Detailed information NTG1170471

Bioinformatically predicted

Overview

• Name: comGC/cglC
• Type: Machinery gene
• Locus tag: ACLV7W_RS09935
• Genome accession: NZ_OZ217346
• Coordinates: 2053281..2053604 (-)
• Length: 107 a.a.
• NCBI ID: WP_000738641.1
• Uniprot ID: -
• Organism: Streptococcus mitis isolate S. mitis D22
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2048281..2058604

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLV7W_RS09895 (SMID22_20350)	rnpA	2048409..2048780 (-)	372	WP_411865876.1	ribonuclease P protein component	-
ACLV7W_RS09900 (SMID22_20360)	-	2048930..2050120 (-)	1191	WP_060627210.1	acetate kinase	-
ACLV7W_RS09905 (SMID22_20370)	comYH	2050170..2051123 (-)	954	WP_411865877.1	class I SAM-dependent methyltransferase	Machinery gene
ACLV7W_RS09910 (SMID22_20380)	-	2051184..2051771 (-)	588	WP_411865878.1	class I SAM-dependent methyltransferase	-
ACLV7W_RS09915 (SMID22_20390)	comGG/cglG	2051804..2052217 (-)	414	WP_322741434.1	competence type IV pilus minor pilin ComGG	Machinery gene
ACLV7W_RS09920 (SMID22_20400)	comGF/cglF	2052195..2052656 (-)	462	WP_411865879.1	competence type IV pilus minor pilin ComGF	Machinery gene
ACLV7W_RS09925 (SMID22_20410)	comGE/cglE	2052619..2052921 (-)	303	WP_411865880.1	competence type IV pilus minor pilin ComGE	Machinery gene
ACLV7W_RS09930 (SMID22_20420)	comGD/cglD	2052884..2053318 (-)	435	WP_411865881.1	competence type IV pilus minor pilin ComGD	Machinery gene
ACLV7W_RS09935 (SMID22_20430)	comGC/cglC	2053281..2053604 (-)	324	WP_000738641.1	comG operon protein ComGC	Machinery gene
ACLV7W_RS09940 (SMID22_20440)	comGB/cglB	2053606..2054622 (-)	1017	WP_411865944.1	competence type IV pilus assembly protein ComGB	Machinery gene
ACLV7W_RS09945 (SMID22_20450)	comGA/cglA/cilD	2054570..2055511 (-)	942	WP_411865882.1	competence type IV pilus ATPase ComGA	Machinery gene
ACLV7W_RS09950 (SMID22_20460)	-	2055590..2055955 (-)	366	WP_000286409.1	DUF1033 family protein	-
ACLV7W_RS09955	-	2055982..2056206 (-)	225	WP_411865883.1	hypothetical protein	-
ACLV7W_RS09960 (SMID22_20480)	-	2056167..2057693 (+)	1527	WP_411865884.1	IS1182 family transposase	-

Sequence

Protein

• Length: 107 a.a.
• Molecular weight: 11958.09 Da
• Isoelectric Point: 9.9097

>NTDB_id=1170471 ACLV7W_RS09935 WP_000738641.1 2053281..2053604(-) (comGC/cglC) [Streptococcus mitis isolate S. mitis D22]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLLLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLDKNEDASLSKLQA
DGRITEEQAKAYKEYHAKQNTSQTVAD

Nucleotide

• Length: 324 bp

>NTDB_id=1170471 ACLV7W_RS09935 WP_000738641.1 2053281..2053604(-) (comGC/cglC) [Streptococcus mitis isolate S. mitis D22]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACTCTGGTAGAGATGTTGGTGGTCTTGCTCAT
CATCAGCGTGCTTCTCTTGCTCTTTGTACCTAATTTGACCAAGCAAAAAGAGGCGGTCAATGACAAAGGAAAAGCTGCTG
TTGTTAAGGTGGTGGAAAGTCAGGCAGAGCTTTATAGCTTGGATAAAAATGAAGATGCTAGCCTAAGTAAGTTACAAGCA
GATGGGCGAATCACAGAAGAACAGGCTAAAGCTTATAAAGAATACCATGCTAAACAAAATACCAGTCAAACCGTTGCAGA
TTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (11-34)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC/cglC	Streptococcus mitis NCTC 12261	100	100	1
comGC/cglC	Streptococcus mitis SK321	93.204	96.262	0.897
comGC/cglC	Streptococcus pneumoniae Rx1	92.157	95.327	0.879
comGC/cglC	Streptococcus pneumoniae D39	92.157	95.327	0.879
comGC/cglC	Streptococcus pneumoniae R6	92.157	95.327	0.879
comGC/cglC	Streptococcus pneumoniae TIGR4	90.291	96.262	0.869
comYC	Streptococcus gordonii str. Challis substr. CH1	69.524	98.131	0.682
comYC	Streptococcus mutans UA140	68.421	88.785	0.607
comYC	Streptococcus mutans UA159	68.421	88.785	0.607
comYC	Streptococcus suis isolate S10	70.37	75.701	0.533
comGC	Lactococcus lactis subsp. cremoris KW2	54.455	94.393	0.514
comGC	Staphylococcus aureus MW2	51.163	80.374	0.411
comGC	Staphylococcus aureus N315	51.163	80.374	0.411