Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   DF184_RS00745 Genome accession   NZ_CP029398
Coordinates   116348..117385 (+) Length   345 a.a.
NCBI ID   WP_275425327.1    Uniprot ID   -
Organism   Streptococcus suis strain HN105     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 111348..122385
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DF184_RS00730 (DF184_00730) - 114050..114415 (+) 366 WP_002936568.1 DUF1033 family protein -
  DF184_RS00735 (DF184_00735) - 114450..115400 (-) 951 WP_109371021.1 S66 peptidase family protein -
  DF184_RS00740 (DF184_00740) comYA 115486..116436 (+) 951 WP_024410900.1 competence type IV pilus ATPase ComGA Machinery gene
  DF184_RS00745 (DF184_00745) comYB 116348..117385 (+) 1038 WP_275425327.1 competence type IV pilus assembly protein ComGB Machinery gene
  DF184_RS00750 (DF184_00750) comYC 117387..117668 (+) 282 WP_024385124.1 competence type IV pilus major pilin ComGC Machinery gene
  DF184_RS00755 (DF184_00755) comGD 117649..118056 (+) 408 WP_109371023.1 competence type IV pilus minor pilin ComGD -
  DF184_RS00760 (DF184_00760) comYE 118028..118321 (+) 294 WP_044752980.1 competence type IV pilus minor pilin ComGE Machinery gene
  DF184_RS00765 (DF184_00765) comGF/cglF 118308..118742 (+) 435 WP_052506926.1 competence type IV pilus minor pilin ComGF Machinery gene
  DF184_RS00770 (DF184_00770) comGG 118720..119130 (+) 411 WP_109371025.1 competence type IV pilus minor pilin ComGG -
  DF184_RS00775 (DF184_00775) comYH 119187..120140 (+) 954 WP_109371027.1 class I SAM-dependent methyltransferase Machinery gene
  DF184_RS00780 (DF184_00780) - 120190..121377 (+) 1188 WP_014637319.1 acetate kinase -
  DF184_RS00785 (DF184_00785) - 121638..122189 (+) 552 WP_014637320.1 folate family ECF transporter S component -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 38917.89 Da        Isoelectric Point: 8.7089

>NTDB_id=292256 DF184_RS00745 WP_275425327.1 116348..117385(+) (comYB) [Streptococcus suis strain HN105]
MCKLIAFLQQDISVFGRQKQKKLPLARQRKVIELFNNLFASGFHLGEIVDFLKRSQLLADPYTQVLSDGLLAGKPFSSLL
ADLRFSDAVVTQVALAEVHGNTSLSLSHIQSYLENVSKVRKKLIEVATYPIILLGFLLLIMLGLKNYLLPQLEEGNAATV
LINHLPTIFLSLCGLSLVAVLAGLVWFRKTNKIKVFSCLAALPFFGKLIQTYLTAYYAREWGSLIGQGLDLPQIVGLMQE
QQSQLFREIGQDLEQSLSNGQSFHEHIKTYTFFKRELSLIVEYGQVKSKLGSELTVYAAECWEDFFSRVNRAMQLIQPLV
FLFVALMVVLIYAAMLLPIYQNMEL

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=292256 DF184_RS00745 WP_275425327.1 116348..117385(+) (comYB) [Streptococcus suis strain HN105]
ATGTGCAAATTGATCGCCTTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTACCCTTGGCTCG
CCAGCGTAAGGTCATTGAGCTTTTCAATAATCTTTTTGCCAGTGGTTTTCATCTGGGGGAGATTGTTGATTTCCTCAAAC
GCAGTCAGCTTCTGGCAGATCCCTATACCCAGGTCTTGTCAGACGGGCTGTTAGCAGGCAAACCCTTTTCAAGTTTGCTG
GCGGATTTGCGTTTTTCAGATGCGGTGGTCACACAGGTAGCTCTGGCAGAGGTTCATGGCAATACTAGTCTGAGTTTGAG
CCATATCCAGTCCTATCTGGAAAATGTCAGCAAGGTTCGTAAAAAGCTGATTGAGGTGGCGACCTATCCGATTATATTGC
TTGGTTTTTTACTCTTGATTATGCTGGGCTTGAAAAACTATCTTCTGCCCCAGTTGGAGGAAGGCAATGCAGCGACCGTG
CTGATCAATCATCTACCGACTATCTTTTTATCCCTCTGTGGACTTAGTTTGGTGGCGGTCTTAGCTGGTCTTGTTTGGTT
TCGCAAAACTAACAAAATCAAGGTCTTTTCCTGCTTAGCAGCTCTGCCATTTTTCGGAAAACTCATCCAAACCTATCTGA
CGGCCTATTACGCCAGGGAGTGGGGGAGTTTGATTGGGCAAGGCTTGGACCTGCCGCAGATTGTGGGTTTGATGCAGGAG
CAGCAATCGCAGCTCTTTCGGGAGATTGGACAGGACCTGGAGCAGTCGCTTTCCAATGGTCAGAGTTTTCACGAACACAT
CAAGACCTACACCTTTTTTAAGCGGGAGCTGAGTTTGATCGTCGAATATGGTCAGGTCAAGTCCAAGTTGGGAAGCGAGT
TGACAGTCTATGCAGCCGAGTGTTGGGAGGATTTTTTCTCTCGGGTCAATAGAGCCATGCAGCTGATTCAACCGCTGGTC
TTTCTCTTTGTGGCCCTAATGGTCGTTCTCATCTACGCAGCCATGTTGCTGCCGATTTATCAAAATATGGAGTTGTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)

Type II secretion system (T2SS), protein F (T2SSF)

(33-150)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

63.743

99.13

0.632
  comGB/cglB Streptococcus mitis NCTC 12261

61.194

97.101

0.594
  comGB/cglB Streptococcus mitis SK321

60.896

97.101

0.591
  comYB Streptococcus mutans UA140

59.184

99.42

0.588
  comYB Streptococcus mutans UA159

59.184

99.42

0.588
  comGB/cglB Streptococcus pneumoniae Rx1

60.597

97.101

0.588
  comGB/cglB Streptococcus pneumoniae D39

60.597

97.101

0.588
  comGB/cglB Streptococcus pneumoniae R6

60.597

97.101

0.588
  comGB/cglB Streptococcus pneumoniae TIGR4

60.597

97.101

0.588
  comGB Lactococcus lactis subsp. cremoris KW2

50.445

97.681

0.493

Multiple sequence alignment