Detailed information NTG0253706

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: DK181_RS00935
• Genome accession: NZ_CP029490
• Coordinates: 156603..157040 (+)
• Length: 145 a.a.
• NCBI ID: WP_002959513.1
• Uniprot ID: A0ABM6W3M9
• Organism: Streptococcus sobrinus strain SL1
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 151603..162040

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DK181_RS00905 (DK182_00905)	-	152935..153303 (+)	369	WP_019781971.1	DUF1033 family protein	-
DK181_RS00910 (DK182_00910)	comGA/cglA	153729..154676 (+)	948	WP_002959503.1	competence type IV pilus ATPase ComGA	Machinery gene
DK181_RS00915 (DK182_00915)	comGB	154600..155643 (+)	1044	WP_002959504.1	competence type IV pilus assembly protein ComGB	Machinery gene
DK181_RS00920 (DK182_00920)	comGC	155640..155966 (+)	327	WP_019770073.1	competence type IV pilus major pilin ComGC	Machinery gene
DK181_RS00925 (DK182_00925)	comGD	155920..156354 (+)	435	WP_254051091.1	competence type IV pilus minor pilin ComGD	Machinery gene
DK181_RS00930 (DK182_00930)	comGE	156326..156619 (+)	294	WP_002959510.1	competence type IV pilus minor pilin ComGE	Machinery gene
DK181_RS00935 (DK182_00935)	comGF	156603..157040 (+)	438	WP_002959513.1	competence type IV pilus minor pilin ComGF	Machinery gene
DK181_RS00940 (DK182_00940)	comGG	157018..157479 (+)	462	WP_002959515.1	competence type IV pilus minor pilin ComGG	Machinery gene
DK181_RS00950 (DK182_00950)	-	157681..157947 (+)	267	WP_002959516.1	type II toxin-antitoxin system RelE/ParE family toxin	-
DK181_RS00955 (DK182_00955)	-	157934..158209 (+)	276	WP_002959518.1	helix-turn-helix domain-containing protein	-
DK181_RS00960 (DK182_00960)	comGH	158308..159261 (+)	954	WP_019771347.1	class I SAM-dependent methyltransferase	Machinery gene
DK181_RS00965 (DK182_00965)	-	159324..160520 (+)	1197	WP_002959522.1	acetate kinase	-
DK181_RS00970 (DK182_00970)	-	160998..161903 (+)	906	WP_002959524.1	LysR family transcriptional regulator	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16245.67 Da
• Isoelectric Point: 8.2388

>NTDB_id=253706 DK181_RS00935 WP_002959513.1 156603..157040(+) (comGF) [Streptococcus sobrinus strain SL1]
MWLKTRIRAFTLLECLVALLVIAGSVMVYQGLTQVLTSNVAYISKNDEEDWLLFCQQLRSELSGTDLDRVADNKLYVKKG
DQPLAFGQSRSDDFRKTNADGRGYQPMLFGLKACTISQTGQTVTISLTLKSGLERTFVYDFAKTS

Nucleotide

• Length: 438 bp

>NTDB_id=253706 DK181_RS00935 WP_002959513.1 156603..157040(+) (comGF) [Streptococcus sobrinus strain SL1]
ATGTGGCTAAAAACTAGAATTCGAGCCTTCACCCTCTTGGAGTGCTTGGTGGCCCTCTTGGTCATCGCTGGCAGTGTCAT
GGTCTATCAGGGGCTAACCCAGGTTTTGACCAGCAATGTTGCCTACATCAGCAAGAATGATGAGGAGGACTGGCTCCTCT
TTTGTCAGCAGCTTCGCTCAGAGCTATCTGGGACTGACTTGGACCGGGTGGCGGACAATAAACTTTATGTCAAAAAGGGT
GACCAGCCTCTAGCCTTTGGCCAGTCCCGCTCGGATGATTTTCGCAAGACCAATGCTGACGGCCGGGGCTATCAGCCCAT
GCTCTTTGGCCTCAAGGCCTGCACCATCAGCCAGACTGGTCAGACCGTCACTATTTCGCTGACTCTGAAATCAGGCTTAG
AAAGGACCTTTGTCTATGATTTTGCAAAAACGTCTTAG

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (43-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA140	64.029	95.862	0.614
comGF	Streptococcus mutans UA159	63.309	95.862	0.607
comGF	Lactococcus lactis subsp. cremoris KW2	51.049	98.621	0.503
comGF/cglF	Streptococcus mitis NCTC 12261	44.138	100	0.441
comGF/cglF	Streptococcus pneumoniae Rx1	45.652	95.172	0.434
comGF/cglF	Streptococcus pneumoniae D39	45.652	95.172	0.434
comGF/cglF	Streptococcus pneumoniae R6	45.652	95.172	0.434
comGF/cglF	Streptococcus pneumoniae TIGR4	45.652	95.172	0.434
comGF/cglF	Streptococcus mitis SK321	42.069	100	0.421