602
comGC/cglC	Streptococcus pneumoniae Rx1	60.87	98.925	0.602
comGC/cglC	Streptococcus pneumoniae D39	60.87	98.925	0.602
comGC/cglC	Streptococcus pneumoniae R6	60.87	98.925	0.602
comGC/cglC	Streptococcus mitis NCTC 12261	60.87	98.925	0.602
comGC/cglC	Streptococcus mitis SK321	60.87	98.925	0.602
comYC	Streptococcus gordonii str. Challis substr. CH1	61.798	95.699	0.591
comYC	Streptococcus mutans UA140	59.091	94.624	0.559
comYC	Streptococcus mutans UA159	59.091	94.624	0.559
comGC	Lactococcus lactis subsp. cremoris KW2	56.818	94.624	0.538
comGC	Staphylococcus aureus MW2	48.649	79.57	0.387
comGC	Staphylococcus aureus N315	48.649	79.57	0.387
comGC	Bacillus subtilis subsp. subtilis str. 168	46.667	80.645	0.376