Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   DYB47_RS01345 Genome accession   NZ_UHFV01000002
Coordinates   233699..234742 (+) Length   347 a.a.
NCBI ID   WP_081479323.1    Uniprot ID   -
Organism   Streptococcus macacae NCTC 11558     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 228699..239742
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DYB47_RS01335 (NCTC11558_00270) - 232360..232740 (+) 381 WP_003081066.1 DUF1033 family protein -
  DYB47_RS01340 (NCTC11558_00271) comYA 232834..233775 (+) 942 WP_003079951.1 competence type IV pilus ATPase ComGA Machinery gene
  DYB47_RS01345 (NCTC11558_00272) comYB 233699..234742 (+) 1044 WP_081479323.1 competence type IV pilus assembly protein ComGB Machinery gene
  DYB47_RS01350 (NCTC11558_00273) comYC 234742..235056 (+) 315 WP_003080278.1 competence type IV pilus major pilin ComGC Machinery gene
  DYB47_RS01355 (NCTC11558_00274) comYD 235043..235462 (+) 420 WP_003082165.1 competence type IV pilus minor pilin ComGD Machinery gene
  DYB47_RS01360 comYE 235416..235715 (+) 300 WP_040841662.1 competence type IV pilus minor pilin ComGE Machinery gene
  DYB47_RS01365 (NCTC11558_00276) comYF 235696..236127 (+) 432 WP_003079210.1 competence type IV pilus minor pilin ComGF Machinery gene
  DYB47_RS09855 (NCTC11558_00277) comYG 236108..236485 (+) 378 WP_040841664.1 competence type IV pilus minor pilin ComGG Machinery gene
  DYB47_RS01375 (NCTC11558_00278) comYH 236544..237503 (+) 960 WP_003080448.1 class I SAM-dependent methyltransferase Machinery gene
  DYB47_RS01380 (NCTC11558_00279) - 237558..238754 (+) 1197 WP_003081585.1 acetate kinase -
  DYB47_RS01385 (NCTC11558_00280) - 238981..239658 (+) 678 WP_003080765.1 CPBP family intramembrane glutamic endopeptidase -

Sequence

Protein


Download         Length: 347 a.a.        Molecular weight: 40011.98 Da        Isoelectric Point: 10.1775

>NTDB_id=1171293 DYB47_RS01345 WP_081479323.1 233699..234742(+) (comYB) [Streptococcus macacae NCTC 11558]
MLRLIGFLQKDILLKRKLKSKKLRTKRQKKVIQLLNNLFTSGFNLPEIINFLDRSRLLSKIYIKEMRRGLLSGMGLAEIM
SSLGFSDDVVTQLALSEIHGNTQKSLLKIESYLENVMAVKKKLVEVATYPIILLVFLVLIMLGLKNYLFPQLEKGNAATQ
VITQFPTFFLLSVVIIMFLLSSLYLLSRKVKKIKLMAFYARLPFIGNYFQLYLTAYYAREWGNLIGQGVEMSHIVKLMQS
QKSQLFKEIGADMEQALLSGQGFHQKVLDYPFFLKELSLMIEYGEVKSKLGSELDIYAEETWESFFSKIQRVTQLIQPLV
FILVAFVIVMIYAAMLLPIYQNMEVHL

Nucleotide


Download         Length: 1044 bp        

>NTDB_id=1171293 DYB47_RS01345 WP_081479323.1 233699..234742(+) (comYB) [Streptococcus macacae NCTC 11558]
ATGCTCAGATTAATAGGCTTTTTACAGAAGGATATATTACTGAAGAGGAAGCTGAAATCGAAAAAATTAAGAACTAAAAG
ACAGAAAAAAGTGATTCAGCTGCTGAATAATCTTTTTACAAGCGGTTTTAATTTACCAGAGATTATTAATTTTCTTGATA
GAAGCCGTCTATTATCTAAAATTTATATTAAGGAAATGAGAAGAGGACTTTTAAGCGGTATGGGTTTAGCTGAAATCATG
AGTTCTTTGGGATTTTCAGATGATGTTGTTACACAATTAGCATTATCAGAAATTCACGGTAATACTCAAAAAAGTTTATT
AAAGATAGAATCATATTTAGAAAATGTTATGGCAGTTAAAAAGAAGCTGGTTGAAGTGGCTACCTATCCAATCATTTTAC
TTGTTTTTTTAGTACTTATTATGCTGGGATTGAAAAATTATTTATTTCCCCAACTTGAAAAAGGAAATGCAGCAACTCAG
GTGATTACCCAGTTTCCCACTTTCTTTTTGCTTAGTGTAGTCATTATTATGTTCCTGTTAAGTAGCCTGTACTTGCTGTC
ACGTAAAGTAAAGAAAATAAAATTAATGGCTTTTTATGCCAGACTGCCCTTTATTGGAAACTATTTTCAACTTTATTTAA
CAGCCTATTATGCACGAGAATGGGGCAATCTTATTGGTCAAGGGGTGGAAATGAGTCATATTGTAAAATTAATGCAGAGT
CAAAAATCCCAACTATTTAAAGAAATTGGAGCTGATATGGAGCAGGCTCTTTTATCTGGACAAGGCTTTCATCAAAAAGT
TTTGGATTATCCTTTTTTTCTTAAAGAACTGAGCTTAATGATTGAGTATGGTGAAGTAAAATCTAAGTTAGGCAGTGAAT
TAGATATTTATGCTGAAGAAACGTGGGAGTCTTTTTTTTCAAAAATTCAAAGGGTAACACAATTGATACAGCCCCTCGTT
TTTATTTTAGTCGCTTTTGTGATTGTCATGATTTATGCAGCTATGCTGTTACCCATTTATCAAAACATGGAGGTTCATTT
ATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(32-145)

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

74.194

98.271

0.729
  comYB Streptococcus mutans UA159

73.9

98.271

0.726
  comYB Streptococcus gordonii str. Challis substr. CH1

61.047

99.135

0.605
  comGB/cglB Streptococcus mitis NCTC 12261

58.284

97.406

0.568
  comGB/cglB Streptococcus pneumoniae Rx1

57.44

96.83

0.556
  comGB/cglB Streptococcus pneumoniae R6

57.44

96.83

0.556
  comGB/cglB Streptococcus pneumoniae TIGR4

57.44

96.83

0.556
  comGB/cglB Streptococcus pneumoniae D39

57.44

96.83

0.556
  comGB/cglB Streptococcus mitis SK321

57.143

96.83

0.553
  comGB Lactococcus lactis subsp. cremoris KW2

52.663

97.406

0.513

Multiple sequence alignment