Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB   Type   Machinery gene
Locus tag   DK181_RS00915 Genome accession   NZ_CP029490
Coordinates   154600..155643 (+) Length   347 a.a.
NCBI ID   WP_002959504.1    Uniprot ID   -
Organism   Streptococcus sobrinus strain SL1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 149600..160643
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK181_RS00895 (DK182_00895) - 149608..149970 (-) 363 WP_002959493.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  DK181_RS00900 (DK182_00900) - 150331..152715 (-) 2385 WP_019771344.1 HAD-IC family P-type ATPase -
  DK181_RS00905 (DK182_00905) - 152935..153303 (+) 369 WP_019781971.1 DUF1033 family protein -
  DK181_RS00910 (DK182_00910) comGA/cglA 153729..154676 (+) 948 WP_002959503.1 competence type IV pilus ATPase ComGA Machinery gene
  DK181_RS00915 (DK182_00915) comGB 154600..155643 (+) 1044 WP_002959504.1 competence type IV pilus assembly protein ComGB Machinery gene
  DK181_RS00920 (DK182_00920) comGC 155640..155966 (+) 327 WP_019770073.1 competence type IV pilus major pilin ComGC Machinery gene
  DK181_RS00925 (DK182_00925) comGD 155920..156354 (+) 435 WP_254051091.1 competence type IV pilus minor pilin ComGD Machinery gene
  DK181_RS00930 (DK182_00930) comGE 156326..156619 (+) 294 WP_002959510.1 competence type IV pilus minor pilin ComGE Machinery gene
  DK181_RS00935 (DK182_00935) comGF 156603..157040 (+) 438 WP_002959513.1 competence type IV pilus minor pilin ComGF Machinery gene
  DK181_RS00940 (DK182_00940) comGG 157018..157479 (+) 462 WP_002959515.1 competence type IV pilus minor pilin ComGG Machinery gene
  DK181_RS00950 (DK182_00950) - 157681..157947 (+) 267 WP_002959516.1 type II toxin-antitoxin system RelE/ParE family toxin -
  DK181_RS00955 (DK182_00955) - 157934..158209 (+) 276 WP_002959518.1 helix-turn-helix domain-containing protein -
  DK181_RS00960 (DK182_00960) comGH 158308..159261 (+) 954 WP_019771347.1 class I SAM-dependent methyltransferase Machinery gene
  DK181_RS00965 (DK182_00965) - 159324..160520 (+) 1197 WP_002959522.1 acetate kinase -

Sequence

Protein


Download         Length: 347 a.a.        Molecular weight: 40128.76 Da        Isoelectric Point: 10.1589

>NTDB_id=253702 DK181_RS00915 WP_002959504.1 154600..155643(+) (comGB) [Streptococcus sobrinus strain SL1]
MKKLTNFLQQDISLRKRRPPKKLKTSRQRKVIQLFNNLLESGFTLTEIVDFLDRSSLLAPAYTKEMRASLLAGENLAAMM
GKLGFSDDVVTQLSLAELHGNTQGSLLKIEAYLAHLMTVKRKLWEVATYPIILLTFLILIMLGLRNYLLPQLERTNLATR
IINHFPLVFLIGVLVLALVILCLIWLQRRSRKITWYSRLARLPLLGRFVQLYLTAYYAREWGNLIGQGVEMSRIVQLMQE
QRSQLFQEIGREMEAALLAGQEFHHKVLDYPFFLRELSLIIEYGQVKSKLGSELEVYAQETWEAFFSRVNRATQLIQPLV
FILVALVIVMIYAAMLLPMYHNMEVPL

Nucleotide


Download         Length: 1044 bp        

>NTDB_id=253702 DK181_RS00915 WP_002959504.1 154600..155643(+) (comGB) [Streptococcus sobrinus strain SL1]
ATGAAAAAATTGACCAACTTCTTGCAGCAGGACATCTCACTGAGGAAGAGGCGGCCGCCGAAAAAATTAAAGACTAGCCG
GCAGCGTAAGGTCATCCAACTCTTCAATAATCTTCTGGAGTCGGGCTTTACCCTAACCGAGATTGTGGATTTTCTGGACC
GCAGTAGCCTTCTGGCTCCGGCCTATACCAAGGAGATGCGGGCCTCCCTCTTGGCGGGGGAAAATTTGGCAGCTATGATG
GGCAAGTTAGGCTTTTCCGATGATGTGGTCACTCAGCTTTCTCTGGCAGAACTGCATGGCAATACCCAAGGCAGTCTCCT
GAAAATCGAGGCTTATCTAGCCCACCTCATGACTGTTAAAAGGAAGCTTTGGGAGGTCGCTACCTATCCCATTATTCTTC
TAACCTTTTTGATTCTGATTATGCTGGGCCTGCGAAATTATCTCTTACCCCAGTTGGAAAGGACCAACCTGGCGACCAGG
ATAATCAATCATTTTCCTCTGGTCTTTCTAATTGGAGTACTGGTTTTGGCCTTAGTCATTCTTTGCTTGATCTGGTTACA
AAGACGGTCGCGAAAAATCACCTGGTACAGCCGCCTGGCTAGACTCCCTTTGCTGGGAAGATTTGTCCAACTCTACTTGA
CTGCCTATTATGCTAGGGAGTGGGGCAATTTGATTGGTCAGGGGGTAGAAATGAGTCGGATTGTCCAACTTATGCAAGAG
CAAAGATCCCAACTCTTCCAGGAGATTGGCCGAGAGATGGAGGCGGCTCTTCTAGCTGGTCAAGAATTCCACCACAAGGT
TTTGGACTATCCCTTCTTCCTTCGGGAATTGAGCCTGATTATTGAATATGGTCAGGTCAAATCTAAATTAGGTAGTGAGC
TGGAGGTCTATGCTCAGGAGACCTGGGAGGCCTTCTTTAGTCGGGTCAATCGAGCTACTCAGTTGATTCAGCCCTTAGTC
TTTATTCTGGTGGCCCTTGTTATCGTCATGATTTACGCAGCCATGTTGCTGCCCATGTATCACAATATGGAGGTACCTTT
ATGA

Domains

Predicted by InterProScan.

Type II secretion system (T2SS), protein F (T2SSF)

(32-150)

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB Streptococcus mutans UA159

66.082

98.559

0.651
  comGB Streptococcus mutans UA140

65.789

98.559

0.648
  comGB Streptococcus gordonii str. Challis substr. CH1

61.628

99.135

0.611
  comGB/cglB Streptococcus mitis NCTC 12261

60.597

96.542

0.585
  comGB/cglB Streptococcus mitis SK321

59.701

96.542

0.576
  comGB/cglB Streptococcus pneumoniae Rx1

59.104

96.542

0.571
  comGB/cglB Streptococcus pneumoniae D39

59.104

96.542

0.571
  comGB/cglB Streptococcus pneumoniae R6

59.104

96.542

0.571
  comGB/cglB Streptococcus pneumoniae TIGR4

59.104

96.542

0.571
  comGB Lactococcus lactis subsp. cremoris KW2

51.032

97.695

0.499

Multiple sequence alignment