Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   DYB47_RS01375 Genome accession   NZ_UHFV01000002
Coordinates   236544..237503 (+) Length   319 a.a.
NCBI ID   WP_003080448.1    Uniprot ID   G5JWB4
Organism   Streptococcus macacae NCTC 11558     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 231544..242503
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DYB47_RS01335 (NCTC11558_00270) - 232360..232740 (+) 381 WP_003081066.1 DUF1033 family protein -
  DYB47_RS01340 (NCTC11558_00271) comYA 232834..233775 (+) 942 WP_003079951.1 competence type IV pilus ATPase ComGA Machinery gene
  DYB47_RS01345 (NCTC11558_00272) comYB 233699..234742 (+) 1044 WP_081479323.1 competence type IV pilus assembly protein ComGB Machinery gene
  DYB47_RS01350 (NCTC11558_00273) comYC 234742..235056 (+) 315 WP_003080278.1 competence type IV pilus major pilin ComGC Machinery gene
  DYB47_RS01355 (NCTC11558_00274) comYD 235043..235462 (+) 420 WP_003082165.1 competence type IV pilus minor pilin ComGD Machinery gene
  DYB47_RS01360 comYE 235416..235715 (+) 300 WP_040841662.1 competence type IV pilus minor pilin ComGE Machinery gene
  DYB47_RS01365 (NCTC11558_00276) comYF 235696..236127 (+) 432 WP_003079210.1 competence type IV pilus minor pilin ComGF Machinery gene
  DYB47_RS09855 (NCTC11558_00277) comYG 236108..236485 (+) 378 WP_040841664.1 competence type IV pilus minor pilin ComGG Machinery gene
  DYB47_RS01375 (NCTC11558_00278) comYH 236544..237503 (+) 960 WP_003080448.1 class I SAM-dependent methyltransferase Machinery gene
  DYB47_RS01380 (NCTC11558_00279) - 237558..238754 (+) 1197 WP_003081585.1 acetate kinase -
  DYB47_RS01385 (NCTC11558_00280) - 238981..239658 (+) 678 WP_003080765.1 CPBP family intramembrane glutamic endopeptidase -
  DYB47_RS01390 (NCTC11558_00281) proC 239749..240519 (-) 771 WP_003080000.1 pyrroline-5-carboxylate reductase -
  DYB47_RS01395 (NCTC11558_00282) pepA 240599..241666 (-) 1068 WP_003081259.1 glutamyl aminopeptidase -
  DYB47_RS01400 (NCTC11558_00283) - 241766..242053 (+) 288 WP_003078939.1 DUF4651 domain-containing protein -
  DYB47_RS01405 (NCTC11558_00284) - 242057..242374 (+) 318 WP_003079465.1 thioredoxin family protein -

Sequence

Protein


Download         Length: 319 a.a.        Molecular weight: 36787.10 Da        Isoelectric Point: 4.4834

>NTDB_id=1171298 DYB47_RS01375 WP_003080448.1 236544..237503(+) (comYH) [Streptococcus macacae NCTC 11558]
MNFENIETAYNLILENCQRLEIQLQTTNLYEALIEQNVCFINSEDITDKKIKENNEKLRYLNLSEEEWRRSFQFIFIKAM
KDQFLQANHQFTPDSIAFILLYLLEELTHSPQLDILEIGSGTGNLAETLVINSQKTLDYMGIEVDDLLIDLAASIADVIG
TDISFVQEDAIRPQILKESDVIISDLPIGYYPNDNIAKRYQVASLSEHTYAHHLLMEQSLKYLKKDGIALFLAPNNLLTS
PQSDLLKKWLKDYANLIAVITLPENLFENKAYAKTIFILKKHIDNIPETFVYPLSDLQAHENITAFMESFKKWKLDNSI

Nucleotide


Download         Length: 960 bp        

>NTDB_id=1171298 DYB47_RS01375 WP_003080448.1 236544..237503(+) (comYH) [Streptococcus macacae NCTC 11558]
ATGAACTTTGAAAATATAGAAACTGCCTATAACTTGATTTTAGAGAATTGCCAGCGCTTAGAGATACAATTACAAACAAC
AAATCTTTATGAAGCTTTGATTGAACAAAATGTTTGTTTTATAAATTCTGAAGATATCACAGATAAGAAAATTAAAGAAA
ATAATGAAAAATTGCGCTATCTTAATCTTAGTGAAGAAGAGTGGCGAAGAAGTTTTCAATTTATTTTTATTAAGGCTATG
AAAGACCAGTTTTTACAGGCTAATCACCAATTTACACCGGATAGTATAGCTTTCATTCTTCTTTATTTATTAGAAGAATT
AACTCACTCGCCTCAATTGGACATTCTTGAAATTGGCTCGGGTACCGGAAATTTAGCAGAAACTTTGGTTATTAATAGTC
AGAAAACGCTGGATTATATGGGGATTGAAGTTGATGATCTCTTAATTGATCTAGCGGCGAGTATTGCAGATGTCATAGGG
ACAGATATTTCTTTTGTTCAGGAAGATGCCATTCGCCCACAGATTTTAAAAGAAAGCGATGTTATCATTAGTGATCTGCC
TATCGGTTATTATCCTAACGATAATATTGCAAAGCGATATCAAGTAGCTAGCCTAAGCGAGCATACTTATGCTCATCATC
TTTTAATGGAACAATCGCTTAAGTATCTCAAAAAAGATGGAATTGCTTTATTTTTAGCACCAAATAATTTATTAACCAGT
CCTCAAAGCGATCTTTTAAAAAAATGGTTAAAGGATTACGCCAACCTCATCGCAGTTATTACTTTGCCGGAAAATTTATT
TGAAAATAAGGCTTATGCAAAAACGATTTTTATTTTAAAGAAACATATAGATAATATACCAGAGACTTTTGTTTATCCTC
TATCAGATTTGCAAGCTCATGAAAATATAACAGCCTTTATGGAAAGCTTCAAAAAGTGGAAATTGGATAATTCCATTTAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(90-291)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G5JWB4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA159

69.085

99.373

0.687
  comYH Streptococcus mutans UA140

69.085

99.373

0.687

Multiple sequence alignment