Detailed information NTG1170467

Bioinformatically predicted

Overview

• Name: comGG/cglG
• Type: Machinery gene
• Locus tag: ACLV7W_RS09915
• Genome accession: NZ_OZ217346
• Coordinates: 2051804..2052217 (-)
• Length: 137 a.a.
• NCBI ID: WP_322741434.1
• Uniprot ID: A0A6I1UHE5
• Organism: Streptococcus mitis isolate S. mitis D22
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2046804..2057217

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACLV7W_RS09890 (SMID22_20340)	-	2047610..2048434 (-)	825	WP_411865875.1	membrane protein insertase YidC	-
ACLV7W_RS09895 (SMID22_20350)	rnpA	2048409..2048780 (-)	372	WP_411865876.1	ribonuclease P protein component	-
ACLV7W_RS09900 (SMID22_20360)	-	2048930..2050120 (-)	1191	WP_060627210.1	acetate kinase	-
ACLV7W_RS09905 (SMID22_20370)	comYH	2050170..2051123 (-)	954	WP_411865877.1	class I SAM-dependent methyltransferase	Machinery gene
ACLV7W_RS09910 (SMID22_20380)	-	2051184..2051771 (-)	588	WP_411865878.1	class I SAM-dependent methyltransferase	-
ACLV7W_RS09915 (SMID22_20390)	comGG/cglG	2051804..2052217 (-)	414	WP_322741434.1	competence type IV pilus minor pilin ComGG	Machinery gene
ACLV7W_RS09920 (SMID22_20400)	comGF/cglF	2052195..2052656 (-)	462	WP_411865879.1	competence type IV pilus minor pilin ComGF	Machinery gene
ACLV7W_RS09925 (SMID22_20410)	comGE/cglE	2052619..2052921 (-)	303	WP_411865880.1	competence type IV pilus minor pilin ComGE	Machinery gene
ACLV7W_RS09930 (SMID22_20420)	comGD/cglD	2052884..2053318 (-)	435	WP_411865881.1	competence type IV pilus minor pilin ComGD	Machinery gene
ACLV7W_RS09935 (SMID22_20430)	comGC/cglC	2053281..2053604 (-)	324	WP_000738641.1	comG operon protein ComGC	Machinery gene
ACLV7W_RS09940 (SMID22_20440)	comGB/cglB	2053606..2054622 (-)	1017	WP_411865944.1	competence type IV pilus assembly protein ComGB	Machinery gene
ACLV7W_RS09945 (SMID22_20450)	comGA/cglA/cilD	2054570..2055511 (-)	942	WP_411865882.1	competence type IV pilus ATPase ComGA	Machinery gene
ACLV7W_RS09950 (SMID22_20460)	-	2055590..2055955 (-)	366	WP_000286409.1	DUF1033 family protein	-
ACLV7W_RS09955	-	2055982..2056206 (-)	225	WP_411865883.1	hypothetical protein	-

Sequence

Protein

• Length: 137 a.a.
• Molecular weight: 15789.19 Da
• Isoelectric Point: 10.3213

>NTDB_id=1170467 ACLV7W_RS09915 WP_322741434.1 2051804..2052217(-) (comGG/cglG) [Streptococcus mitis isolate S. mitis D22]
MWKKKKVKAGVLLYAVTISAIFSLLLQFYLNRQVAHYQDYAVNKEKLIAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKK
TGLVTTVRTPKSQYEFLFPSVKIKEEKTDKKEKVVTDSSNQAEKKKSEEKSEKKENS

Nucleotide

• Length: 414 bp

>NTDB_id=1170467 ACLV7W_RS09915 WP_322741434.1 2051804..2052217(-) (comGG/cglG) [Streptococcus mitis isolate S. mitis D22]
GTGTGGAAAAAGAAAAAAGTTAAGGCAGGAGTTCTCCTCTATGCAGTCACCATTTCAGCCATTTTCAGCCTTTTATTGCA
GTTCTATTTGAACCGACAAGTCGCCCACTATCAAGACTATGCTGTAAATAAAGAAAAGTTAATCGCTTTTGCCATGGCTA
AACGAACCAAGGATAAAGCCGAGCAAGAAAGTGGGGAGCAGGTCTTTAATCTAGGTCAGGTAAGCTATCAAAACAAGAAA
ACTGGCTTGGTGACGACGGTTCGTACGCCTAAGAGTCAATATGAGTTCCTATTTCCTTCAGTCAAAATCAAAGAAGAGAA
AACGGATAAAAAGGAAAAGGTAGTGACTGATTCAAGTAATCAAGCGGAAAAGAAAAAATCAGAAGAGAAGTCTGAAAAGA
AAGAGAATTCCTAG

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A6I1UHE5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGG/cglG	Streptococcus mitis SK321	90.511	100	0.905
comGG/cglG	Streptococcus mitis NCTC 12261	91.803	89.051	0.818
comGG/cglG	Streptococcus pneumoniae D39	91.453	85.401	0.781
comGG/cglG	Streptococcus pneumoniae TIGR4	91.453	85.401	0.781
comGG/cglG	Streptococcus pneumoniae R6	91.453	85.401	0.781
comGG/cglG	Streptococcus pneumoniae Rx1	91.453	85.401	0.781
comYG	Streptococcus mutans UA140	37.778	98.54	0.372
comYG	Streptococcus mutans UA159	37.778	98.54	0.372