Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   DYB47_RS01340 Genome accession   NZ_UHFV01000002
Coordinates   232834..233775 (+) Length   313 a.a.
NCBI ID   WP_003079951.1    Uniprot ID   G5JWA7
Organism   Streptococcus macacae NCTC 11558     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 227834..238775
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DYB47_RS01330 (NCTC11558_00269) rpoC 228563..232198 (+) 3636 WP_172459284.1 DNA-directed RNA polymerase subunit beta' -
  DYB47_RS01335 (NCTC11558_00270) - 232360..232740 (+) 381 WP_003081066.1 DUF1033 family protein -
  DYB47_RS01340 (NCTC11558_00271) comYA 232834..233775 (+) 942 WP_003079951.1 competence type IV pilus ATPase ComGA Machinery gene
  DYB47_RS01345 (NCTC11558_00272) comYB 233699..234742 (+) 1044 WP_081479323.1 competence type IV pilus assembly protein ComGB Machinery gene
  DYB47_RS01350 (NCTC11558_00273) comYC 234742..235056 (+) 315 WP_003080278.1 competence type IV pilus major pilin ComGC Machinery gene
  DYB47_RS01355 (NCTC11558_00274) comYD 235043..235462 (+) 420 WP_003082165.1 competence type IV pilus minor pilin ComGD Machinery gene
  DYB47_RS01360 comYE 235416..235715 (+) 300 WP_040841662.1 competence type IV pilus minor pilin ComGE Machinery gene
  DYB47_RS01365 (NCTC11558_00276) comYF 235696..236127 (+) 432 WP_003079210.1 competence type IV pilus minor pilin ComGF Machinery gene
  DYB47_RS09855 (NCTC11558_00277) comYG 236108..236485 (+) 378 WP_040841664.1 competence type IV pilus minor pilin ComGG Machinery gene
  DYB47_RS01375 (NCTC11558_00278) comYH 236544..237503 (+) 960 WP_003080448.1 class I SAM-dependent methyltransferase Machinery gene
  DYB47_RS01380 (NCTC11558_00279) - 237558..238754 (+) 1197 WP_003081585.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35937.57 Da        Isoelectric Point: 9.1951

>NTDB_id=1171292 DYB47_RS01340 WP_003079951.1 232834..233775(+) (comYA) [Streptococcus macacae NCTC 11558]
MVQKLGKEIISKAVKEKVQDIYIVPKKDLYELYMRIGNERKFIDVYDHHLMVNLISHFKFVAGMNVGEKRRSQLGSCDYY
YNETNMVSLRLSTVGDYRGYESLVIRLLFDGRQDLHFWFNGVHQVLNAIRGRGLYLFSGPVGSGKTTLMYQIAREKFFNK
QIITIEDPVEIKEANMLQLQLNENIGMTYDSLIKLSLRHRPDILIIGEIRDRETARAVIRASLTGVLVMSTVHAKSIPGV
YARLLELGVNPKELENTLGGIIYQRLISGGGVLDFAKDKFQEHSAQKWNAQINRLFTEGYITEEEAEIEKIKN

Nucleotide


Download         Length: 942 bp        

>NTDB_id=1171292 DYB47_RS01340 WP_003079951.1 232834..233775(+) (comYA) [Streptococcus macacae NCTC 11558]
ATGGTTCAAAAATTAGGAAAGGAAATTATTAGCAAGGCGGTTAAGGAAAAAGTCCAAGATATTTATATTGTTCCTAAGAA
AGACTTGTATGAATTGTACATGAGGATAGGAAATGAAAGAAAATTTATTGATGTCTATGACCATCATCTCATGGTTAATC
TTATTAGCCACTTTAAATTTGTTGCAGGAATGAATGTTGGTGAAAAAAGAAGAAGTCAACTAGGTTCATGTGATTACTAT
TATAATGAGACTAACATGGTATCTTTAAGACTCTCTACAGTTGGTGATTATCGTGGCTATGAAAGTCTTGTCATTAGGCT
TTTATTTGATGGACGTCAAGATTTACATTTTTGGTTTAATGGTGTCCATCAGGTCTTAAATGCTATTAGAGGAAGAGGAC
TGTACTTATTTTCAGGTCCAGTAGGCAGTGGTAAAACAACTCTTATGTATCAAATAGCAAGGGAAAAATTCTTCAATAAA
CAAATTATTACTATTGAAGACCCTGTTGAAATAAAAGAAGCCAATATGCTGCAGCTGCAATTGAATGAAAATATCGGTAT
GACCTATGATAGTTTAATAAAGTTATCTTTAAGACATCGTCCTGATATTCTCATTATTGGAGAAATCCGCGATAGAGAAA
CGGCTAGAGCCGTTATCAGAGCTAGTTTAACAGGAGTACTTGTCATGTCAACCGTCCATGCTAAAAGTATCCCTGGAGTT
TATGCTAGATTGTTAGAATTAGGAGTCAATCCAAAAGAATTAGAAAATACTTTAGGTGGAATCATTTATCAGCGTTTAAT
AAGTGGGGGAGGTGTTTTAGATTTTGCAAAAGATAAATTTCAAGAGCATTCAGCACAAAAATGGAATGCTCAGATTAATA
GGCTTTTTACAGAAGGATATATTACTGAAGAGGAAGCTGAAATCGAAAAAATTAAGAACTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G5JWA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA140

75.719

100

0.757
  comYA Streptococcus mutans UA159

75.719

100

0.757
  comYA Streptococcus gordonii str. Challis substr. CH1

66.454

100

0.665
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

66.346

99.681

0.661
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.916

99.361

0.655
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

65.273

99.361

0.649
  comGA/cglA/cilD Streptococcus pneumoniae D39

65.273

99.361

0.649
  comGA/cglA/cilD Streptococcus pneumoniae R6

65.273

99.361

0.649
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

65.273

99.361

0.649
  comGA Lactococcus lactis subsp. cremoris KW2

54.341

99.361

0.54

Multiple sequence alignment