Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   DF184_RS00740 Genome accession   NZ_CP029398
Coordinates   115486..116436 (+) Length   316 a.a.
NCBI ID   WP_024410900.1    Uniprot ID   -
Organism   Streptococcus suis strain HN105     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 110486..121436
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DF184_RS00730 (DF184_00730) - 114050..114415 (+) 366 WP_002936568.1 DUF1033 family protein -
  DF184_RS00735 (DF184_00735) - 114450..115400 (-) 951 WP_109371021.1 S66 peptidase family protein -
  DF184_RS00740 (DF184_00740) comYA 115486..116436 (+) 951 WP_024410900.1 competence type IV pilus ATPase ComGA Machinery gene
  DF184_RS00745 (DF184_00745) comYB 116348..117385 (+) 1038 WP_275425327.1 competence type IV pilus assembly protein ComGB Machinery gene
  DF184_RS00750 (DF184_00750) comYC 117387..117668 (+) 282 WP_024385124.1 competence type IV pilus major pilin ComGC Machinery gene
  DF184_RS00755 (DF184_00755) comGD 117649..118056 (+) 408 WP_109371023.1 competence type IV pilus minor pilin ComGD -
  DF184_RS00760 (DF184_00760) comYE 118028..118321 (+) 294 WP_044752980.1 competence type IV pilus minor pilin ComGE Machinery gene
  DF184_RS00765 (DF184_00765) comGF/cglF 118308..118742 (+) 435 WP_052506926.1 competence type IV pilus minor pilin ComGF Machinery gene
  DF184_RS00770 (DF184_00770) comGG 118720..119130 (+) 411 WP_109371025.1 competence type IV pilus minor pilin ComGG -
  DF184_RS00775 (DF184_00775) comYH 119187..120140 (+) 954 WP_109371027.1 class I SAM-dependent methyltransferase Machinery gene
  DF184_RS00780 (DF184_00780) - 120190..121377 (+) 1188 WP_014637319.1 acetate kinase -

Sequence

Protein


Download         Length: 316 a.a.        Molecular weight: 35484.37 Da        Isoelectric Point: 5.4744

>NTDB_id=292255 DF184_RS00740 WP_024410900.1 115486..116436(+) (comYA) [Streptococcus suis strain HN105]
MIQEKARKMIEEAVADRVSDIYLVPRGECYQVYHRIMDEREFVQDLAEEEVTAIISHFKFLAGLNVGEKRRSQQGSCDYD
YGSGEISLRLSTVGDYRGKESLVIRLLYDNDKELKFWFEAAERLAEEIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
ILTIEDPVEIKQEDMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVIRASLTGATVFSTVHARSISGVY
ARMLELGVSPEELNNALQGIAYQRLIGGGGVVDFAKGNYQNHSADQWNVQIDRLFAAGHISLRQAETEKITLGSPA

Nucleotide


Download         Length: 951 bp        

>NTDB_id=292255 DF184_RS00740 WP_024410900.1 115486..116436(+) (comYA) [Streptococcus suis strain HN105]
ATGATTCAAGAAAAAGCAAGAAAGATGATTGAAGAGGCGGTGGCGGATAGGGTCAGTGACATCTATCTAGTTCCTCGAGG
TGAGTGTTACCAAGTCTATCATCGTATCATGGACGAGCGGGAATTTGTGCAAGACTTGGCTGAGGAGGAAGTAACAGCCA
TCATCAGCCATTTCAAGTTTTTAGCAGGTTTAAATGTTGGTGAAAAACGCCGTAGCCAGCAGGGTTCCTGTGACTATGAT
TATGGGAGCGGAGAGATTTCACTTCGCTTATCAACTGTCGGAGATTATCGTGGCAAGGAAAGTTTGGTTATCCGCCTGCT
CTATGACAATGACAAGGAACTCAAGTTCTGGTTTGAGGCGGCCGAGCGGCTTGCAGAAGAAATCAAGGGACGAGGGCTCT
ACCTTTTTTCGGGTCCAGTCGGCTCTGGTAAGACCACGCTCATGTATCATCTTGCCAGGCTGAAGTTTCCAGACAAGCAA
ATTTTGACCATCGAGGATCCTGTCGAAATCAAGCAGGAGGACATGCTGCAACTCCAGCTCAATGAAGCCATCGGAGCCAC
CTACGATAATCTGATCAAACTGTCCCTCCGTCATCGACCAGACTTGCTCATTATCGGTGAAATTCGGGATGCGGAAACGG
CACGGGCGGTCATCAGGGCCAGCCTGACGGGAGCTACCGTTTTCTCAACAGTCCATGCAAGGTCTATTTCAGGTGTCTAT
GCCCGTATGTTGGAACTGGGGGTCAGTCCTGAAGAGCTAAATAATGCCCTTCAAGGTATTGCCTATCAACGTTTAATCGG
GGGAGGAGGTGTAGTGGATTTTGCAAAAGGAAATTACCAAAACCATTCCGCAGACCAGTGGAATGTGCAAATTGATCGCC
TTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTACCCTTGGCTCGCCAGCGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

69.032

98.101

0.677
  comYA Streptococcus mutans UA159

67.846

98.418

0.668
  comYA Streptococcus mutans UA140

67.846

98.418

0.668
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

65.273

98.418

0.642
  comGA/cglA/cilD Streptococcus pneumoniae D39

65.273

98.418

0.642
  comGA/cglA/cilD Streptococcus pneumoniae R6

65.273

98.418

0.642
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

65.273

98.418

0.642
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

64.952

98.418

0.639
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

64.839

98.101

0.636
  comGA Lactococcus lactis subsp. cremoris KW2

53.312

100

0.535
  comGA Latilactobacillus sakei subsp. sakei 23K

41.155

87.658

0.361

Multiple sequence alignment