Detailed information NTG0253703

Bioinformatically predicted

Overview

• Name: comGC
• Type: Machinery gene
• Locus tag: DK181_RS00920
• Genome accession: NZ_CP029490
• Coordinates: 155640..155966 (+)
• Length: 108 a.a.
• NCBI ID: WP_019770073.1
• Uniprot ID: A0ABM6W496
• Organism: Streptococcus sobrinus strain SL1
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 150640..160966

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DK181_RS00905 (DK182_00905)	-	152935..153303 (+)	369	WP_019781971.1	DUF1033 family protein	-
DK181_RS00910 (DK182_00910)	comGA/cglA	153729..154676 (+)	948	WP_002959503.1	competence type IV pilus ATPase ComGA	Machinery gene
DK181_RS00915 (DK182_00915)	comGB	154600..155643 (+)	1044	WP_002959504.1	competence type IV pilus assembly protein ComGB	Machinery gene
DK181_RS00920 (DK182_00920)	comGC	155640..155966 (+)	327	WP_019770073.1	competence type IV pilus major pilin ComGC	Machinery gene
DK181_RS00925 (DK182_00925)	comGD	155920..156354 (+)	435	WP_254051091.1	competence type IV pilus minor pilin ComGD	Machinery gene
DK181_RS00930 (DK182_00930)	comGE	156326..156619 (+)	294	WP_002959510.1	competence type IV pilus minor pilin ComGE	Machinery gene
DK181_RS00935 (DK182_00935)	comGF	156603..157040 (+)	438	WP_002959513.1	competence type IV pilus minor pilin ComGF	Machinery gene
DK181_RS00940 (DK182_00940)	comGG	157018..157479 (+)	462	WP_002959515.1	competence type IV pilus minor pilin ComGG	Machinery gene
DK181_RS00950 (DK182_00950)	-	157681..157947 (+)	267	WP_002959516.1	type II toxin-antitoxin system RelE/ParE family toxin	-
DK181_RS00955 (DK182_00955)	-	157934..158209 (+)	276	WP_002959518.1	helix-turn-helix domain-containing protein	-
DK181_RS00960 (DK182_00960)	comGH	158308..159261 (+)	954	WP_019771347.1	class I SAM-dependent methyltransferase	Machinery gene
DK181_RS00965 (DK182_00965)	-	159324..160520 (+)	1197	WP_002959522.1	acetate kinase	-

Sequence

Protein

• Length: 108 a.a.
• Molecular weight: 12196.32 Da
• Isoelectric Point: 10.1213

>NTDB_id=253703 DK181_RS00920 WP_019770073.1 155640..155966(+) (comGC) [Streptococcus sobrinus strain SL1]
MMKKFLKRLKGKKVKAFTLIEMLVVLLIISVLLLLFVPNLAKQKDKVKDTGGSAVVKVVESQAELYELNHSDDATVSKLV
SDGDITQKQADSYNDYYKKHKESRNVPN

Nucleotide

• Length: 327 bp

>NTDB_id=253703 DK181_RS00920 WP_019770073.1 155640..155966(+) (comGC) [Streptococcus sobrinus strain SL1]
ATGATGAAAAAATTTCTCAAACGCCTAAAAGGCAAGAAGGTCAAAGCCTTCACCCTGATTGAAATGCTGGTCGTGCTACT
GATTATCAGCGTTTTGCTCCTGCTCTTTGTCCCCAATTTGGCCAAGCAAAAGGATAAGGTCAAGGATACTGGCGGTTCAG
CCGTTGTCAAGGTGGTGGAAAGTCAGGCGGAACTCTATGAACTCAATCATAGCGATGATGCCACGGTATCAAAACTAGTT
TCTGATGGTGACATCACCCAAAAACAGGCGGATTCTTACAATGATTATTACAAGAAACATAAGGAAAGTCGCAACGTTCC
GAACTAG

Domains

Predicted by InterProScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (12-35)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC	Streptococcus mutans UA140	75.962	96.296	0.731
comGC	Streptococcus mutans UA159	75.962	96.296	0.731
comGC	Streptococcus gordonii str. Challis substr. CH1	68.571	97.222	0.667
comGC/cglC	Streptococcus mitis SK321	68.687	91.667	0.63
comGC/cglC	Streptococcus mitis NCTC 12261	63.551	99.074	0.63
comGC/cglC	Streptococcus pneumoniae TIGR4	64.646	91.667	0.593
comGC/cglC	Streptococcus pneumoniae Rx1	64.646	91.667	0.593
comGC/cglC	Streptococcus pneumoniae D39	64.646	91.667	0.593
comGC/cglC	Streptococcus pneumoniae R6	64.646	91.667	0.593
comGC	Lactococcus lactis subsp. cremoris KW2	62.376	93.519	0.583
comGC	Streptococcus suis isolate S10	63.636	81.481	0.519
comGC	Staphylococcus aureus MW2	50.562	82.407	0.417
comGC	Staphylococcus aureus N315	50.562	82.407	0.417